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Inhalation Exposure and Respiratory ...

Ollier, Katherine.

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Inhalation Exposure and Respiratory Protection of Home Healthcare Workers Administering Aerosolized Medications (Simulation Study).

Record Type:	Electronic resources : Monograph/item
Title/Author:	Inhalation Exposure and Respiratory Protection of Home Healthcare Workers Administering Aerosolized Medications (Simulation Study)./
Author:	Ollier, Katherine.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2018,
Description:	29 p.
Notes:	Source: Masters Abstracts International, Volume: 58-03.
Contained By:	Masters Abstracts International58-03(E).
Subject:	Environmental health. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=11011020
ISBN:	9780438648791

Inhalation Exposure and Respiratory Protection of Home Healthcare Workers Administering Aerosolized Medications (Simulation Study).
Ollier, Katherine.

Inhalation Exposure and Respiratory Protection of Home Healthcare Workers Administering Aerosolized Medications (Simulation Study). - Ann Arbor : ProQuest Dissertations & Theses, 2018 - 29 p.

Source: Masters Abstracts International, Volume: 58-03.

Thesis (M.S.)--University of Cincinnati, 2018.

There is little information regarding the aerosol exposure produced by a medical nebulizer and the factors that affect the exposure, especially when the treatment is performed in a patient home environment. Home healthcare workers (HHWs) is a rapidly growing work population often exposed to significant aerosol hazards. In this study, we designed a simulated environment to measure the inhalation aerosol exposure of a HHW under different conditions. We also determined the relative contributions of different factors on the aerosol reduction in the exposure chamber simulating a patient's bedroom. Those conditions included room air exchange rate, proximity to the patient, and the patient breathing rate. Additionally, the performance of different respiratory protective devices typically worn by a HHW, a surgical mask and N95 filtering facepiece respirator (FFR), was evaluated. NaCl was used as a surrogate for nebulizer-aerosolized medication. The particle concentration in the breathing zone of an unprotected worker ranged from 7,118 to 284,600 cm-3. For unprotected HHWs, ventilation was the most effective mean to reduce the occupational exposure to medical aerosols produced during nebulizer-based treatment. An increase in air exchange rate from 0 (calm air) to 5 h -1 significantly reduced the exposure; however, further increase from 5 to 17 h-1 provided only a minor decrease in the particle concentration. Consequently, there is no evidence that patient homes should need an extremely efficient ventilation in order to mitigate the HHW's exposure to the nebulizer-produced medications. In homes with no ventilation, a HHW standing at least 24 inches from the particle source could have significantly lower exposure risk. Increase in patient breathing flow rate was found to reduce the inhalation aerosol exposure. However, this factor cannot be controlled, which makes this effect of no practical implication for controlling the HHW's exposure. Wearing respiratory protection devices was found to be the most efficient way to reduce aerosol exposure. As expected, an N95 FFR with a proper seal was about 20 times more efficient than a surgical mask.

ISBN: 9780438648791Subjects--Topical Terms:

543032
Environmental health.

Inhalation Exposure and Respiratory Protection of Home Healthcare Workers Administering Aerosolized Medications (Simulation Study).
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520 $a There is little information regarding the aerosol exposure produced by a medical nebulizer and the factors that affect the exposure, especially when the treatment is performed in a patient home environment. Home healthcare workers (HHWs) is a rapidly growing work population often exposed to significant aerosol hazards. In this study, we designed a simulated environment to measure the inhalation aerosol exposure of a HHW under different conditions. We also determined the relative contributions of different factors on the aerosol reduction in the exposure chamber simulating a patient's bedroom. Those conditions included room air exchange rate, proximity to the patient, and the patient breathing rate. Additionally, the performance of different respiratory protective devices typically worn by a HHW, a surgical mask and N95 filtering facepiece respirator (FFR), was evaluated. NaCl was used as a surrogate for nebulizer-aerosolized medication. The particle concentration in the breathing zone of an unprotected worker ranged from 7,118 to 284,600 cm-3. For unprotected HHWs, ventilation was the most effective mean to reduce the occupational exposure to medical aerosols produced during nebulizer-based treatment. An increase in air exchange rate from 0 (calm air) to 5 h -1 significantly reduced the exposure; however, further increase from 5 to 17 h-1 provided only a minor decrease in the particle concentration. Consequently, there is no evidence that patient homes should need an extremely efficient ventilation in order to mitigate the HHW's exposure to the nebulizer-produced medications. In homes with no ventilation, a HHW standing at least 24 inches from the particle source could have significantly lower exposure risk. Increase in patient breathing flow rate was found to reduce the inhalation aerosol exposure. However, this factor cannot be controlled, which makes this effect of no practical implication for controlling the HHW's exposure. Wearing respiratory protection devices was found to be the most efficient way to reduce aerosol exposure. As expected, an N95 FFR with a proper seal was about 20 times more efficient than a surgical mask.
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