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Mechanisms of mineralization of vertebrate skeletal and dental tissues

Record Type:	Electronic resources : Monograph/item
Title/Author:	Mechanisms of mineralization of vertebrate skeletal and dental tissues/ by Irving M. Shapiro, William J. Landis.
Author:	Shapiro, Irving M.
other author:	Landis, William J.
Published:	Cham :Springer International Publishing : : 2023.,
Description:	xxiii, 497 p. :ill. (chiefly color), digital ;24 cm.
[NT 15003449]:	Introduction -- In the Beginning -- The Enigma of Edith: Free Energy, Nucleation and the Formation of Mineral -- Form and Function of Tissues that Undergo Mineralization -- Genes and Gene Networks Regulating Mineralization -- Calcium and Phosphate Ion Uptake, Distribution and Homeostasis in Cells of Vertebrate Mineralizing Tissues -- Calcium and Phosphate Ion Efflux from Cells: The Roles of Matrix Vesicles, Extracellular Vesicles, and Other Membrane-invested Transporters in Vertebrate Hard Tissue Mineralization -- Collagen-based Mineralization of Bones, Teeth and Other Vertebrate Skeletal Tissues -- The Role of Non-collagenous Proteins and Other Matrix Molecules in Vertebrate Mineralization -- Local and Systemic Regulation of Mineralization: Role of Coupling Factors, Pyrophosphate, Polyphosphates, Vitamin D, Fetuin, Matrix Gla Protein and Osteopontin -- Observations Concerning Mineral Deposition in Soft Tissues: Regulation of Aberrant Mineral Deposits -- Epilogue.
Contained By:	Springer Nature eBook
Subject:	Biomineralization. -
Online resource:	https://doi.org/10.1007/978-3-031-34304-9
ISBN:	9783031343049

Mechanisms of mineralization of vertebrate skeletal and dental tissues
Shapiro, Irving M.

Mechanisms of mineralization of vertebrate skeletal and dental tissues[electronic resource] /by Irving M. Shapiro, William J. Landis. - Cham :Springer International Publishing :2023. - xxiii, 497 p. :ill. (chiefly color), digital ;24 cm.

Introduction -- In the Beginning -- The Enigma of Edith: Free Energy, Nucleation and the Formation of Mineral -- Form and Function of Tissues that Undergo Mineralization -- Genes and Gene Networks Regulating Mineralization -- Calcium and Phosphate Ion Uptake, Distribution and Homeostasis in Cells of Vertebrate Mineralizing Tissues -- Calcium and Phosphate Ion Efflux from Cells: The Roles of Matrix Vesicles, Extracellular Vesicles, and Other Membrane-invested Transporters in Vertebrate Hard Tissue Mineralization -- Collagen-based Mineralization of Bones, Teeth and Other Vertebrate Skeletal Tissues -- The Role of Non-collagenous Proteins and Other Matrix Molecules in Vertebrate Mineralization -- Local and Systemic Regulation of Mineralization: Role of Coupling Factors, Pyrophosphate, Polyphosphates, Vitamin D, Fetuin, Matrix Gla Protein and Osteopontin -- Observations Concerning Mineral Deposition in Soft Tissues: Regulation of Aberrant Mineral Deposits -- Epilogue.

The book presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues. The focus of the book is directed toward the mineralization process, an evolutionarily conserved system in which cells synthesize a complex and unique extracellular matrix into which mineral is deposited. Regulatory control is viewed though lenses that emphasize the genetic, physical-chemical, biochemical, structural, cellular and extracellular aspects of the mineralization process as they relate to crystal nucleation, growth and maturation. Throughout the book, defects in regulation at the genetic and transcriptional levels are linked to the numerous clinical problems associated with the mineralization of bone, cartilage, tendon, tooth, and soft tissues. The book serves as a comprehensive text for basic scientists and scholars working in the many areas that comprise hard tissue research, as well as undergraduate and graduate students, postdoctoral fellows and those contemplating working in the field of biomineralization or who need a review of a specific mineralization topic. The information contained in the book is relevant for clinicians and clinical scientists in the fields of orthopaedic surgery, veterinary medicine, dentistry, endocrinology, aging and genetics.

ISBN: 9783031343049

Standard No.: 10.1007/978-3-031-34304-9doiSubjects--Topical Terms:

550365
Biomineralization.

LC Class. No.: QH512

Dewey Class. No.: 572.51

Mechanisms of mineralization of vertebrate skeletal and dental tissues
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245 1 0 $a Mechanisms of mineralization of vertebrate skeletal and dental tissues $h [electronic resource] / $c by Irving M. Shapiro, William J. Landis.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2023.
300 $a xxiii, 497 p. : $b ill. (chiefly color), digital ; $c 24 cm.
505 0 $a Introduction -- In the Beginning -- The Enigma of Edith: Free Energy, Nucleation and the Formation of Mineral -- Form and Function of Tissues that Undergo Mineralization -- Genes and Gene Networks Regulating Mineralization -- Calcium and Phosphate Ion Uptake, Distribution and Homeostasis in Cells of Vertebrate Mineralizing Tissues -- Calcium and Phosphate Ion Efflux from Cells: The Roles of Matrix Vesicles, Extracellular Vesicles, and Other Membrane-invested Transporters in Vertebrate Hard Tissue Mineralization -- Collagen-based Mineralization of Bones, Teeth and Other Vertebrate Skeletal Tissues -- The Role of Non-collagenous Proteins and Other Matrix Molecules in Vertebrate Mineralization -- Local and Systemic Regulation of Mineralization: Role of Coupling Factors, Pyrophosphate, Polyphosphates, Vitamin D, Fetuin, Matrix Gla Protein and Osteopontin -- Observations Concerning Mineral Deposition in Soft Tissues: Regulation of Aberrant Mineral Deposits -- Epilogue.
520 $a The book presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues. The focus of the book is directed toward the mineralization process, an evolutionarily conserved system in which cells synthesize a complex and unique extracellular matrix into which mineral is deposited. Regulatory control is viewed though lenses that emphasize the genetic, physical-chemical, biochemical, structural, cellular and extracellular aspects of the mineralization process as they relate to crystal nucleation, growth and maturation. Throughout the book, defects in regulation at the genetic and transcriptional levels are linked to the numerous clinical problems associated with the mineralization of bone, cartilage, tendon, tooth, and soft tissues. The book serves as a comprehensive text for basic scientists and scholars working in the many areas that comprise hard tissue research, as well as undergraduate and graduate students, postdoctoral fellows and those contemplating working in the field of biomineralization or who need a review of a specific mineralization topic. The information contained in the book is relevant for clinicians and clinical scientists in the fields of orthopaedic surgery, veterinary medicine, dentistry, endocrinology, aging and genetics.
650 0 $a Biomineralization. $3 550365
650 0 $a Skeleton. $3 543484
650 0 $a Teeth. $3 1640005
650 1 4 $a Cell Biology. $3 892383
650 2 4 $a Dentistry. $3 828971
650 2 4 $a Orthopaedics. $3 3538904
650 2 4 $a Internal Medicine. $3 858559
650 2 4 $a Medical Biochemistry. $3 892387
650 2 4 $a Life Sciences. $3 890838
700 1 $a Landis, William J. $3 3672433
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-3-031-34304-9
950 $a Medicine (SpringerNature-11650)