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Transcriptome-based Gene Networks fo...

Gupta, Chirag.

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Transcriptome-based Gene Networks for Systems-level Analysis of Plant Gene Functions.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Transcriptome-based Gene Networks for Systems-level Analysis of Plant Gene Functions./
作者:	Gupta, Chirag.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2017,
面頁冊數:	154 p.
附註:	Source: Dissertation Abstracts International, Volume: 79-02(E), Section: B.
Contained By:	Dissertation Abstracts International79-02B(E).
標題:	Bioinformatics. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10636543
ISBN:	9780355353648

Transcriptome-based Gene Networks for Systems-level Analysis of Plant Gene Functions.
Gupta, Chirag.

Transcriptome-based Gene Networks for Systems-level Analysis of Plant Gene Functions. - Ann Arbor : ProQuest Dissertations & Theses, 2017 - 154 p.

Source: Dissertation Abstracts International, Volume: 79-02(E), Section: B.

Thesis (Ph.D.)--University of Arkansas, 2017.

Present day genomic technologies are evolving at an unprecedented rate, allowing interrogation of cellular activities with increasing breadth and depth. However, we know very little about how the genome functions and what the identified genes do. The lack of functional annotations of genes greatly limits the post-analytical interpretation of new high throughput genomic datasets. For plant biologists, the problem is much severe. Less than 50% of all the identified genes in the model plant Arabidopsis thaliana, and only about 20% of all genes in the crop model Oryza sativa have some aspects of their functions assigned. Therefore, there is an urgent need to develop innovative methods to predict and expand on the currently available functional annotations of plant genes. With open-access catching the 'pulse' of modern day molecular research, an integration of the copious amount of transcriptome datasets allows rapid prediction of gene functions in specific biological contexts, which provide added evidence over traditional homology-based functional inference. The main goal of this dissertation was to develop data analysis strategies and tools broadly applicable in systems biology research.

ISBN: 9780355353648Subjects--Topical Terms:

553671
Bioinformatics.

Transcriptome-based Gene Networks for Systems-level Analysis of Plant Gene Functions.
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