Histone deacetylase inhibitors in co...
Ganai, Shabir Ahmad.

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  • Histone deacetylase inhibitors in combinatorial anticancer therapy
  • Record Type: Electronic resources : Monograph/item
    Title/Author: Histone deacetylase inhibitors in combinatorial anticancer therapy/ by Shabir Ahmad Ganai.
    Author: Ganai, Shabir Ahmad.
    Published: Singapore :Springer Singapore : : 2020.,
    Description: xvii, 258 p. :ill. (some col.), digital ;24 cm.
    [NT 15003449]: Chapter 1_Epigenetic modifying enzymes. -Chapter 2_Epigenetic modifying enzymes implicated in cancer. -Chapter 3_Classification of histone deacetylases (HDACs) -Chapter 4_Implications of 18 HDAC isoforms in therapeutically monotonous cancers. -Chapter 5_Possible Mechanisms of HDACs in Cancer development -- Chapter 6_Different strategies employed for circumventing cancer resistance (chemo and radio) and mitigating toxicity. -Chapter 7_Limitations of conventional therapeutic regimens in treating cancer. -Chapter 8_Overview of epidrugs with special emphasis on HDAC inhibitors (HDACi) -- Chapter 9_HDAC inhibitors as promising epidrugs for treating cancer. -Chapter 10_ HDAC inhibitors in anticancer monotherapy. -Chapter 11_Distinct groups of histone deacetylase inhibitors (HDACi) based on the structural distinction, HDACs targeted. -Chapter 12_Limited efficacy of HDAC inhibitor-based monotherapy. -Chapter 13_Resistance mechanisms generated by cancer cells against HDACi based monotherapy. -Chapter 14_ Toxicity issue of HDAC inhibitor based monotherapy. -Chapter 15_Combinatorial therapeutic strategies of HDACi. -Chapter 16_Designing Selective HDACi using computational and medicinal chemistry approach. -Chapter 17. Current therapeutic challenges and future directions.
    Contained By: Springer Nature eBook
    Subject: Histone deacetylase - Inhibitors. -
    Online resource: https://doi.org/10.1007/978-981-15-8179-3
    ISBN: 9789811581793
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