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Integrated Microsystem Technologies ...

Yin, Heyu.

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Integrated Microsystem Technologies for Continuous Personal Monitoring of Airborne Pollutant Exposures.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Integrated Microsystem Technologies for Continuous Personal Monitoring of Airborne Pollutant Exposures./
作者:	Yin, Heyu.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2021,
面頁冊數:	185 p.
附註:	Source: Dissertations Abstracts International, Volume: 82-09, Section: B.
Contained By:	Dissertations Abstracts International82-09B.
標題:	Electrical engineering. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28263740
ISBN:	9798582515944

Integrated Microsystem Technologies for Continuous Personal Monitoring of Airborne Pollutant Exposures.
Yin, Heyu.

Integrated Microsystem Technologies for Continuous Personal Monitoring of Airborne Pollutant Exposures. - Ann Arbor : ProQuest Dissertations & Theses, 2021 - 185 p.

Source: Dissertations Abstracts International, Volume: 82-09, Section: B.

Thesis (Ph.D.)--Michigan State University, 2021.

This item must not be sold to any third party vendors.

Exposure to airborne pollutants, including gaseous toxins and particulate matter (PM), threaten human health and are of growing world concern. Unfortunately, the specific mechanisms behind medical conditions induced by air pollutants, as well as the socioeconomic demographics that underpin these conditions, are poorly understood. This is due, in large part, to a lack of accurate data detailing exposure profiles of individuals who suffer from acute and chronic health conditions. Air pollution levels and the activities of individuals exhibit a large degree of spatial and temporal variation, which both challenge the assessment of personal exposures. Moreover, health impacts vary significantly with chemical composition and particle size of pollutants, which further complicates effective monitoring. Utilizing a combination of microfabrication, microfluidics and electrochemical sensing technologies, this thesis research explored a microsystem solution to these challenges that can achieve high spatial resolution by providing a compact, mobile/wearable monitoring device and can achieve high temporal resolution by enabling continuous collection of personal exposure data. To create a compact monitor for multiple gaseous air pollutants, unique microfabrication procedures and electrochemical techniques were established, enabling a gas sensor array that features room temperature ionic liquid electrolyte and achieves high reliability and repeatability. In addition, a novel PM monitoring platform that uniquely employs microfluidics to achieve real-time continuous measurement was introduced, and key component technologies were developed. First, to measure PM concentrations within a compact microfluidic device, an electrochemical quantification method based on the ionic electret effect was employed for the first time using microfabricated planar electrodes and a microelectronic instrumentation module. Second, to permit real-time analysis of PM across a wide range of particle diameters, multiple generations of a microfluidic size fractionation component were developed. The first microfabricated size fractionation device realized the deterministic lateral displacement (DLD) method with a critical diameter of 2.5 µm and was successfully demonstrated to separate 10 µm and 1 µm particles with around 100% efficiency. The next size fractionation design aimed to provide multi-size separation over a wide dynamic range (~1000) of particle sizes that impact human health, down to ultrafine (nanoscale) PM. The resulting externally balanced cascade DLD concept was implemented within a mathematic model that predicts size fractionation of PM, from 10 µm to 0.01 µm, can be achieved with a minimum total device length of ~41mm using a four-section cascade. Finally, to further miniaturize the size separation device toward a monolithic implementation, an internally balanced cascade DLD design concept that can omit extra inputs and outputs was introduced and thoroughly analyzed using computational fluid dynamics simulations. The combined results of this research overcome many challenges that currently impede the desperately needed realization of personal airborne pollutant monitors offering wearable, real-time and continuous operation for unprecedented spatial and temporal resolution.

ISBN: 9798582515944Subjects--Topical Terms:

649834
Electrical engineering.
Subjects--Index Terms:

Integrated microsystem

Integrated Microsystem Technologies for Continuous Personal Monitoring of Airborne Pollutant Exposures.
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500 $a Source: Dissertations Abstracts International, Volume: 82-09, Section: B.
500 $a Advisor: Mason, Andrew J.
502 $a Thesis (Ph.D.)--Michigan State University, 2021.
506 $a This item must not be sold to any third party vendors.
520 $a Exposure to airborne pollutants, including gaseous toxins and particulate matter (PM), threaten human health and are of growing world concern. Unfortunately, the specific mechanisms behind medical conditions induced by air pollutants, as well as the socioeconomic demographics that underpin these conditions, are poorly understood. This is due, in large part, to a lack of accurate data detailing exposure profiles of individuals who suffer from acute and chronic health conditions. Air pollution levels and the activities of individuals exhibit a large degree of spatial and temporal variation, which both challenge the assessment of personal exposures. Moreover, health impacts vary significantly with chemical composition and particle size of pollutants, which further complicates effective monitoring. Utilizing a combination of microfabrication, microfluidics and electrochemical sensing technologies, this thesis research explored a microsystem solution to these challenges that can achieve high spatial resolution by providing a compact, mobile/wearable monitoring device and can achieve high temporal resolution by enabling continuous collection of personal exposure data. To create a compact monitor for multiple gaseous air pollutants, unique microfabrication procedures and electrochemical techniques were established, enabling a gas sensor array that features room temperature ionic liquid electrolyte and achieves high reliability and repeatability. In addition, a novel PM monitoring platform that uniquely employs microfluidics to achieve real-time continuous measurement was introduced, and key component technologies were developed. First, to measure PM concentrations within a compact microfluidic device, an electrochemical quantification method based on the ionic electret effect was employed for the first time using microfabricated planar electrodes and a microelectronic instrumentation module. Second, to permit real-time analysis of PM across a wide range of particle diameters, multiple generations of a microfluidic size fractionation component were developed. The first microfabricated size fractionation device realized the deterministic lateral displacement (DLD) method with a critical diameter of 2.5 µm and was successfully demonstrated to separate 10 µm and 1 µm particles with around 100% efficiency. The next size fractionation design aimed to provide multi-size separation over a wide dynamic range (~1000) of particle sizes that impact human health, down to ultrafine (nanoscale) PM. The resulting externally balanced cascade DLD concept was implemented within a mathematic model that predicts size fractionation of PM, from 10 µm to 0.01 µm, can be achieved with a minimum total device length of ~41mm using a four-section cascade. Finally, to further miniaturize the size separation device toward a monolithic implementation, an internally balanced cascade DLD design concept that can omit extra inputs and outputs was introduced and thoroughly analyzed using computational fluid dynamics simulations. The combined results of this research overcome many challenges that currently impede the desperately needed realization of personal airborne pollutant monitors offering wearable, real-time and continuous operation for unprecedented spatial and temporal resolution.
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650 4 $a Atmospheric chemistry. $3 544140
650 4 $a Environmental engineering. $3 548583
653 $a Integrated microsystem
653 $a Continuous personal monitoring
653 $a Airborne pollutant exposure
690 $a 0544
690 $a 0775
690 $a 0371
710 2 $a Michigan State University. $b Electrical Engineering - Doctor of Philosophy. $3 2094234
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