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High-Throughput Refractive Index Qua...

DeLuna, Frank.

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High-Throughput Refractive Index Quantification via Photonic-Crystal Biosensor Microscopy.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	High-Throughput Refractive Index Quantification via Photonic-Crystal Biosensor Microscopy./
作者:	DeLuna, Frank.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2023,
面頁冊數:	106 p.
附註:	Source: Dissertations Abstracts International, Volume: 84-11, Section: B.
Contained By:	Dissertations Abstracts International84-11B.
標題:	Biomedical engineering. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30489134
ISBN:	9798379578145

High-Throughput Refractive Index Quantification via Photonic-Crystal Biosensor Microscopy.
DeLuna, Frank.

High-Throughput Refractive Index Quantification via Photonic-Crystal Biosensor Microscopy. - Ann Arbor : ProQuest Dissertations & Theses, 2023 - 106 p.

Source: Dissertations Abstracts International, Volume: 84-11, Section: B.

Thesis (Ph.D.)--The University of Texas at San Antonio, 2023.

This item must not be sold to any third party vendors.

The work presented in this dissertation describes the development and application of a Photonic-Crystal based biosensor in a Total-Internal-Reflection (PC-TIR) configuration for various biomedical applications. The biosensor utilizes refractive index (RI) as a means of detecting and distinguishing between different cell types and biomolecules. Specifically, we demonstrate the use of the PC-TIR biosensor for the detection of prostate cancer cells and the evaluation of prostate cancer progression using cellular RI as the only contrast parameter. Additionally, we report the development of a high-throughput, multiplexed, antibody-antigen biosensor based on the PC-TIR biosensor for accurate analysis of biomarkers pertinent to traumatic brain injury (TBI). This study highlights the potential of the PC-TIR biosensor as a powerful and versatile platform for various biosensing applications.

ISBN: 9798379578145Subjects--Topical Terms:

535387
Biomedical engineering.
Subjects--Index Terms:

Photonic-Crystal biosensor

High-Throughput Refractive Index Quantification via Photonic-Crystal Biosensor Microscopy.
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300 $a 106 p.
500 $a Source: Dissertations Abstracts International, Volume: 84-11, Section: B.
500 $a Advisor: Yong Ye, Jing.
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506 $a This item must not be sold to any third party vendors.
520 $a The work presented in this dissertation describes the development and application of a Photonic-Crystal based biosensor in a Total-Internal-Reflection (PC-TIR) configuration for various biomedical applications. The biosensor utilizes refractive index (RI) as a means of detecting and distinguishing between different cell types and biomolecules. Specifically, we demonstrate the use of the PC-TIR biosensor for the detection of prostate cancer cells and the evaluation of prostate cancer progression using cellular RI as the only contrast parameter. Additionally, we report the development of a high-throughput, multiplexed, antibody-antigen biosensor based on the PC-TIR biosensor for accurate analysis of biomarkers pertinent to traumatic brain injury (TBI). This study highlights the potential of the PC-TIR biosensor as a powerful and versatile platform for various biosensing applications.
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653 $a Biomedical applications
653 $a Traumatic brain injury
653 $a Cancer cells
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