東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Molecular targeted radiosensitizers ...

Willers, Henning.

FindBook

Google Book

Amazon

博客來

Molecular targeted radiosensitizers = opportunities and challenges /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Molecular targeted radiosensitizers/ edited by Henning Willers, Iris Eke.
其他題名:	opportunities and challenges /
其他作者:	Willers, Henning.
出版者:	Cham :Springer International Publishing : : 2020.,
面頁冊數:	xi, 364 p. :ill., digital ;24 cm.
內容註:	Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance -- Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index.
Contained By:	Springer Nature eBook
標題:	Cancer - Radiotherapy -
電子資源:	https://doi.org/10.1007/978-3-030-49701-9
ISBN:	9783030497019

Molecular targeted radiosensitizers = opportunities and challenges /
Molecular targeted radiosensitizersopportunities and challenges /[electronic resource] :edited by Henning Willers, Iris Eke. - Cham :Springer International Publishing :2020. - xi, 364 p. :ill., digital ;24 cm. - Cancer drug discovery and development,2196-9906. - Cancer drug discovery and development..

Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance -- Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index.

Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.

ISBN: 9783030497019

Standard No.: 10.1007/978-3-030-49701-9doiSubjects--Topical Terms:

3526089
Cancer
--Radiotherapy

LC Class. No.: RC271.R3 / M654 2020

Dewey Class. No.: 616.9940642

Molecular targeted radiosensitizers = opportunities and challenges /
LDR:03366nmm a2200337 a 4500 001 2256077
003 DE-He213
005 20201229094639.0
006 m d
007 cr nn 008maaau
008 220420s2020 sz s 0 eng d
020 $a 9783030497019 $q (electronic bk.)
020 $a 9783030497002 $q (paper)
024 7 $a 10.1007/978-3-030-49701-9 $2 doi
035 $a 978-3-030-49701-9
040 $a GP $c GP
041 0 $a eng
050 4 $a RC271.R3 $b M654 2020
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 616.9940642 $2 23
090 $a RC271.R3 $b M718 2020
245 0 0 $a Molecular targeted radiosensitizers $h [electronic resource] : $b opportunities and challenges / $c edited by Henning Willers, Iris Eke.
260 $a Cham : $b Springer International Publishing : $b Imprint: Humana, $c 2020.
300 $a xi, 364 p. : $b ill., digital ; $c 24 cm.
490 1 $a Cancer drug discovery and development, $x 2196-9906
505 0 $a Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance -- Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index.
520 $a Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.
650 0 $a Cancer $x Radiotherapy $x Molecular aspects. $3 3526089
650 0 $a Radiation-sensitizing agents. $3 907969
650 1 4 $a Cancer Research. $3 891172
650 2 4 $a Radiotherapy. $3 862372
650 2 4 $a Pharmacology/Toxicology. $3 890953
700 1 $a Willers, Henning. $3 3526087
700 1 $a Eke, Iris. $3 3526088
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
830 0 $a Cancer drug discovery and development. $3 1565408
856 4 0 $u https://doi.org/10.1007/978-3-030-49701-9
950 $a Medicine (SpringerNature-11650)