內容註: |
Foreword -- Preface -- 1 Anatomophysiology of the neuroendocrine system: Embryology, Anatomy - Histology - Citology, Physiology -- 2 Epidemiology: Risk factors -- 3 Classification: WHO (grading), site -- 4 Pathology: Anatomic pathology, Immunohistochemistry. - 5 Molecular biology: Molecular pathways, Oncogenes, Suppressor genes -- 6 Clinical presentations: Non functioning NETs -- 7 Clinical presentations: Hormone releasing NETs (Carcinoid syndrome, Insulinoma, Glucagonoma, VIPoma, Somatostatinoma, Others, GRFoma -- 8 MEN 1, MEN 2am, MEN 2b, and Others (TSC, VHL, NF1) -- 9 Diagnosis: (Serum biomarkers, Endoscopy, Imaging (US, CT Scan, MRI, Angiography, Scintigraphy, PET) -- 10 Staging: TNM -- 11 Surgical treatment: Gastric NETs, Duodenum NETs, Jejuno-ileal NETs, Colorectal NETs, Pancreatic NETs (Head, Body-tail), Adrenal NETs -- 12 Non surgical treatments: Chemotherapy, Hormonal syndrome treatment, Targeted therapies, IFN -- 13 Metastatic disease: Liver metastases (Surgery, RF ablation and cryoablation, Arterial chemoembolization) -- 14 Systemic therapy (Somatostatina analogs, Alpha IFN, Cytotoxic chemotherapy, Peptide receptor radiotherapy, VEGF inhibitors, mTOR inhibitors -- 15 Flow-charts. |