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In vitro Validation of Cardiovascula...

Medero, Rafael .

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In vitro Validation of Cardiovascular MR Velocimetry Using Subject-Specific Models and Particle Image Velocimetry.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	In vitro Validation of Cardiovascular MR Velocimetry Using Subject-Specific Models and Particle Image Velocimetry./
作者:	Medero, Rafael .
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
面頁冊數:	160 p.
附註:	Source: Dissertations Abstracts International, Volume: 81-08, Section: B.
Contained By:	Dissertations Abstracts International81-08B.
標題:	Mechanical engineering. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27737539
ISBN:	9781392354506

In vitro Validation of Cardiovascular MR Velocimetry Using Subject-Specific Models and Particle Image Velocimetry.
Medero, Rafael .

In vitro Validation of Cardiovascular MR Velocimetry Using Subject-Specific Models and Particle Image Velocimetry. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 160 p.

Source: Dissertations Abstracts International, Volume: 81-08, Section: B.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2020.

This item must not be sold to any third party vendors.

Medical imaging is required for diagnosing cardiac and vascular diseases, measuring disease severity, and assessing patient response to medical and surgical therapy. Four-dimensional magnetic resonance imaging (4D Flow MRI) is a recent development in medical imaging that allows for time-resolved quantification and visualization of blood flows in the three dimensions. Despite the recent advances in 4D Flow MRI, quantitative cardiovascular fluid dynamics is still clinically underutilized, which motivates researchers in the field to develop new tools that need reliable validation. In vitro systems offer the possibility of making direct, controlled measurements, while removing patient and user-specific variations. Furthermore, in vitro validation techniques can provide a better understanding of the hemodynamics obtained in different clinical applications where spatial and temporal resolution may not be sufficient for a comprehensive analysis. Thereby, this Ph.D. thesis presents the development of in vitro experimentation using additive manufacturing (AM) and particle image velocimetry (PIV) techniques to model cardiovascular diseases and study fluid dynamics obtained with 4D Flow MRI. This work introduced the fabrication of cost-effective patient-specific vascular models to be used for PIV experiments. Then, the tomographic PIV was introduced as a volumetric technique for the in vitro validation of 4D Flow MRI, by comparing velocities between techniques that included stereo-PIV. Finally, tomographic PIV was used in a more translational research approach to investigate the effectiveness of 4D Flow MRI to assess complex flow in a patient-specific cerebral aneurysm model.

ISBN: 9781392354506Subjects--Topical Terms:

649730
Mechanical engineering.
Subjects--Index Terms:

3D printing

In vitro Validation of Cardiovascular MR Velocimetry Using Subject-Specific Models and Particle Image Velocimetry.
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