Phase I oncology drug development
Yap, Timothy A.

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  • Phase I oncology drug development
  • 紀錄類型: 書目-電子資源 : Monograph/item
    正題名/作者: Phase I oncology drug development/ edited by Timothy A. Yap, Jordi Rodon, David S. Hong.
    其他作者: Yap, Timothy A.
    出版者: Cham :Springer International Publishing : : 2020.,
    面頁冊數: x, 352 p. :ill., digital ;24 cm.
    內容註: Paradigm shift in oncology drug development -- Practicalities in setting up phase I trials -- Optimizing the preclinical development of antitumor agents for entry into phase I trials -- Considerations for the development of novel chemotherapies in phase I trials -- Considerations for the development of novel targeted agents in phase I trials -- Development of immunotherapeutic strategies in early phase clinical trials -- Assessment of radiotherapeutic strategies in phase I trials -- Development of combinatorial strategies in phase I trials -- Novel trial designs for early phase clinical trials -- Incorporating pharmacokinetic strategies for phase I trials -- Development of pharmacodynamic biomarkers for phase I trials -- Efficacy considerations for Phase I trials -- Incorporating precision medicine into Phase I clinical trials -- Molecular profiling of patients for clinical trials -- Incorporating circulating biomarkers into clinical trials -- Statistical considerations for early phase clinical trials -- Lessons from hematology for solid tumor drug development.
    Contained By: Springer Nature eBook
    標題: Antineoplastic agents - Design. -
    電子資源: https://doi.org/10.1007/978-3-030-47682-3
    ISBN: 9783030476823
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