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Maternal Weight and Diet as Protecti...

Hasken, Julie M.

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Maternal Weight and Diet as Protective Factors against the Adverse Effects of Prenatal Alcohol Exposure.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Maternal Weight and Diet as Protective Factors against the Adverse Effects of Prenatal Alcohol Exposure./
Author:	Hasken, Julie M.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2021,
Description:	195 p.
Notes:	Source: Dissertations Abstracts International, Volume: 82-12, Section: B.
Contained By:	Dissertations Abstracts International82-12B.
Subject:	Public health. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28411529
ISBN:	9798516057533

Maternal Weight and Diet as Protective Factors against the Adverse Effects of Prenatal Alcohol Exposure.
Hasken, Julie M.

Maternal Weight and Diet as Protective Factors against the Adverse Effects of Prenatal Alcohol Exposure. - Ann Arbor : ProQuest Dissertations & Theses, 2021 - 195 p.

Source: Dissertations Abstracts International, Volume: 82-12, Section: B.

Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2021.

This item must not be sold to any third party vendors.

Background: Alcohol is a known teratogen, and the prevalence of fetal alcohol spectrum disorders in the Western Cape Province of South Africa is estimated to be 17 - 28%. Yet the individual variation in child outcomes is not fully explained by the quantity, frequency, or gestational timing of prenatal alcohol exposure.Methods: We examined the influence of maternal weight on the physical and neurocognitive development of infants with and without prenatal alcohol exposure. We compared the physical growth, dysmorphology, and neurocognitive trajectories of infants to understand similarities and differences in birth measurements and rate of change, from birth to 9 months, associated with alcohol exposure and maternal weight. We also examined the role of alcohol consumption and maternal dietary intake on infant physical development in early life.Results: In this population where stunting remains a concern, higher maternal weight was associated with larger, less dysmorphic, infants with better neurodevelopmental outcomes. But the rate of change over time was similar among all infants regardless of maternal weight. Alcohol exposure consistently resulted in poorer growth and more dysmorphic infants. Most women in this population were not achieving adequate micronutrient intake for pregnant women and malnutrition remains a concern for this population. Alcohol had a direct adverse effect on maternal dietary intake.Conclusion: This research attempted to better understand maternal weight and dietary intake as factors which may mitigate some of the adverse effects of prenatal alcohol exposure in the early infancy period. Alcohol was adversely associated with maternal dietary intake and infant outcomes. Maternal weight may be somewhat protective and may partially explain some of the individual variation in infant physical and neurocognitive outcomes, but higher maternal weight does not overcome the majority of the negative, teratogenic effects of prenatal alcohol exposure. These studies affirm that there is no known safe level of alcohol exposure during pregnancy.

ISBN: 9798516057533Subjects--Topical Terms:

534748
Public health.
Subjects--Index Terms:

Fetal alcohol spectrum disorders

Maternal Weight and Diet as Protective Factors against the Adverse Effects of Prenatal Alcohol Exposure.
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500 $a Source: Dissertations Abstracts International, Volume: 82-12, Section: B.
500 $a Advisor: May, Philip A.
502 $a Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2021.
506 $a This item must not be sold to any third party vendors.
520 $a Background: Alcohol is a known teratogen, and the prevalence of fetal alcohol spectrum disorders in the Western Cape Province of South Africa is estimated to be 17 - 28%. Yet the individual variation in child outcomes is not fully explained by the quantity, frequency, or gestational timing of prenatal alcohol exposure.Methods: We examined the influence of maternal weight on the physical and neurocognitive development of infants with and without prenatal alcohol exposure. We compared the physical growth, dysmorphology, and neurocognitive trajectories of infants to understand similarities and differences in birth measurements and rate of change, from birth to 9 months, associated with alcohol exposure and maternal weight. We also examined the role of alcohol consumption and maternal dietary intake on infant physical development in early life.Results: In this population where stunting remains a concern, higher maternal weight was associated with larger, less dysmorphic, infants with better neurodevelopmental outcomes. But the rate of change over time was similar among all infants regardless of maternal weight. Alcohol exposure consistently resulted in poorer growth and more dysmorphic infants. Most women in this population were not achieving adequate micronutrient intake for pregnant women and malnutrition remains a concern for this population. Alcohol had a direct adverse effect on maternal dietary intake.Conclusion: This research attempted to better understand maternal weight and dietary intake as factors which may mitigate some of the adverse effects of prenatal alcohol exposure in the early infancy period. Alcohol was adversely associated with maternal dietary intake and infant outcomes. Maternal weight may be somewhat protective and may partially explain some of the individual variation in infant physical and neurocognitive outcomes, but higher maternal weight does not overcome the majority of the negative, teratogenic effects of prenatal alcohol exposure. These studies affirm that there is no known safe level of alcohol exposure during pregnancy.
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