東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Dual modality optical coherence tomo...

Tate, Tyler Houston.

Linked to FindBook

Google Book

Amazon

博客來

Dual modality optical coherence tomography and multispectral fluorescence imaging for ovarian cancer detection.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Dual modality optical coherence tomography and multispectral fluorescence imaging for ovarian cancer detection./
Author:	Tate, Tyler Houston.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2017,
Description:	202 p.
Notes:	Source: Dissertation Abstracts International, Volume: 78-07(E), Section: B.
Contained By:	Dissertation Abstracts International78-07B(E).
Subject:	Optics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10254209
ISBN:	9781369526974

Dual modality optical coherence tomography and multispectral fluorescence imaging for ovarian cancer detection.
Tate, Tyler Houston.

Dual modality optical coherence tomography and multispectral fluorescence imaging for ovarian cancer detection. - Ann Arbor : ProQuest Dissertations & Theses, 2017 - 202 p.

Source: Dissertation Abstracts International, Volume: 78-07(E), Section: B.

Thesis (Ph.D.)--The University of Arizona, 2017.

This item is not available from ProQuest Dissertations & Theses.

Ovarian cancer is the deadliest gynecologic cancer for women. Diagnosis at the local stage leads to 91% 5-year survival rates, but only 15% of cases are detected early. Existing screening methods have proven ineffective in large clinical trials. Screening is complicated by the heterogeneity of the disease with multiple types of ovarian cancer originating both on the ovary and in the fallopian tube. Early stage cancer is too subtle for non-invasive imaging techniques such as ultrasound or magnetic resonance imaging. This study evaluates the feasibility and design of dual modality, multispectral fluorescence imaging (MFI) and optical coherence tomography (OCT) endoscopes for improved ovarian cancer screening.

ISBN: 9781369526974Subjects--Topical Terms:

517925
Optics.

Dual modality optical coherence tomography and multispectral fluorescence imaging for ovarian cancer detection.
LDR:03063nmm a2200337 4500 001 2125187
005 20171113075201.5
008 180830s2017 ||||||||||||||||| ||eng d
020 $a 9781369526974
035 $a (MiAaPQ)AAI10254209
035 $a AAI10254209
040 $a MiAaPQ $c MiAaPQ
100 1 $a Tate, Tyler Houston. $3 3287238
245 1 0 $a Dual modality optical coherence tomography and multispectral fluorescence imaging for ovarian cancer detection.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2017
300 $a 202 p.
500 $a Source: Dissertation Abstracts International, Volume: 78-07(E), Section: B.
500 $a Adviser: Jennifer Barton.
502 $a Thesis (Ph.D.)--The University of Arizona, 2017.
506 $a This item is not available from ProQuest Dissertations & Theses.
520 $a Ovarian cancer is the deadliest gynecologic cancer for women. Diagnosis at the local stage leads to 91% 5-year survival rates, but only 15% of cases are detected early. Existing screening methods have proven ineffective in large clinical trials. Screening is complicated by the heterogeneity of the disease with multiple types of ovarian cancer originating both on the ovary and in the fallopian tube. Early stage cancer is too subtle for non-invasive imaging techniques such as ultrasound or magnetic resonance imaging. This study evaluates the feasibility and design of dual modality, multispectral fluorescence imaging (MFI) and optical coherence tomography (OCT) endoscopes for improved ovarian cancer screening.
520 $a The study is broken up into three sections. In the first study MFI is validated in an ex vivo imaging study of human ovarian and fallopian tube tissue samples. Tissue autofluorescence excited by ultraviolet and blue wavelengths is shown to be a promising discriminator between normal and cancerous tissue.
520 $a The second study combines OCT and MFI into a sub millimeter diameter endoscope designed to screen for ovarian cancer by screening inside the fallopian tube and at the ovary. The small size is required for screening the full length of the fallopian tube. MFI is implemented as a wide-field navigational imaging technique with high sensitivity complemented by high resolution structural depth imaging of OCT over a limited field of view.
520 $a The final study presents a novel lens design for a scanning fiber endoscope with forward-viewing navigation and side-viewing OCT. A piezo tube is used to scan an optical fiber providing both the navigation channel's illumination and OCT imaging. The design spatially separates the forward-viewing illumination from the OCT. As the piezo fiber circularly scans at its maximum deviation the OCT beam focus is rotationally scanned out the side of the endoscope tip by a rotationally symmetric double reflection in the cover plate.
590 $a School code: 0009.
650 4 $a Optics. $3 517925
650 4 $a Biomedical engineering. $3 535387
690 $a 0752
690 $a 0541
710 2 $a The University of Arizona. $b Optical Sciences. $3 1019548
773 0 $t Dissertation Abstracts International $g 78-07B(E).
790 $a 0009
791 $a Ph.D.
792 $a 2017
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10254209