東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

The major histocompatibility complex...

Garrido, Federico.

FindBook

Google Book

Amazon

博客來

The major histocompatibility complex (MHC/ HLA) in medicine = a personal recollection /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The major histocompatibility complex (MHC/ HLA) in medicine/ by Federico Garrido.
其他題名:	a personal recollection /
作者:	Garrido, Federico.
出版者:	Cham :Springer International Publishing : : 2024.,
面頁冊數:	xi, 108 p. :ill. (chiefly col.), digital ;24 cm.
內容註:	Chapter 1: The discovery of the Major Histocompatibility Complex (MHC): The H-2 in mice and the HLA in humans -- Chapter 2: The discovery of the biological function of the MHC -- Chapter 3: HLA genes and molecules -- Chapter 4: HLA in transplantation -- Chapter 5: HLA class-I loss and cancer Immune escape -- Chapter 6: HLA and disease association -- Chapter 7: HLA in population genetics.
Contained By:	Springer Nature eBook
標題:	Major histocompatibility complex. -
電子資源:	https://doi.org/10.1007/978-3-031-59866-1
ISBN:	9783031598661

The major histocompatibility complex (MHC/ HLA) in medicine = a personal recollection /
Garrido, Federico.

The major histocompatibility complex (MHC/ HLA) in medicinea personal recollection /[electronic resource] :by Federico Garrido. - Cham :Springer International Publishing :2024. - xi, 108 p. :ill. (chiefly col.), digital ;24 cm.

Chapter 1: The discovery of the Major Histocompatibility Complex (MHC): The H-2 in mice and the HLA in humans -- Chapter 2: The discovery of the biological function of the MHC -- Chapter 3: HLA genes and molecules -- Chapter 4: HLA in transplantation -- Chapter 5: HLA class-I loss and cancer Immune escape -- Chapter 6: HLA and disease association -- Chapter 7: HLA in population genetics.

This book takes the reader on a journey through past and current research on the Major Histocompatibility Complex (MHC/HLA) It describes how it was discovered, what its biological function is and its application in medicine. The reader will learn about the molecular structure of the encoded molecules and different aspects of their role in medicine, including organ transplantation, their link to autoimmune diseases, cancer immunity, resistance to infectious diseases, and other related scientific areas, such as population genetics. In particular, the book focusses on the impact of MHC/HLA altered expression in tumours and their relevance in cancer immune escape and immunotherapy. It contains a large number of original figures and photographs of pioneers in the field, who made seminal contributions. Each chapter is supported by relevant key publications and enriched with a personal account of the early research that has contributed to our current understanding of the role of the major histocompatibility complex. This book is an excellent resource for all scientists in the biomedical life sciences who wish to gain insight into the discovery of the MHC/HLA and the role of this important genetic complex in health and disease.

ISBN: 9783031598661

Standard No.: 10.1007/978-3-031-59866-1doiSubjects--Topical Terms:

3722077
Major histocompatibility complex.

LC Class. No.: QR184.315

Dewey Class. No.: 616.079

The major histocompatibility complex (MHC/ HLA) in medicine = a personal recollection /
LDR:02658nmm a2200325 a 4500 001 2373721
003 DE-He213
005 20240712125357.0
006 m d
007 cr nn 008maaau
008 241231s2024 sz s 0 eng d
020 $a 9783031598661 $q (electronic bk.)
020 $a 9783031598654 $q (paper)
024 7 $a 10.1007/978-3-031-59866-1 $2 doi
035 $a 978-3-031-59866-1
040 $a GP $c GP
041 0 $a eng
050 4 $a QR184.315
072 7 $a MJCM $2 bicssc
072 7 $a MED044000 $2 bisacsh
072 7 $a MJCM $2 thema
082 0 4 $a 616.079 $2 23
090 $a QR184.315 $b .G241 2024
100 1 $a Garrido, Federico. $3 3410168
245 1 4 $a The major histocompatibility complex (MHC/ HLA) in medicine $h [electronic resource] : $b a personal recollection / $c by Federico Garrido.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2024.
300 $a xi, 108 p. : $b ill. (chiefly col.), digital ; $c 24 cm.
505 0 $a Chapter 1: The discovery of the Major Histocompatibility Complex (MHC): The H-2 in mice and the HLA in humans -- Chapter 2: The discovery of the biological function of the MHC -- Chapter 3: HLA genes and molecules -- Chapter 4: HLA in transplantation -- Chapter 5: HLA class-I loss and cancer Immune escape -- Chapter 6: HLA and disease association -- Chapter 7: HLA in population genetics.
520 $a This book takes the reader on a journey through past and current research on the Major Histocompatibility Complex (MHC/HLA) It describes how it was discovered, what its biological function is and its application in medicine. The reader will learn about the molecular structure of the encoded molecules and different aspects of their role in medicine, including organ transplantation, their link to autoimmune diseases, cancer immunity, resistance to infectious diseases, and other related scientific areas, such as population genetics. In particular, the book focusses on the impact of MHC/HLA altered expression in tumours and their relevance in cancer immune escape and immunotherapy. It contains a large number of original figures and photographs of pioneers in the field, who made seminal contributions. Each chapter is supported by relevant key publications and enriched with a personal account of the early research that has contributed to our current understanding of the role of the major histocompatibility complex. This book is an excellent resource for all scientists in the biomedical life sciences who wish to gain insight into the discovery of the MHC/HLA and the role of this important genetic complex in health and disease.
650 0 $a Major histocompatibility complex. $3 3722077
650 1 4 $a Immunology. $3 611031
650 2 4 $a Cancer Biology. $3 3594253
650 2 4 $a Genetics and Genomics. $3 3385208
650 2 4 $a Cancer Genetics and Genomics. $3 3591654
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-3-031-59866-1
950 $a Biomedical and Life Sciences (SpringerNature-11642)