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Stress, Inflammation, and Mood: A Role for Leptin?

Record Type:	Electronic resources : Monograph/item
Title/Author:	Stress, Inflammation, and Mood: A Role for Leptin?/
Author:	Hodgin, Kathleen.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2021,
Description:	85 p.
Notes:	Source: Masters Abstracts International, Volume: 83-01.
Contained By:	Masters Abstracts International83-01.
Subject:	Psychology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28491226
ISBN:	9798516074936

Stress, Inflammation, and Mood: A Role for Leptin?
Hodgin, Kathleen.

Stress, Inflammation, and Mood: A Role for Leptin? - Ann Arbor : ProQuest Dissertations & Theses, 2021 - 85 p.

Source: Masters Abstracts International, Volume: 83-01.

Thesis (M.A.)--The University of Alabama at Birmingham, 2021.

This item must not be sold to any third party vendors.

Prior research has suggested a possible role for the proinflammatory adipokine leptin in depression. Leptin has also been associated with stress, a known predictor of depression. The purpose of this project was to investigate associations between stress, leptin, and depressed mood. We used data from a larger observational study that collected daily levels of plasma leptin and self-reported stress and depressed mood from 55 women over 25 days. Women with and without chronic fatigue syndrome (CFS) were included. We hypothesized the following: increased stress would be associated with both worsened mood and higher leptin, and that leptin would be positively associated with depressed mood. Vitamin D was also explored as a potential moderating factor. Linear mixed models were used to analyze associations between daily stress, leptin, and mood at a 1-day time lag. Results suggested an association between stress and next-day leptin, dependent on vitamin D level (p = .018). Leptin also varied by patient group depending on vitamin D (p = .018), with highest leptin observed among women with CFS and lower vitamin D (< 20 ng/mL). Overall, findings support further investigation of vitamin D in relation to stress and leptin; leptin, however, does not appear to play a substantial role in depressed mood.

ISBN: 9798516074936Subjects--Topical Terms:

519075
Psychology.
Subjects--Index Terms:

Chronic Fatigue Syndrome

Stress, Inflammation, and Mood: A Role for Leptin?
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245 1 0 $a Stress, Inflammation, and Mood: A Role for Leptin?
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300 $a 85 p.
500 $a Source: Masters Abstracts International, Volume: 83-01.
500 $a Advisor: Younger, Jarred.
502 $a Thesis (M.A.)--The University of Alabama at Birmingham, 2021.
506 $a This item must not be sold to any third party vendors.
520 $a Prior research has suggested a possible role for the proinflammatory adipokine leptin in depression. Leptin has also been associated with stress, a known predictor of depression. The purpose of this project was to investigate associations between stress, leptin, and depressed mood. We used data from a larger observational study that collected daily levels of plasma leptin and self-reported stress and depressed mood from 55 women over 25 days. Women with and without chronic fatigue syndrome (CFS) were included. We hypothesized the following: increased stress would be associated with both worsened mood and higher leptin, and that leptin would be positively associated with depressed mood. Vitamin D was also explored as a potential moderating factor. Linear mixed models were used to analyze associations between daily stress, leptin, and mood at a 1-day time lag. Results suggested an association between stress and next-day leptin, dependent on vitamin D level (p = .018). Leptin also varied by patient group depending on vitamin D (p = .018), with highest leptin observed among women with CFS and lower vitamin D (< 20 ng/mL). Overall, findings support further investigation of vitamin D in relation to stress and leptin; leptin, however, does not appear to play a substantial role in depressed mood.
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650 4 $a Mental health. $3 534751
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653 $a Stress
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