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A comprehensive simulation-based met...

Arnone, Joshua.

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A comprehensive simulation-based methodology for the design and optimization of orthopaedic internal fixation implants.

Record Type:	Electronic resources : Monograph/item
Title/Author:	A comprehensive simulation-based methodology for the design and optimization of orthopaedic internal fixation implants./
Author:	Arnone, Joshua.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2011,
Description:	221 p.
Notes:	Source: Dissertations Abstracts International, Volume: 74-07, Section: B.
Contained By:	Dissertations Abstracts International74-07B.
Subject:	Mechanical engineering. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3533860
ISBN:	9781267793591

A comprehensive simulation-based methodology for the design and optimization of orthopaedic internal fixation implants.
Arnone, Joshua.

A comprehensive simulation-based methodology for the design and optimization of orthopaedic internal fixation implants. - Ann Arbor : ProQuest Dissertations & Theses, 2011 - 221 p.

Source: Dissertations Abstracts International, Volume: 74-07, Section: B.

Thesis (Ph.D.)--University of Missouri - Columbia, 2011.

This item must not be added to any third party search indexes.

Internal fixation implants are widely used by orthopaedic surgeons to stabilize various types of fractures in injured patients. However, the irregular geometry of the human skeletal system, as well as the significant variation in the size and shape of bones among the population, pose great challenges in efficiently and effectively designing such devices. As a result, the need for improvement in regard to performance and fit is evident in many current internal fixation implants, particularly for high load-bearing regions such as the femur. For this reason, a comprehensive methodology was developed to design and optimize implants with maximal structural integrity and contour fitting among the population, while minimizing its influence on human biomechanics. The systematic methodology uniquely employs both new and existing techniques in medical imaging analysis, non-linear finite element methods, and optimization to obtain optimal designs prior to experimental testing. Its efficacy was demonstrated using two case studies involving the design of internal fixation implants used to stabilize various femoral shaft fractures: intramedullary nailing and locking plate systems. Comparison of finite element results - from simulated physiological loading conditions and loads induced by "virtual surgery" - among the optimized implants and those currently used in the operating room showed much improvement in regard to reliability, fit, and alteration of natural biomechanics. Subsequent experimental testing verified that the results predicted by the developed simulation-based methodology represented actual physiological scenarios within acceptable percent error and were valid for design purposes.

ISBN: 9781267793591Subjects--Topical Terms:

649730
Mechanical engineering.
Subjects--Index Terms:

Contour fitting

A comprehensive simulation-based methodology for the design and optimization of orthopaedic internal fixation implants.
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245 1 2 $a A comprehensive simulation-based methodology for the design and optimization of orthopaedic internal fixation implants.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2011
300 $a 221 p.
500 $a Source: Dissertations Abstracts International, Volume: 74-07, Section: B.
500 $a Publisher info.: Dissertation/Thesis.
500 $a Advisor: El-Gizawy, A. Sherif.
502 $a Thesis (Ph.D.)--University of Missouri - Columbia, 2011.
506 $a This item must not be added to any third party search indexes.
506 $a This item must not be sold to any third party vendors.
506 $a This item is not available from ProQuest Dissertations & Theses.
520 $a Internal fixation implants are widely used by orthopaedic surgeons to stabilize various types of fractures in injured patients. However, the irregular geometry of the human skeletal system, as well as the significant variation in the size and shape of bones among the population, pose great challenges in efficiently and effectively designing such devices. As a result, the need for improvement in regard to performance and fit is evident in many current internal fixation implants, particularly for high load-bearing regions such as the femur. For this reason, a comprehensive methodology was developed to design and optimize implants with maximal structural integrity and contour fitting among the population, while minimizing its influence on human biomechanics. The systematic methodology uniquely employs both new and existing techniques in medical imaging analysis, non-linear finite element methods, and optimization to obtain optimal designs prior to experimental testing. Its efficacy was demonstrated using two case studies involving the design of internal fixation implants used to stabilize various femoral shaft fractures: intramedullary nailing and locking plate systems. Comparison of finite element results - from simulated physiological loading conditions and loads induced by "virtual surgery" - among the optimized implants and those currently used in the operating room showed much improvement in regard to reliability, fit, and alteration of natural biomechanics. Subsequent experimental testing verified that the results predicted by the developed simulation-based methodology represented actual physiological scenarios within acceptable percent error and were valid for design purposes.
590 $a School code: 0133.
650 4 $a Mechanical engineering. $3 649730
650 4 $a Biomechanics. $3 548685
653 $a Contour fitting
653 $a Femoral shaft fractures
653 $a Internal fixation implants
653 $a Maximal structural integrity
653 $a Orthopaedic surgeons
690 $a 0548
690 $a 0648
710 2 $a University of Missouri - Columbia. $3 1017522
773 0 $t Dissertations Abstracts International $g 74-07B.
790 $a 0133
791 $a Ph.D.
792 $a 2011
793 $a English
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3533860