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Does Creatine Supplementation Reduce...

Robinson, Nicholas.

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Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?

Record Type:	Electronic resources : Monograph/item
Title/Author:	Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?/
Author:	Robinson, Nicholas.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2017,
Description:	92 p.
Notes:	Source: Masters Abstracts International, Volume: 56-05.
Contained By:	Masters Abstracts International56-05(E).
Subject:	Kinesiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10255141
ISBN:	9780355099478

Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?
Robinson, Nicholas.

Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage? - Ann Arbor : ProQuest Dissertations & Theses, 2017 - 92 p.

Source: Masters Abstracts International, Volume: 56-05.

Thesis (M.Sc.)--University of Toronto (Canada), 2017.

Creatine supplementation (Cr+) is known to increase recovery between exercise bouts and may increase force production capabilities of skeletal muscle. Heat shock proteins (Hsps), are up-regulated in skeletal muscle following damage, particularly following lengthening contractions (LC). Two experiments were conducted to examine the effect of Cr supplementation (Cr+; 14 days 300mg/kg) on skeletal muscle damage following 15 and 25 LCs. In each the left tibilais anterior (TA) of (n=6) Cr+ and Cr- Sprague-Dawley rats underwent LCs (either 15 or 25). No significant differences in TA Hsp content were observed between Cr- and Cr+ animals following 25 LCs, with both showing elevated Hsp72 and 25 content. Fifteen LCs also significantly increased Hsp72 content in both groups, but Hsp25 was significantly elevated only in Cr- animals. In summary, Cr supplementation did not significantly reduce LC induced muscle damage. However, it remains possible that Cr supplementation may reduce stress following 15 LCs.

ISBN: 9780355099478Subjects--Topical Terms:

517627
Kinesiology.

Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?
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245 1 0 $a Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?
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300 $a 92 p.
500 $a Source: Masters Abstracts International, Volume: 56-05.
500 $a Adviser: Marius Locke.
502 $a Thesis (M.Sc.)--University of Toronto (Canada), 2017.
520 $a Creatine supplementation (Cr+) is known to increase recovery between exercise bouts and may increase force production capabilities of skeletal muscle. Heat shock proteins (Hsps), are up-regulated in skeletal muscle following damage, particularly following lengthening contractions (LC). Two experiments were conducted to examine the effect of Cr supplementation (Cr+; 14 days 300mg/kg) on skeletal muscle damage following 15 and 25 LCs. In each the left tibilais anterior (TA) of (n=6) Cr+ and Cr- Sprague-Dawley rats underwent LCs (either 15 or 25). No significant differences in TA Hsp content were observed between Cr- and Cr+ animals following 25 LCs, with both showing elevated Hsp72 and 25 content. Fifteen LCs also significantly increased Hsp72 content in both groups, but Hsp25 was significantly elevated only in Cr- animals. In summary, Cr supplementation did not significantly reduce LC induced muscle damage. However, it remains possible that Cr supplementation may reduce stress following 15 LCs.
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