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Elemental Composition and Arsenic Speciation Analysis of Processed Seafood Products Using Atomic Spectrometric Techniques.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Elemental Composition and Arsenic Speciation Analysis of Processed Seafood Products Using Atomic Spectrometric Techniques./
Author:	Roberts, Austin A.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
Description:	328 p.
Notes:	Source: Dissertations Abstracts International, Volume: 82-02, Section: B.
Contained By:	Dissertations Abstracts International82-02B.
Subject:	Analytical chemistry. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28086510
ISBN:	9798664734751

Elemental Composition and Arsenic Speciation Analysis of Processed Seafood Products Using Atomic Spectrometric Techniques.
Roberts, Austin A.

Elemental Composition and Arsenic Speciation Analysis of Processed Seafood Products Using Atomic Spectrometric Techniques. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 328 p.

Source: Dissertations Abstracts International, Volume: 82-02, Section: B.

Thesis (Ph.D.)--State University of New York at Albany, 2020.

This item must not be sold to any third party vendors.

Arsenic (As) is a widely known toxic element that is highly ubiquitous and has been detected in soil, sediment, naturals waters, the atmosphere, and in organisms of the 5 kingdoms. The toxicity of As however, is dependent on the molecular form in which it takes as well as the route of exposure. For the general population, exposure to As mainly takes place via ingestion of food and water, which have led to numerous studies investigating As and it's various species in these matrices. Seafood is one of the major sources of dietary exposure to As and has thus led to investigations into the types of As species that exist in this food commodity, with studies showing that the relatively benign As species Aresenobetaine (AsB) tends to be the major species in fish, mollusk, and crustacean products. While there are several techniques available for As speciation analysis, the use of a liquid chromatography system coupled to a mass analyzer (e.g., LC-ICP-MS/MS or LC-MS/MS) is currently one of the most widely used techniques. Since the molecular form of As species determine the level of toxicity, it is important that samples are carefully stored and extracted so results obtained from the liquid extracts are representative of what was present in the solid material.While there are numerous studies examining As species in fresh seafood, studies investigating the effects of processing procedures (i.e., drying, canning, fermentation) on changes in the As species profile of fresh seafood are limited. This dissertation addresses several knowledge gaps and analytical challenges relevant to the study of trace elements in processed seafood products with special focus on As and its various species. Two studies were conducted and are described in this work. Firstly, to gain insight into the elemental content in dried baby shrimp products, a survey of 20 different brands/types of dried baby shrimp was conducted on products located within the Capital District of Albany, NY. Samples were homogenized and screened using High Definition X-Ray Fluorescence (HD-XRF). Samples were then subjected to acid-digestion and subsequently measured for total Arsenic and 10 other elements by atomic mass spectrometry. Further, investigations were carried out to determine the As species profile in these products by coupling liquid chromatography to inductively coupled plasma mass spectrometry (LC-ICP-MS/MS). Screening data and mass spectrometry data for elements above the detection limits of both techniques were in great agreement. While levels of total As were well above any established action level, speciation data show that the predominant species in all shrimp samples were AsB, followed by Arsenocholine (AsC), two species that are relatively non-toxic.The second study in this dissertation builds off of previous field-based work which aimed at investigating disparities of Cd, Pb, Hg, and As biomarker levels found in the Asian American community. For this dissertation, 25 archived processed seafood products were chosen and field-based XRF measurement were validated against the "gold-standard' lab-based technique, i.e., ICP-MS/MS. Additionally, chemical characterization of multiple As species was carried out giving insight into the As species profile of a broad selection of processed seafood samples. Comparison of in-situ HD-XRF measurements with those obtained by ICP-MS/MS show that the heterogenous nature of many of the samples require either in-field homogenization, which might not be feasible for large studies such as the one that collected these data, or taking multiple measurements in-field to give a more accurate estimate of average elemental content. As speciation analysis showed that in addition to AsB, AsC, Dimethylarsenate (DMA), monomethylarsenate (MMA), and the inorganic As species Arsenate and Arsenite, a total of 15 unknown As peaks were also present across the various seafood product, highlighting the diverse amount of As species that this population are exposed to via their diet.

ISBN: 9798664734751Subjects--Topical Terms:

3168300
Analytical chemistry.
Subjects--Index Terms:

Arsenic speciation

Elemental Composition and Arsenic Speciation Analysis of Processed Seafood Products Using Atomic Spectrometric Techniques.
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100 1 $a Roberts, Austin A. $0 (orcid)0000-0001-8974-7239 $3 3558778
245 1 0 $a Elemental Composition and Arsenic Speciation Analysis of Processed Seafood Products Using Atomic Spectrometric Techniques.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2020
300 $a 328 p.
500 $a Source: Dissertations Abstracts International, Volume: 82-02, Section: B.
500 $a Advisor: Parsons, Patrick J.
502 $a Thesis (Ph.D.)--State University of New York at Albany, 2020.
506 $a This item must not be sold to any third party vendors.
520 $a Arsenic (As) is a widely known toxic element that is highly ubiquitous and has been detected in soil, sediment, naturals waters, the atmosphere, and in organisms of the 5 kingdoms. The toxicity of As however, is dependent on the molecular form in which it takes as well as the route of exposure. For the general population, exposure to As mainly takes place via ingestion of food and water, which have led to numerous studies investigating As and it's various species in these matrices. Seafood is one of the major sources of dietary exposure to As and has thus led to investigations into the types of As species that exist in this food commodity, with studies showing that the relatively benign As species Aresenobetaine (AsB) tends to be the major species in fish, mollusk, and crustacean products. While there are several techniques available for As speciation analysis, the use of a liquid chromatography system coupled to a mass analyzer (e.g., LC-ICP-MS/MS or LC-MS/MS) is currently one of the most widely used techniques. Since the molecular form of As species determine the level of toxicity, it is important that samples are carefully stored and extracted so results obtained from the liquid extracts are representative of what was present in the solid material.While there are numerous studies examining As species in fresh seafood, studies investigating the effects of processing procedures (i.e., drying, canning, fermentation) on changes in the As species profile of fresh seafood are limited. This dissertation addresses several knowledge gaps and analytical challenges relevant to the study of trace elements in processed seafood products with special focus on As and its various species. Two studies were conducted and are described in this work. Firstly, to gain insight into the elemental content in dried baby shrimp products, a survey of 20 different brands/types of dried baby shrimp was conducted on products located within the Capital District of Albany, NY. Samples were homogenized and screened using High Definition X-Ray Fluorescence (HD-XRF). Samples were then subjected to acid-digestion and subsequently measured for total Arsenic and 10 other elements by atomic mass spectrometry. Further, investigations were carried out to determine the As species profile in these products by coupling liquid chromatography to inductively coupled plasma mass spectrometry (LC-ICP-MS/MS). Screening data and mass spectrometry data for elements above the detection limits of both techniques were in great agreement. While levels of total As were well above any established action level, speciation data show that the predominant species in all shrimp samples were AsB, followed by Arsenocholine (AsC), two species that are relatively non-toxic.The second study in this dissertation builds off of previous field-based work which aimed at investigating disparities of Cd, Pb, Hg, and As biomarker levels found in the Asian American community. For this dissertation, 25 archived processed seafood products were chosen and field-based XRF measurement were validated against the "gold-standard' lab-based technique, i.e., ICP-MS/MS. Additionally, chemical characterization of multiple As species was carried out giving insight into the As species profile of a broad selection of processed seafood samples. Comparison of in-situ HD-XRF measurements with those obtained by ICP-MS/MS show that the heterogenous nature of many of the samples require either in-field homogenization, which might not be feasible for large studies such as the one that collected these data, or taking multiple measurements in-field to give a more accurate estimate of average elemental content. As speciation analysis showed that in addition to AsB, AsC, Dimethylarsenate (DMA), monomethylarsenate (MMA), and the inorganic As species Arsenate and Arsenite, a total of 15 unknown As peaks were also present across the various seafood product, highlighting the diverse amount of As species that this population are exposed to via their diet.
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650 4 $a Analytical chemistry. $3 3168300
650 4 $a Environmental science. $3 677245
653 $a Arsenic speciation
653 $a Inorganic mass spectrometry
653 $a Liquid chromatography
653 $a Processed seafood
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690 $a 0768
710 2 $a State University of New York at Albany. $b Environmental Health Sciences. $3 2106377
773 0 $t Dissertations Abstracts International $g 82-02B.
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792 $a 2020
793 $a English
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