東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Circulating tumor cells in breast ca...

Pineiro, Roberto.

FindBook

Google Book

Amazon

博客來

Circulating tumor cells in breast cancer metastatic disease

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Circulating tumor cells in breast cancer metastatic disease/ edited by Roberto Pineiro.
其他作者:	Pineiro, Roberto.
出版者:	Cham :Springer International Publishing : : 2020.,
面頁冊數:	xv, 167 p. :ill., digital ;24 cm.
內容註:	Preface -- Introduction - Biology of Breast Cancer Metastasis and Importance of the Analysis of CTCs -- Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis -- Disseminated Tumor Cells and Dormancy in Breast Cancer Progression -- Methodology for the Isolation and Analysis of CTCs -- Advances in the Characterization of Circulating Tumor Cells in Metastatic Breast Cancer: Single Cell Analyses and Interactions, and Patient-derived Models for Drug Testing -- Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs -- Relevance of CTC Clusters in Breast Cancer Metastasis -- Epigenetics of Circulating Tumor Cells in Breast Cancer -- Circulating Tumor Cells: Applications for Early Breast Cancer -- Clinical Relevance and Therapeutic Application of CTCs in Advanced Breast Cancer.
Contained By:	Springer eBooks
標題:	Breast - Cancer -
電子資源:	https://doi.org/10.1007/978-3-030-35805-1
ISBN:	9783030358051

Circulating tumor cells in breast cancer metastatic disease
Circulating tumor cells in breast cancer metastatic disease[electronic resource] /edited by Roberto Pineiro. - Cham :Springer International Publishing :2020. - xv, 167 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.12200065-2598 ;. - Advances in experimental medicine and biology ;v.1220..

Preface -- Introduction - Biology of Breast Cancer Metastasis and Importance of the Analysis of CTCs -- Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis -- Disseminated Tumor Cells and Dormancy in Breast Cancer Progression -- Methodology for the Isolation and Analysis of CTCs -- Advances in the Characterization of Circulating Tumor Cells in Metastatic Breast Cancer: Single Cell Analyses and Interactions, and Patient-derived Models for Drug Testing -- Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs -- Relevance of CTC Clusters in Breast Cancer Metastasis -- Epigenetics of Circulating Tumor Cells in Breast Cancer -- Circulating Tumor Cells: Applications for Early Breast Cancer -- Clinical Relevance and Therapeutic Application of CTCs in Advanced Breast Cancer.

This book compiles the latest research and key findings about the role of circulating tumor cells (CTCs) in Breast Cancer progression, both from the research and clinical standpoint. Based on latest advancements, the content of the book is set out to provide a clear overview about the biology and use of CTCs as a tool for the monitoring and management of breast cancer patients. This work covers basic concepts about the process of metastasis, the biology of CTCs and their potential applications as a biomarker in breast cancer. It will enable readers to delve into the process of epithelial-mesenchymal plasticity (EMP), mechanisms and clinical implications of tumor cell dormancy and minimal residual disease, and into the phenotypical and molecular heterogeneity of CTCs and CTC clusters, including the epigenetic characterization of CTCs. Readers will find out about the key technologies used for the isolation of CTCs as well as the latest advances towards the characterization of CTCs, involving single cell analyses and patient-derived models. It will discuss the evidences about the use of CTCs as a tool to monitor breast cancer progression and therapy response, as well as to unravel mechanisms of resistance to therapy and to identify new therapeutic targets favoring the development of novel anticancer drugs. Lastly, it will discuss ongoing clinical trials and try to foresee the future of CTCs in terms of clinical application and implementation in the clinical routine. The topic of this book is particularly relevant for cancer researchers and oncologist with an interest in the field, looking to refresh or to broaden their knowledge and understanding about the use of CTCs as a diagnostic biomarker in breast cancer.

ISBN: 9783030358051

Standard No.: 10.1007/978-3-030-35805-1doiSubjects--Topical Terms:

2160346
Breast
--Cancer

LC Class. No.: RC280.B8 / C573 2020

Dewey Class. No.: 616.99449

Circulating tumor cells in breast cancer metastatic disease
LDR:03689nmm a2200337 a 4500 001 2217524
003 DE-He213
005 20200810172740.0
006 m d
007 cr nn 008maaau
008 201120s2020 sz s 0 eng d
020 $a 9783030358051 $q (electronic bk.)
020 $a 9783030358044 $q (paper)
024 7 $a 10.1007/978-3-030-35805-1 $2 doi
035 $a 978-3-030-35805-1
040 $a GP $c GP
041 0 $a eng
050 4 $a RC280.B8 $b C573 2020
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 616.99449 $2 23
090 $a RC280.B8 $b C578 2020
245 0 0 $a Circulating tumor cells in breast cancer metastatic disease $h [electronic resource] / $c edited by Roberto Pineiro.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2020.
300 $a xv, 167 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.1220
505 0 $a Preface -- Introduction - Biology of Breast Cancer Metastasis and Importance of the Analysis of CTCs -- Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis -- Disseminated Tumor Cells and Dormancy in Breast Cancer Progression -- Methodology for the Isolation and Analysis of CTCs -- Advances in the Characterization of Circulating Tumor Cells in Metastatic Breast Cancer: Single Cell Analyses and Interactions, and Patient-derived Models for Drug Testing -- Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs -- Relevance of CTC Clusters in Breast Cancer Metastasis -- Epigenetics of Circulating Tumor Cells in Breast Cancer -- Circulating Tumor Cells: Applications for Early Breast Cancer -- Clinical Relevance and Therapeutic Application of CTCs in Advanced Breast Cancer.
520 $a This book compiles the latest research and key findings about the role of circulating tumor cells (CTCs) in Breast Cancer progression, both from the research and clinical standpoint. Based on latest advancements, the content of the book is set out to provide a clear overview about the biology and use of CTCs as a tool for the monitoring and management of breast cancer patients. This work covers basic concepts about the process of metastasis, the biology of CTCs and their potential applications as a biomarker in breast cancer. It will enable readers to delve into the process of epithelial-mesenchymal plasticity (EMP), mechanisms and clinical implications of tumor cell dormancy and minimal residual disease, and into the phenotypical and molecular heterogeneity of CTCs and CTC clusters, including the epigenetic characterization of CTCs. Readers will find out about the key technologies used for the isolation of CTCs as well as the latest advances towards the characterization of CTCs, involving single cell analyses and patient-derived models. It will discuss the evidences about the use of CTCs as a tool to monitor breast cancer progression and therapy response, as well as to unravel mechanisms of resistance to therapy and to identify new therapeutic targets favoring the development of novel anticancer drugs. Lastly, it will discuss ongoing clinical trials and try to foresee the future of CTCs in terms of clinical application and implementation in the clinical routine. The topic of this book is particularly relevant for cancer researchers and oncologist with an interest in the field, looking to refresh or to broaden their knowledge and understanding about the use of CTCs as a diagnostic biomarker in breast cancer.
650 0 $a Breast $x Cancer $x Molecular aspects. $3 2160346
650 1 4 $a Cancer Research. $3 891172
650 2 4 $a Molecular Medicine. $3 890952
650 2 4 $a Biomedical Engineering/Biotechnology. $3 2162071
650 2 4 $a Stem Cells. $3 580755
700 1 $a Pineiro, Roberto. $3 3450806
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v v.1220. $3 3450807
856 4 0 $u https://doi.org/10.1007/978-3-030-35805-1
950 $a Biomedical and Life Sciences (Springer-11642)