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Fixed-Platform Ballistocardiography for Hemodynamic Monitoring in Deep Space.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Fixed-Platform Ballistocardiography for Hemodynamic Monitoring in Deep Space./
Author:	McCall, Corey Scott.
Description:	1 online resource (117 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 84-04, Section: B.
Contained By:	Dissertations Abstracts International84-04B.
Subject:	Receivers & amplifiers. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29342241click for full text (PQDT)
ISBN:	9798351494012

Fixed-Platform Ballistocardiography for Hemodynamic Monitoring in Deep Space.
McCall, Corey Scott.

Fixed-Platform Ballistocardiography for Hemodynamic Monitoring in Deep Space. - 1 online resource (117 pages)

Source: Dissertations Abstracts International, Volume: 84-04, Section: B.

Thesis (Ph.D.)--Stanford University, 2022.

Includes bibliographical references

Despite this, astronauts have generally been able to survive spaceflight by monitoring their cardiovascular system and applying countermeasures as needed. However, space agencies have recently shifted their human exploration focus from near-earth to deep space, soon exposing astronauts to longer duration missions aboard smaller proposed "deep space transport" (DST) vehicles. This is unfortunately expected to amplify deconditioning, and the reduced crew volume limits the practicality of most cardiovascular monitoring instruments that have been commonly used on larger space stations where virtually all long duration missions have taken place. Without the ability to practically monitor cardiovascular change in deep space, it is not possible to study its increased effects or efficiently prescribe critical countermeasures.This work proposes the use of a novel monitoring system designed for DSTs that combines fixed-platform ballistocardiography with other noninvasive sensors to practically measure hemodynamic changes indicative of cardiovascular deconditioning.The core of the proposed system was a single-dimensional force sensing platform designed to capture the ballistocardiogram (BCG), a measurement of the recoil force of the body in reaction to cardiac ejection. The BCG signal was fused together with signals from a wearable electrocardiogram (ECG) and photoplethysmogram (PPG) to estimate several cardiovascular parameters that can be used to monitor cardiovascular deconditioning. During spaceflight, an astronaut can measure himself or herself with the system by simply maneuvering to the platform mounted to the spacecraft frame, inserting their feet into a coupling, and waiting still for a small number of heartbeats. The system overcame several engineering challenges in order to accomplish robust v signal capture while being operated by a single user in a confined microgravity environment. It also represents the first ever successful use of fixed-platform BCG in microgravity.To validate the system's quality and practicality, it was first built and characterized, then deployed for human testing in the confined microgravity environment of parabolic flight. In this experiment, the measured BCG signal was compared to the current state-of-the-art alternative, an accelerometry-based BCG designed for free-floating measurement. The proposed system was able to successfully measure standard I and J wave timings of the BCG in all subjects, as well as K wave timings in some of the subjects, while being much less cumbersome than the accelerometrybased BCG system that requires careful manual control of the floating subject. Pulse arrival at the toe and ventricular depolarization timings were also successfully measured in all subjects from the respective PPG and ECG signals. The signal-to-noise ratio of both BCGs were compared, and the BCG measured using the proposed system was higher than the accelerometry-based BCG, suggesting that it is a more robust way to measure BCG in microgravity in terms of signal quality.After validating the system's quality and practicality, the parabolic flight experiment was expanded to add normal gravity measurements of the same subjects in order to validate that hemodynamic changes could be detected. Comparing the microgravity measurement to normal gravity, significant decrease in RJ interval, increase in pulse transit time, and other changes in hemodynamic parameters were observed. These results were congruent with the expected physiological response, suggesting that the proposed system was able to detect hemodynamic changes induced by microgravity.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2023

Mode of access: World Wide Web

ISBN: 9798351494012Subjects--Topical Terms:

3559205
Receivers & amplifiers.
Index Terms--Genre/Form:

542853
Electronic books.

Fixed-Platform Ballistocardiography for Hemodynamic Monitoring in Deep Space.
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