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Synthetic Studies toward Ent-Kaurene...
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Billett, Brent Allen.
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Synthetic Studies toward Ent-Kaurene Natural Products: An Application of Carbon-Carbon Bond Activation in Synthesis.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Synthetic Studies toward Ent-Kaurene Natural Products: An Application of Carbon-Carbon Bond Activation in Synthesis./
作者:
Billett, Brent Allen.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 2020,
面頁冊數:
235 p.
附註:
Source: Dissertations Abstracts International, Volume: 82-01, Section: B.
Contained By:
Dissertations Abstracts International82-01B.
標題:
Organic chemistry. -
電子資源:
https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27955571
ISBN:
9798662397149
Synthetic Studies toward Ent-Kaurene Natural Products: An Application of Carbon-Carbon Bond Activation in Synthesis.
Billett, Brent Allen.
Synthetic Studies toward Ent-Kaurene Natural Products: An Application of Carbon-Carbon Bond Activation in Synthesis.
- Ann Arbor : ProQuest Dissertations & Theses, 2020 - 235 p.
Source: Dissertations Abstracts International, Volume: 82-01, Section: B.
Thesis (Ph.D.)--The University of Chicago, 2020.
This item is not available from ProQuest Dissertations & Theses.
Recent work in the area of transition metal catalyzed carbon-carbon (C-C) σ-bond activation has allowed for new strategic bond disconnection. Toward this end, the Dong lab has developed a Rh(I)-catalyzed C-C bond activation/olefin insertion strategy to access highly polycyclic scaffolds found in natural products. Of specific interest are the ent-kaurenes eriocalyxin B and isodonal. Herein, we disclose our synthetic efforts toward the family through a C-C activation method. Other key steps in the synthesis include a tandem Birch reduction propargylation reaction as well as a carbon-oxygen bond cleavage/lactonization sequence.
ISBN: 9798662397149Subjects--Topical Terms:
523952
Organic chemistry.
Subjects--Index Terms:
Carbon-carbon activation
Synthetic Studies toward Ent-Kaurene Natural Products: An Application of Carbon-Carbon Bond Activation in Synthesis.
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Recent work in the area of transition metal catalyzed carbon-carbon (C-C) σ-bond activation has allowed for new strategic bond disconnection. Toward this end, the Dong lab has developed a Rh(I)-catalyzed C-C bond activation/olefin insertion strategy to access highly polycyclic scaffolds found in natural products. Of specific interest are the ent-kaurenes eriocalyxin B and isodonal. Herein, we disclose our synthetic efforts toward the family through a C-C activation method. Other key steps in the synthesis include a tandem Birch reduction propargylation reaction as well as a carbon-oxygen bond cleavage/lactonization sequence.
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