東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

G protein-coupled receptors = immobi...

Zhao, Xinfeng.

Linked to FindBook

Google Book

Amazon

博客來

G protein-coupled receptors = immobilization and applications in drug discovery /

Record Type:	Electronic resources : Monograph/item
Title/Author:	G protein-coupled receptors/ by Xinfeng Zhao ... [et al.].
Reminder of title:	immobilization and applications in drug discovery /
other author:	Zhao, Xinfeng.
Published:	Singapore :Springer Nature Singapore : : 2023.,
Description:	xii, 91 p. :ill., digital ;24 cm.
[NT 15003449]:	G Protein-Coupled Receptors -- Purification of G Protein-Coupled Receptors -- Oriented Immobilization of G Protein-Coupled Receptors -- Key Biochemical Aspects of Drug-Target Interactions -- Immobilized GPCRs in Drug-Receptor Interaction Analysis -- Immobilized GPCRs in Compound Screening.
Contained By:	Springer Nature eBook
Subject:	G proteins - Receptors. -
Online resource:	https://doi.org/10.1007/978-981-99-0078-7
ISBN:	9789819900787

G protein-coupled receptors = immobilization and applications in drug discovery /
G protein-coupled receptorsimmobilization and applications in drug discovery /[electronic resource] :by Xinfeng Zhao ... [et al.]. - Singapore :Springer Nature Singapore :2023. - xii, 91 p. :ill., digital ;24 cm. - SpringerBriefs in molecular science,2191-5415. - SpringerBriefs in molecular science..

G Protein-Coupled Receptors -- Purification of G Protein-Coupled Receptors -- Oriented Immobilization of G Protein-Coupled Receptors -- Key Biochemical Aspects of Drug-Target Interactions -- Immobilized GPCRs in Drug-Receptor Interaction Analysis -- Immobilized GPCRs in Compound Screening.

This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the "post-structural biology" era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.

ISBN: 9789819900787

Standard No.: 10.1007/978-981-99-0078-7doiSubjects--Topical Terms:

916557
G proteins
--Receptors.

LC Class. No.: QP552.G16 / Z43 2023

Dewey Class. No.: 572.6

G protein-coupled receptors = immobilization and applications in drug discovery /
LDR:02668nmm a2200337 a 4500 001 2315548
003 DE-He213
005 20230220075831.0
006 m d
007 cr nn 008maaau
008 230902s2023 si s 0 eng d
020 $a 9789819900787 $q (electronic bk.)
020 $a 9789819900770 $q (paper)
024 7 $a 10.1007/978-981-99-0078-7 $2 doi
035 $a 978-981-99-0078-7
040 $a GP $c GP
041 0 $a eng
050 4 $a QP552.G16 $b Z43 2023
072 7 $a PNF $2 bicssc
072 7 $a SCI013010 $2 bisacsh
072 7 $a PNF $2 thema
082 0 4 $a 572.6 $2 23
090 $a QP552.G16 $b G111 2023
245 0 0 $a G protein-coupled receptors $h [electronic resource] : $b immobilization and applications in drug discovery / $c by Xinfeng Zhao ... [et al.].
260 $a Singapore : $b Springer Nature Singapore : $b Imprint: Springer, $c 2023.
300 $a xii, 91 p. : $b ill., digital ; $c 24 cm.
490 1 $a SpringerBriefs in molecular science, $x 2191-5415
505 0 $a G Protein-Coupled Receptors -- Purification of G Protein-Coupled Receptors -- Oriented Immobilization of G Protein-Coupled Receptors -- Key Biochemical Aspects of Drug-Target Interactions -- Immobilized GPCRs in Drug-Receptor Interaction Analysis -- Immobilized GPCRs in Compound Screening.
520 $a This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the "post-structural biology" era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.
650 0 $a G proteins $x Receptors. $3 916557
650 0 $a Drug development. $3 716904
650 0 $a G proteins $x Receptors $x Effect of drugs on. $3 3627981
650 0 $a Drugs $x Design. $3 664528
650 1 4 $a Analytical Chemistry. $3 890839
650 2 4 $a Chemical Biology. $3 3602593
650 2 4 $a Medicinal Chemistry. $3 892420
650 2 4 $a Pharmaceutics. $3 3538434
700 1 $a Zhao, Xinfeng. $3 3627980
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
830 0 $a SpringerBriefs in molecular science. $3 1565866
856 4 0 $u https://doi.org/10.1007/978-981-99-0078-7
950 $a Chemistry and Materials Science (SpringerNature-11644)