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The Influence of Inflammation on Sle...

Dolsen, Michael Robert.

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The Influence of Inflammation on Sleep, Circadian Functioning, and Risk among Adolescents with an Evening Circadian Preference.

Record Type:	Electronic resources : Monograph/item
Title/Author:	The Influence of Inflammation on Sleep, Circadian Functioning, and Risk among Adolescents with an Evening Circadian Preference./
Author:	Dolsen, Michael Robert.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
Description:	25 p.
Notes:	Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
Contained By:	Dissertations Abstracts International81-04B.
Subject:	Clinical psychology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=13860948
ISBN:	9781085780469

The Influence of Inflammation on Sleep, Circadian Functioning, and Risk among Adolescents with an Evening Circadian Preference.
Dolsen, Michael Robert.

The Influence of Inflammation on Sleep, Circadian Functioning, and Risk among Adolescents with an Evening Circadian Preference. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 25 p.

Source: Dissertations Abstracts International, Volume: 81-04, Section: B.

Thesis (Ph.D.)--University of California, Berkeley, 2020.

This item must not be sold to any third party vendors.

Background. Adolescence is associated with a shift toward an evening circadian preference, which is linked to increased risk across health domains. This study examined the influence of inflammation on sleep, circadian functioning, and health at pretreatment and following participation in a psychosocial intervention targeting sleep and health.Method. Participants were 165 (96 female, average age = 14.7 years) adolescents randomized to receive 6-sessions of a psychosocial intervention targeting sleep and health. Sleep and circadian outcomes included weeknight total sleep time (TST), weeknight bedtime, and the Children's Morningness-Eveningness Preferences Scale. Health domains included emotional, cognitive, behavioral, social, and physical health. Sleep, circadian, and health outcomes were assessed at pretreatment, posttreatment, 6-month follow-up, and 12-month follow-up. Inflammatory markers were soluble tumor necrosis factor receptor 2 (sTNF-R2), interleukin (IL)-6, and C-reactive protein (CRP) measured at pretreatment.Results. At pretreatment, shorter TST was associated with more emotional domain risk among adolescents with higher CRP. For adolescents with lower IL-6 at pretreatment, a greater evening circadian preference was associated with more behavioral risk. Inflammation also influenced treatment effects. Lower pretreatment sTNF-R2 was related to a decrease in self-reported evening circadian preference following treatment and through follow-up. Lower pretreatment IL-6 was associated with reduced behavioral and physical domain risk following treatment and through follow-up.Conclusions. These findings support a growing body of literature showing that biological factors such as inflammation may influence sensitivity to positive and negative experiences on outcomes across key domains of health during adolescence.

ISBN: 9781085780469Subjects--Topical Terms:

524863
Clinical psychology.
Subjects--Index Terms:

Influence of inflammation

The Influence of Inflammation on Sleep, Circadian Functioning, and Risk among Adolescents with an Evening Circadian Preference.
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520 $a Background. Adolescence is associated with a shift toward an evening circadian preference, which is linked to increased risk across health domains. This study examined the influence of inflammation on sleep, circadian functioning, and health at pretreatment and following participation in a psychosocial intervention targeting sleep and health.Method. Participants were 165 (96 female, average age = 14.7 years) adolescents randomized to receive 6-sessions of a psychosocial intervention targeting sleep and health. Sleep and circadian outcomes included weeknight total sleep time (TST), weeknight bedtime, and the Children's Morningness-Eveningness Preferences Scale. Health domains included emotional, cognitive, behavioral, social, and physical health. Sleep, circadian, and health outcomes were assessed at pretreatment, posttreatment, 6-month follow-up, and 12-month follow-up. Inflammatory markers were soluble tumor necrosis factor receptor 2 (sTNF-R2), interleukin (IL)-6, and C-reactive protein (CRP) measured at pretreatment.Results. At pretreatment, shorter TST was associated with more emotional domain risk among adolescents with higher CRP. For adolescents with lower IL-6 at pretreatment, a greater evening circadian preference was associated with more behavioral risk. Inflammation also influenced treatment effects. Lower pretreatment sTNF-R2 was related to a decrease in self-reported evening circadian preference following treatment and through follow-up. Lower pretreatment IL-6 was associated with reduced behavioral and physical domain risk following treatment and through follow-up.Conclusions. These findings support a growing body of literature showing that biological factors such as inflammation may influence sensitivity to positive and negative experiences on outcomes across key domains of health during adolescence.
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