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Magnetoacoustic Tomography with Magnetic Induction for Electrical Conductivity Imaging of Biological Tissue.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Magnetoacoustic Tomography with Magnetic Induction for Electrical Conductivity Imaging of Biological Tissue./
作者:
Li, Xu.
面頁冊數:
1 online resource (177 pages)
附註:
Source: Dissertations Abstracts International, Volume: 73-05, Section: B.
Contained By:
Dissertations Abstracts International73-05B.
標題:
Biomedical engineering. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3478108click for full text (PQDT)
ISBN:
9781124953229
Magnetoacoustic Tomography with Magnetic Induction for Electrical Conductivity Imaging of Biological Tissue.
Li, Xu.
Magnetoacoustic Tomography with Magnetic Induction for Electrical Conductivity Imaging of Biological Tissue.
- 1 online resource (177 pages)
Source: Dissertations Abstracts International, Volume: 73-05, Section: B.
Thesis (Ph.D.)--University of Minnesota, 2010.
Includes bibliographical references
Electrical properties of biological tissue including conductivity and permittivity play important roles in many biomedical and clinical researches such as modeling neural or cardiac electrical activities and management of electromagnetic energy delivery to the body during clinical diagnosis and treatment. More importantly, these electrical properties may serve as an intrinsic contrast for anatomical or functional imaging. It is therefore of great value to noninvasively image the electrical properties of biological tissue with good accuracy and high spatial resolution. This dissertation research aims at developing and evaluating a new modality i.e. magnetoacoustic tomography with magnetic induction (MAT-MI), for imaging electrical conductivity distribution of biological tissue. In MAT-MI, a conductive object is placed in a static magnetic field and a time-varying magnetic stimulation is applied to induce eddy current inside the object volume. Within the static magnetic field, the Lorentz force acting on the induced eddy current causes mechanical movement of those charged particles in the object and leads to detectable ultrasound signals. These ultrasound signals can be acquired by ultrasound probes and used to reconstruct a high spatial resolution image that indicates the object's electrical conductivity contrast. We have proposed and investigated two types of MAT-MI approaches i.e. single-excitation MAT-MI and multi-excitation MAT-MI. The corresponding image reconstruction algorithms, simulation protocols and experiment systems have been developed for feasibility testing and performance evaluation. It is shown in our computer simulation and experiment studies that using the single-excitation MAT-MI we are able to image the conductivity boundaries of the object with several millimeter spatial resolution. In addition, we have also demonstrated that the multiexcitation MAT-MI approach allows us to further extract the internal information and reconstruct more completely the conductivity contrast of the object. For both approaches, two-dimensional (2D) and three-dimensional (3D) images of physical or tissue phantoms have been acquired and showed promising agreement with the target conductivity distribution. All the results we have collected so far from simulations and experiments suggest that the MAT-MI approach is potential to become an important noninvasive modality for electrical conductivity imaging of biological tissue.
Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2023
Mode of access: World Wide Web
ISBN: 9781124953229Subjects--Topical Terms:
535387
Biomedical engineering.
Subjects--Index Terms:
BioimpedanceIndex Terms--Genre/Form:
542853
Electronic books.
Magnetoacoustic Tomography with Magnetic Induction for Electrical Conductivity Imaging of Biological Tissue.
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Electrical properties of biological tissue including conductivity and permittivity play important roles in many biomedical and clinical researches such as modeling neural or cardiac electrical activities and management of electromagnetic energy delivery to the body during clinical diagnosis and treatment. More importantly, these electrical properties may serve as an intrinsic contrast for anatomical or functional imaging. It is therefore of great value to noninvasively image the electrical properties of biological tissue with good accuracy and high spatial resolution. This dissertation research aims at developing and evaluating a new modality i.e. magnetoacoustic tomography with magnetic induction (MAT-MI), for imaging electrical conductivity distribution of biological tissue. In MAT-MI, a conductive object is placed in a static magnetic field and a time-varying magnetic stimulation is applied to induce eddy current inside the object volume. Within the static magnetic field, the Lorentz force acting on the induced eddy current causes mechanical movement of those charged particles in the object and leads to detectable ultrasound signals. These ultrasound signals can be acquired by ultrasound probes and used to reconstruct a high spatial resolution image that indicates the object's electrical conductivity contrast. We have proposed and investigated two types of MAT-MI approaches i.e. single-excitation MAT-MI and multi-excitation MAT-MI. The corresponding image reconstruction algorithms, simulation protocols and experiment systems have been developed for feasibility testing and performance evaluation. It is shown in our computer simulation and experiment studies that using the single-excitation MAT-MI we are able to image the conductivity boundaries of the object with several millimeter spatial resolution. In addition, we have also demonstrated that the multiexcitation MAT-MI approach allows us to further extract the internal information and reconstruct more completely the conductivity contrast of the object. For both approaches, two-dimensional (2D) and three-dimensional (3D) images of physical or tissue phantoms have been acquired and showed promising agreement with the target conductivity distribution. All the results we have collected so far from simulations and experiments suggest that the MAT-MI approach is potential to become an important noninvasive modality for electrical conductivity imaging of biological tissue.
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