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Multiscale Characteristics of Bone T...

Nobakhti, Sabah.

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Multiscale Characteristics of Bone Toughness.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Multiscale Characteristics of Bone Toughness./
Author:	Nobakhti, Sabah.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2019,
Description:	132 p.
Notes:	Source: Dissertations Abstracts International, Volume: 81-05, Section: B.
Contained By:	Dissertations Abstracts International81-05B.
Subject:	Mechanical engineering. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=22616627
ISBN:	9781088393444

Multiscale Characteristics of Bone Toughness.
Nobakhti, Sabah.

Multiscale Characteristics of Bone Toughness. - Ann Arbor : ProQuest Dissertations & Theses, 2019 - 132 p.

Source: Dissertations Abstracts International, Volume: 81-05, Section: B.

Thesis (Ph.D.)--Northeastern University, 2019.

This item is not available from ProQuest Dissertations & Theses.

Bone has a complex hierarchical structure, resulting in elevated strength and toughness compared to a homogeneous material of the same composition. In this project, we investigated the association of material parameters across the bone hierarchical structure with the initiation, propagation and fracture toughness for mouse models of bone pathology. Initiation toughness is affected by material parameters such as the amount and the quality of collagen molecules and size of mineral particles at the nanoscale. Propagation and fracture toughness are also influenced by the amount of collagen in bone, mineral size and the degree of alignment and the AGE cross-links. We investigated thehierarchical association of material parameters in bone and showed that the energy dissipation capacity at the nanoscale, which arises from the amount and the quality of collagen molecules, size of mineral particles and collagen cross-links have the most dominant effect on mouse bone toughness.

ISBN: 9781088393444Subjects--Topical Terms:

649730
Mechanical engineering.
Subjects--Index Terms:

Collagen

Multiscale Characteristics of Bone Toughness.
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020 $a 9781088393444
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245 1 0 $a Multiscale Characteristics of Bone Toughness.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2019
300 $a 132 p.
500 $a Source: Dissertations Abstracts International, Volume: 81-05, Section: B.
500 $a Advisor: Shefelbine, Sandra J.
502 $a Thesis (Ph.D.)--Northeastern University, 2019.
506 $a This item is not available from ProQuest Dissertations & Theses.
506 $a This item must not be sold to any third party vendors.
520 $a Bone has a complex hierarchical structure, resulting in elevated strength and toughness compared to a homogeneous material of the same composition. In this project, we investigated the association of material parameters across the bone hierarchical structure with the initiation, propagation and fracture toughness for mouse models of bone pathology. Initiation toughness is affected by material parameters such as the amount and the quality of collagen molecules and size of mineral particles at the nanoscale. Propagation and fracture toughness are also influenced by the amount of collagen in bone, mineral size and the degree of alignment and the AGE cross-links. We investigated thehierarchical association of material parameters in bone and showed that the energy dissipation capacity at the nanoscale, which arises from the amount and the quality of collagen molecules, size of mineral particles and collagen cross-links have the most dominant effect on mouse bone toughness.
590 $a School code: 0160.
650 4 $a Mechanical engineering. $3 649730
650 4 $a Bioengineering. $3 657580
650 4 $a Materials science. $3 543314
653 $a Collagen
653 $a Experimental
653 $a Fracture toughness
653 $a Mineral
653 $a Mouse bone
653 $a Multiscale
690 $a 0548
690 $a 0202
690 $a 0794
710 2 $a Northeastern University. $b Mechanical and Industrial Engineering. $3 1035359
773 0 $t Dissertations Abstracts International $g 81-05B.
790 $a 0160
791 $a Ph.D.
792 $a 2019
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=22616627