東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Is Risk Compensation Real? The Effec...

Rankin, Kelsey A.

Linked to FindBook

Google Book

Amazon

博客來

Is Risk Compensation Real? The Effect of Perceived Level of HIV Acquisition on Risk Behavior in a Pilot Pre-exposure Prophylaxis Demonstration Project in Men Who Have Sex With Men in Malaysia.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Is Risk Compensation Real? The Effect of Perceived Level of HIV Acquisition on Risk Behavior in a Pilot Pre-exposure Prophylaxis Demonstration Project in Men Who Have Sex With Men in Malaysia./
Author:	Rankin, Kelsey A.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2023,
Description:	49 p.
Notes:	Source: Dissertations Abstracts International, Volume: 85-01, Section: B.
Contained By:	Dissertations Abstracts International85-01B.
Subject:	Medicine. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30311534
ISBN:	9798379795009

Is Risk Compensation Real? The Effect of Perceived Level of HIV Acquisition on Risk Behavior in a Pilot Pre-exposure Prophylaxis Demonstration Project in Men Who Have Sex With Men in Malaysia.
Rankin, Kelsey A.

Is Risk Compensation Real? The Effect of Perceived Level of HIV Acquisition on Risk Behavior in a Pilot Pre-exposure Prophylaxis Demonstration Project in Men Who Have Sex With Men in Malaysia. - Ann Arbor : ProQuest Dissertations & Theses, 2023 - 49 p.

Source: Dissertations Abstracts International, Volume: 85-01, Section: B.

Thesis (M.D.)--Yale University, 2023.

This item must not be sold to any third party vendors.

Pre-exposure prophylaxis (PrEP) is highly effective in human immunodeficiency virus (HIV) prevention for key populations, including men who have sex with men (MSM). In Malaysia, human immunodeficiency virus (HIV) prevalence among MSM is 22%, and is even higher in key urban areas, including Kuala Lumpur. Despite nationwide campaigns committed to address HIV, scale-up of PrEP for MSM in Malaysia has been suboptimal. This limitation can be attributed partially to concerns that PrEP will lead to increased sexual risk behaviors, based on the controversial theory of risk compensation.{A0}A 2018 PrEP demonstration study of MSM in Malaysia (n=150) was used to assess changes in sexual risk behaviors after PrEP initiation, exploring risk compensation. Changes in sexual risk behaviors between baseline and follow-up (months 3, 6, 9, and 12) were tested using Wilcoxon signed-rank and McNemer's tests for non-parametric continuous and paired binary variables, respectively. Generalized estimating equations were used to model risk outcome behaviors. Significance was set at p<0.05 for all analyses.{A0}{A0}Participants were mostly single (62.0%), gay (92.0%), young (mean age: 31.33 + 7.36), and employed full-time (81.3%). Participants reported a small but statistically significant increase in sexual partners compared to baseline at all timepoints (all p<0.001), peaking at month 6, and then decreasing significantly thereafter (9 months: p=0.002; 12 months: p=0.001). There was no change in the risk behaviors{A0}of condomless anal sex (CAS) or CAS with an HIV+ partner at any timepoint. Baseline HIV risk perception could not predict any change in any risk behavior. Increased number of missed pills was significantly associated with decreased CAS (p=0.003).Lack of associations between baseline HIV risk perception and changes in any sexual risk behavior, as well as lack of changes in CAS and CAS with an HIV+ partner, undermines the notion of risk compensation in MSM while using PrEP. We advocate for the Malaysian government's endorsement, subsidization, and increased utilization of PrEP in the MSM community.

ISBN: 9798379795009Subjects--Topical Terms:

641104
Medicine.
Subjects--Index Terms:

HIV

Is Risk Compensation Real? The Effect of Perceived Level of HIV Acquisition on Risk Behavior in a Pilot Pre-exposure Prophylaxis Demonstration Project in Men Who Have Sex With Men in Malaysia.
LDR:03455nmm a2200409 4500 001 2393133
005 20240311061547.5
006 m o d
007 cr#unu||||||||
008 251215s2023 ||||||||||||||||| ||eng d
020 $a 9798379795009
035 $a (MiAaPQ)AAI30311534
035 $a AAI30311534
040 $a MiAaPQ $c MiAaPQ
100 1 $a Rankin, Kelsey A. $3 3762574
245 1 0 $a Is Risk Compensation Real? The Effect of Perceived Level of HIV Acquisition on Risk Behavior in a Pilot Pre-exposure Prophylaxis Demonstration Project in Men Who Have Sex With Men in Malaysia.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2023
300 $a 49 p.
500 $a Source: Dissertations Abstracts International, Volume: 85-01, Section: B.
500 $a Advisor: Herzog, Erica.
502 $a Thesis (M.D.)--Yale University, 2023.
506 $a This item must not be sold to any third party vendors.
520 $a Pre-exposure prophylaxis (PrEP) is highly effective in human immunodeficiency virus (HIV) prevention for key populations, including men who have sex with men (MSM). In Malaysia, human immunodeficiency virus (HIV) prevalence among MSM is 22%, and is even higher in key urban areas, including Kuala Lumpur. Despite nationwide campaigns committed to address HIV, scale-up of PrEP for MSM in Malaysia has been suboptimal. This limitation can be attributed partially to concerns that PrEP will lead to increased sexual risk behaviors, based on the controversial theory of risk compensation.{A0}A 2018 PrEP demonstration study of MSM in Malaysia (n=150) was used to assess changes in sexual risk behaviors after PrEP initiation, exploring risk compensation. Changes in sexual risk behaviors between baseline and follow-up (months 3, 6, 9, and 12) were tested using Wilcoxon signed-rank and McNemer's tests for non-parametric continuous and paired binary variables, respectively. Generalized estimating equations were used to model risk outcome behaviors. Significance was set at p<0.05 for all analyses.{A0}{A0}Participants were mostly single (62.0%), gay (92.0%), young (mean age: 31.33 + 7.36), and employed full-time (81.3%). Participants reported a small but statistically significant increase in sexual partners compared to baseline at all timepoints (all p<0.001), peaking at month 6, and then decreasing significantly thereafter (9 months: p=0.002; 12 months: p=0.001). There was no change in the risk behaviors{A0}of condomless anal sex (CAS) or CAS with an HIV+ partner at any timepoint. Baseline HIV risk perception could not predict any change in any risk behavior. Increased number of missed pills was significantly associated with decreased CAS (p=0.003).Lack of associations between baseline HIV risk perception and changes in any sexual risk behavior, as well as lack of changes in CAS and CAS with an HIV+ partner, undermines the notion of risk compensation in MSM while using PrEP. We advocate for the Malaysian government's endorsement, subsidization, and increased utilization of PrEP in the MSM community.
590 $a School code: 0265.
650 4 $a Medicine. $3 641104
650 4 $a Public health. $3 534748
650 4 $a Pathology. $3 643180
650 4 $a Biostatistics. $3 1002712
653 $a HIV
653 $a Pre-exposure prophylaxis
653 $a MSM community
653 $a Sexual risk behaviors
653 $a Malaysia
690 $a 0564
690 $a 0308
690 $a 0573
690 $a 0571
710 2 $a Yale University. $b Yale School of Medicine. $3 3422308
773 0 $t Dissertations Abstracts International $g 85-01B.
790 $a 0265
791 $a M.D.
792 $a 2023
793 $a English
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30311534