東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Quantitative Scintillation Imaging f...

Tendler, Irwin Isaac.

FindBook

Google Book

Amazon

博客來

Quantitative Scintillation Imaging for Dose Verification and Quality Assurance Testing in Radiotherapy.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Quantitative Scintillation Imaging for Dose Verification and Quality Assurance Testing in Radiotherapy./
作者:	Tendler, Irwin Isaac.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
面頁冊數:	210 p.
附註:	Source: Dissertations Abstracts International, Volume: 81-10, Section: B.
Contained By:	Dissertations Abstracts International81-10B.
標題:	Biomedical engineering. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27739079
ISBN:	9781658498883

Quantitative Scintillation Imaging for Dose Verification and Quality Assurance Testing in Radiotherapy.
Tendler, Irwin Isaac.

Quantitative Scintillation Imaging for Dose Verification and Quality Assurance Testing in Radiotherapy. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 210 p.

Source: Dissertations Abstracts International, Volume: 81-10, Section: B.

Thesis (Ph.D.)--Dartmouth College, 2020.

This item must not be sold to any third party vendors.

This work outlines the development of a novel, imaging-based, method for conducting radiotherapy dose verification and quality assurance (QA) testing of therapeutic radiation apparatus. In an effort to reduce human error and optimize workflow, light emission from plastic discs and rods was used to track surface dose of patients undergoing Total Skin Electron Therapy (TSET) and conduct QA testing of linear accelerators (linacs) / irradiators, respectively.TSET is a standard technique for treating skin lymphoma, however, the efficacy of this treatment is highly dependent on administration of uniform dose over the entire body. Thus, verifying dose homogeneity is important to ensuring therapeutic effectiveness. Conducting surface dose measurements during TSET is, unfortunately, a resource-intensive task that requires careful handling and tracking of dosimeters. The imaging system described in this work - light emitted from plastic discs attached to the skin surface is captured and converted to dose - can produce results remotely, without post-exposure processing, and in near real-time. In turn, the workflow for TSET-associated surface dosimetry is substantially streamlined when using scintillator dosimeters compared to current technologies (Optically Stimulated Luminescence Detectors, OSLD). Additionally, scintillator imaging enables an automatic method for storing dosimetric and positional treatment information without any additional operator input. These improvements were made without sacrificing measurement accuracy.In the case of QA testing of linacs or irradiators, point-measurements can often be time consuming. By imaging scintillator rods during TBI QA testing, the amount of time required to achieve results was minimized since 2D images containing dose distribution information were produced using single irradiations. This was accomplished at equivalent accuracy levels compared to OSLDs; additional comparison testing with ionization chambers was used to further verify accuracy of scintillator measurements. QA testing of MRI-linacs is all the more complicated since use of standard motorized devices in the presence of a strong magnetic field is not possible. Thus, scintillating rods were adapted for use in daily QA testing of an MRI-linac; this technology was able to complete AAPM TG-142 tests accurately and with sufficient sensitivity.

ISBN: 9781658498883Subjects--Topical Terms:

535387
Biomedical engineering.
Subjects--Index Terms:

Medical physics

Quantitative Scintillation Imaging for Dose Verification and Quality Assurance Testing in Radiotherapy.
LDR:03499nmm a2200349 4500 001 2270199
005 20200921070752.5
008 220629s2020 ||||||||||||||||| ||eng d
020 $a 9781658498883
035 $a (MiAaPQ)AAI27739079
035 $a AAI27739079
040 $a MiAaPQ $c MiAaPQ
100 1 $a Tendler, Irwin Isaac. $3 3547568
245 1 0 $a Quantitative Scintillation Imaging for Dose Verification and Quality Assurance Testing in Radiotherapy.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2020
300 $a 210 p.
500 $a Source: Dissertations Abstracts International, Volume: 81-10, Section: B.
500 $a Advisor: Gladstone, David J.
502 $a Thesis (Ph.D.)--Dartmouth College, 2020.
506 $a This item must not be sold to any third party vendors.
520 $a This work outlines the development of a novel, imaging-based, method for conducting radiotherapy dose verification and quality assurance (QA) testing of therapeutic radiation apparatus. In an effort to reduce human error and optimize workflow, light emission from plastic discs and rods was used to track surface dose of patients undergoing Total Skin Electron Therapy (TSET) and conduct QA testing of linear accelerators (linacs) / irradiators, respectively.TSET is a standard technique for treating skin lymphoma, however, the efficacy of this treatment is highly dependent on administration of uniform dose over the entire body. Thus, verifying dose homogeneity is important to ensuring therapeutic effectiveness. Conducting surface dose measurements during TSET is, unfortunately, a resource-intensive task that requires careful handling and tracking of dosimeters. The imaging system described in this work - light emitted from plastic discs attached to the skin surface is captured and converted to dose - can produce results remotely, without post-exposure processing, and in near real-time. In turn, the workflow for TSET-associated surface dosimetry is substantially streamlined when using scintillator dosimeters compared to current technologies (Optically Stimulated Luminescence Detectors, OSLD). Additionally, scintillator imaging enables an automatic method for storing dosimetric and positional treatment information without any additional operator input. These improvements were made without sacrificing measurement accuracy.In the case of QA testing of linacs or irradiators, point-measurements can often be time consuming. By imaging scintillator rods during TBI QA testing, the amount of time required to achieve results was minimized since 2D images containing dose distribution information were produced using single irradiations. This was accomplished at equivalent accuracy levels compared to OSLDs; additional comparison testing with ionization chambers was used to further verify accuracy of scintillator measurements. QA testing of MRI-linacs is all the more complicated since use of standard motorized devices in the presence of a strong magnetic field is not possible. Thus, scintillating rods were adapted for use in daily QA testing of an MRI-linac; this technology was able to complete AAPM TG-142 tests accurately and with sufficient sensitivity.
590 $a School code: 0059.
650 4 $a Biomedical engineering. $3 535387
650 4 $a Medical imaging. $3 3172799
653 $a Medical physics
653 $a Optical
653 $a Quality assurance
653 $a Scintillator
690 $a 0541
690 $a 0574
710 2 $a Dartmouth College. $b Engineering. $3 1057396
773 0 $t Dissertations Abstracts International $g 81-10B.
790 $a 0059
791 $a Ph.D.
792 $a 2020
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27739079