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Effect of Local Heat Application on Mitochondrial related Gene Expression in Skeletal Muscle.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Effect of Local Heat Application on Mitochondrial related Gene Expression in Skeletal Muscle./
作者:	Kwon, Monica.
面頁冊數:	1 online resource (41 pages)
附註:	Source: Masters Abstracts International, Volume: 83-12.
Contained By:	Masters Abstracts International83-12.
標題:	Physiology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29165749click for full text (PQDT)
ISBN:	9798819399675

Effect of Local Heat Application on Mitochondrial related Gene Expression in Skeletal Muscle.
Kwon, Monica.

Effect of Local Heat Application on Mitochondrial related Gene Expression in Skeletal Muscle. - 1 online resource (41 pages)

Source: Masters Abstracts International, Volume: 83-12.

Thesis (M.S.)--University of Nebraska at Omaha, 2022.

Includes bibliographical references

PURPOSE: To determine the impact of local heat at rest on skeletal muscle gene expression related to mitochondrial biogenesis and mitophagy. METHODS: Twelve healthy subjects (height, 176.0 ± 11.9 cm; weight, 83.6 ± 18.3 kg; and body composition, 19.0 ± 7.7% body fat) rested in a semi-reclined position with a heated thermal wrap (HOT) around one thigh and wrap without temperature regulation (CON) around the other (randomized) for 4-hours. Skin temperature, femoral artery blood flow, intramuscular temperature, and a skeletal muscle biopsy from the vastus lateralis were obtained after the 4-hour intervention. RESULTS: Skin temperature via laser temperature was higher after HOT (37.3±0.7°C) than CON (34.8±0.7°C, p<0.001). Skin temperature via thermal camera was also higher after HOT (36.7±1.0°C) than CON (34.6±0.9°C, p<0.001). Intramuscular temperature was higher in HOT (36.3±0.4ºC) than CON (35.2±0.8ºC, p<0.001). There was a difference in femoral artery blood flow between HOT (304.5 ± 35.3 mL/min) and CON (272.3 ± 40.3 mL/min, p=0.003). There were no differences in any of the investigated genes related to mitochondrial biogenesis (PGC-1α, NRF1, GAPBA, ERRα, TFAM, VEGF) or mitophagy (PINK-1, PARK-2, BNIP-3, BNIP-3L) in response to heat (p>0.05). CONCLUSION: These data indicate that heat application alone has no impact on genes related to mitochondrial homeostasis, suggesting that other factors in combination with skeletal muscle temperature are involved with previous observations of altered exercise induced gene expression with heat.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2023

Mode of access: World Wide Web

ISBN: 9798819399675Subjects--Topical Terms:

518431
Physiology.
Subjects--Index Terms:

BiogenesisIndex Terms--Genre/Form:

542853
Electronic books.

Effect of Local Heat Application on Mitochondrial related Gene Expression in Skeletal Muscle.
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