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The Detection of Cocaine in Oral Flu...

Ahmed, Yasmine.

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The Detection of Cocaine in Oral Fluid Using Ultraviolet Resonance Raman Spectroscopy.

Record Type:	Electronic resources : Monograph/item
Title/Author:	The Detection of Cocaine in Oral Fluid Using Ultraviolet Resonance Raman Spectroscopy./
Author:	Ahmed, Yasmine.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2018,
Description:	55 p.
Notes:	Source: Masters Abstracts International, Volume: 79-11.
Contained By:	Masters Abstracts International79-11.
Subject:	Analytical chemistry. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10810451
ISBN:	9780355957129

The Detection of Cocaine in Oral Fluid Using Ultraviolet Resonance Raman Spectroscopy.
Ahmed, Yasmine.

The Detection of Cocaine in Oral Fluid Using Ultraviolet Resonance Raman Spectroscopy. - Ann Arbor : ProQuest Dissertations & Theses, 2018 - 55 p.

Source: Masters Abstracts International, Volume: 79-11.

Thesis (M.S.)--State University of New York at Albany, 2018.

This item must not be added to any third party search indexes.

Drug abuse has become a worldwide epidemic and is correlated to various serious health problems as well as increased rates of crime; thus, detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. To date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this study, the possibility of using Raman spectroscopy to detect cocaine in oral fluid without pretreatment of samples was investigated. It was found that normal Raman spectroscopy at an excitation wavelength of 407 nm produced no cocaine signal while use of Raman spectroscopy at an excitation wavelength of 785 nm only produced a cocaine signal at high cocaine concentrations. Analysis using excitation wavelengths in the ultraviolet range of light (240 nm and 200 nm), however, allowed for the detection of cocaine in oral fluid down to a detection limit of 10 µg/mL without the need for sample pretreatment.

ISBN: 9780355957129Subjects--Topical Terms:

3168300
Analytical chemistry.

The Detection of Cocaine in Oral Fluid Using Ultraviolet Resonance Raman Spectroscopy.
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245 1 4 $a The Detection of Cocaine in Oral Fluid Using Ultraviolet Resonance Raman Spectroscopy.
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300 $a 55 p.
500 $a Source: Masters Abstracts International, Volume: 79-11.
500 $a Publisher info.: Dissertation/Thesis.
500 $a Advisor: Lednev, Igor K.
502 $a Thesis (M.S.)--State University of New York at Albany, 2018.
506 $a This item must not be added to any third party search indexes.
506 $a This item must not be sold to any third party vendors.
520 $a Drug abuse has become a worldwide epidemic and is correlated to various serious health problems as well as increased rates of crime; thus, detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. To date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this study, the possibility of using Raman spectroscopy to detect cocaine in oral fluid without pretreatment of samples was investigated. It was found that normal Raman spectroscopy at an excitation wavelength of 407 nm produced no cocaine signal while use of Raman spectroscopy at an excitation wavelength of 785 nm only produced a cocaine signal at high cocaine concentrations. Analysis using excitation wavelengths in the ultraviolet range of light (240 nm and 200 nm), however, allowed for the detection of cocaine in oral fluid down to a detection limit of 10 µg/mL without the need for sample pretreatment.
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