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Development of Advanced Multifunctio...

Kim, Eric.

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Development of Advanced Multifunctional Neural Interface Devices.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Development of Advanced Multifunctional Neural Interface Devices./
Author:	Kim, Eric.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2018,
Description:	195 p.
Notes:	Source: Dissertations Abstracts International, Volume: 79-11, Section: B.
Contained By:	Dissertations Abstracts International79-11B.
Subject:	Neurosciences. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10189959
ISBN:	9780355826678

Development of Advanced Multifunctional Neural Interface Devices.
Kim, Eric.

Development of Advanced Multifunctional Neural Interface Devices. - Ann Arbor : ProQuest Dissertations & Theses, 2018 - 195 p.

Source: Dissertations Abstracts International, Volume: 79-11, Section: B.

Thesis (Ph.D.)--Wayne State University, 2018.

This item is not available from ProQuest Dissertations & Theses.

The fine micro-architecture of neural tissue complicates efforts to create neural interface hardware capable of high resolution input and output from neural circuitry. Microtechnology provides a unique opportunity to create neural interface hardware with efficiency and precision that is capable of utilizing multiple modalities for recording and stimulating neural activity. In this thesis work, we investigate the application of silicon-parylene hybrid micro-structures for the creation of novel microtechnology based neural interface devices capable of electrical, chemical, and optical interrogation of neural tissue activity. Specifically, we explore the creation of the following devices: 1) microstructured neural probes with microfluidic delivery for chronic suppression of tissue response, 2) integration of optics including optical fibers and waveguides into neural probes, and 3) development of a mechanically tunable microfabricated cochlear implant probe for use in rats.

ISBN: 9780355826678Subjects--Topical Terms:

588700
Neurosciences.

Development of Advanced Multifunctional Neural Interface Devices.
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245 1 0 $a Development of Advanced Multifunctional Neural Interface Devices.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2018
300 $a 195 p.
500 $a Source: Dissertations Abstracts International, Volume: 79-11, Section: B.
500 $a Publisher info.: Dissertation/Thesis.
500 $a Advisor: Xu, Yong.
502 $a Thesis (Ph.D.)--Wayne State University, 2018.
506 $a This item is not available from ProQuest Dissertations & Theses.
506 $a This item must not be sold to any third party vendors.
520 $a The fine micro-architecture of neural tissue complicates efforts to create neural interface hardware capable of high resolution input and output from neural circuitry. Microtechnology provides a unique opportunity to create neural interface hardware with efficiency and precision that is capable of utilizing multiple modalities for recording and stimulating neural activity. In this thesis work, we investigate the application of silicon-parylene hybrid micro-structures for the creation of novel microtechnology based neural interface devices capable of electrical, chemical, and optical interrogation of neural tissue activity. Specifically, we explore the creation of the following devices: 1) microstructured neural probes with microfluidic delivery for chronic suppression of tissue response, 2) integration of optics including optical fibers and waveguides into neural probes, and 3) development of a mechanically tunable microfabricated cochlear implant probe for use in rats.
590 $a School code: 0254.
650 4 $a Neurosciences. $3 588700
650 4 $a Engineering. $3 586835
650 4 $a Nanoscience. $3 587832
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710 2 $a Wayne State University. $b Biomedical Engineering. $3 1057465
773 0 $t Dissertations Abstracts International $g 79-11B.
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793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10189959