東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Optimization of PET imaging for simu...

Eldib, Mootaz.

FindBook

Google Book

Amazon

博客來

Optimization of PET imaging for simultaneous PET/MR scanners.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Optimization of PET imaging for simultaneous PET/MR scanners./
作者:	Eldib, Mootaz.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2016,
面頁冊數:	113 p.
附註:	Source: Dissertation Abstracts International, Volume: 78-08(E), Section: B.
Contained By:	Dissertation Abstracts International78-08B(E).
標題:	Biomedical engineering. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10252919
ISBN:	9781369617399

Optimization of PET imaging for simultaneous PET/MR scanners.
Eldib, Mootaz.

Optimization of PET imaging for simultaneous PET/MR scanners. - Ann Arbor : ProQuest Dissertations & Theses, 2016 - 113 p.

Source: Dissertation Abstracts International, Volume: 78-08(E), Section: B.

Thesis (Ph.D.)--The City College of New York, 2016.

Positron emission tomography (PET) imaging is a functional imaging technique with many applications in oncology and cardiovascular imaging. The major advantage of PET is that it is a highly specific and quantitative imaging approach and thus it is often used in staging of disease and in monitoring of therapeutic interventions. In PET, several physical effects must be corrected for ensuring quantitative accuracy. Currently, PET scanners exist as hybrid systems combined with either a computed tomography (CT) or magnetic resonance (MR) scanner for which operation and data acquisition approaches are different. Before the introduction of PET/MRI, PET scans in the clinical were preformed on PET/CT. Because of hardware limitations, PET/CT scanners first acquire CT data followed by the PET scan. The CT part of the scanner provides an anatomical image to merge with the functional PET image and is also is used in various PET data corrections. CT imaging is fast in the order of just a few scans for a whole-body scan, at the expense of exposing the patient to ionizing radiation. In PET/MRI imaging, fully simultaneous acquisition of the anatomical and functional data is possible. MRI exams, take about 30 to 60 minutes, but provide highly resolved anatomical images without radiation exposure. Additionally, MRI is not inherently useful for PET data corrections.

ISBN: 9781369617399Subjects--Topical Terms:

535387
Biomedical engineering.

Optimization of PET imaging for simultaneous PET/MR scanners.
LDR:04239nmm a2200337 4500 001 2122602
005 20170922124930.5
008 180830s2016 ||||||||||||||||| ||eng d
020 $a 9781369617399
035 $a (MiAaPQ)AAI10252919
035 $a AAI10252919
040 $a MiAaPQ $c MiAaPQ
100 1 $a Eldib, Mootaz. $3 3284570
245 1 0 $a Optimization of PET imaging for simultaneous PET/MR scanners.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2016
300 $a 113 p.
500 $a Source: Dissertation Abstracts International, Volume: 78-08(E), Section: B.
500 $a Adviser: Zahi Fayad.
502 $a Thesis (Ph.D.)--The City College of New York, 2016.
520 $a Positron emission tomography (PET) imaging is a functional imaging technique with many applications in oncology and cardiovascular imaging. The major advantage of PET is that it is a highly specific and quantitative imaging approach and thus it is often used in staging of disease and in monitoring of therapeutic interventions. In PET, several physical effects must be corrected for ensuring quantitative accuracy. Currently, PET scanners exist as hybrid systems combined with either a computed tomography (CT) or magnetic resonance (MR) scanner for which operation and data acquisition approaches are different. Before the introduction of PET/MRI, PET scans in the clinical were preformed on PET/CT. Because of hardware limitations, PET/CT scanners first acquire CT data followed by the PET scan. The CT part of the scanner provides an anatomical image to merge with the functional PET image and is also is used in various PET data corrections. CT imaging is fast in the order of just a few scans for a whole-body scan, at the expense of exposing the patient to ionizing radiation. In PET/MRI imaging, fully simultaneous acquisition of the anatomical and functional data is possible. MRI exams, take about 30 to 60 minutes, but provide highly resolved anatomical images without radiation exposure. Additionally, MRI is not inherently useful for PET data corrections.
520 $a The work described in this document focuses on the clinical translation of the newly introduced PET/MRI scanner. Firstly, I worked on attenuation correction methods that could be translated clinically. I also developed acquisition protocols for inflammation imaging in the neck that were specifically tuned for simultaneous PET/MR imaging. Finally, I studied the feasibility of using the PET/MR for Yttrium 90 (Y90) imaging.
520 $a Attenuation correction (AC) for MR imaging surface coils: Photon attenuation is the major physical effect in PET that causes quantitative errors as the patient's body and other imaging hardware around the patient stop the emitted photons before reaching the PET detectors. I utilized the co-acquired MRI data to propose image processing based solutions for AC for various types of MRI surface coils in chapters 2 and 3.
520 $a Low dose protocols PET protocols for PET/MR Imaging: In sequential PET/CT, a PET bed position is acquired for 3-8 minutes and so the radiotracer activity is currently calculated based on this scan time. MR exams are generally about 30-45 minutes, therefore using a simultaneous system both MR and PET data could be collected for the same duration. I will explore the feasibility of matching the duration of the PET scan to that of the MRI to get equivalent PET data (compared to PET/CT), but with much lower levels of the PET radiotracer. This work is discussed in chapter 4.
520 $a Optimization of Yttrium 90 (Y90) PET imaging for simultaneous PET/MR: One possible way for liver cancer treatment is to deliver local, but leather radiation to the tumor using Y90 microspheres. Post delivery PET imaging of the delivered Y90 is useful for dosimetry calculations requiring high quantitative accuracy. The use of PET/MR scanners for such scans might provide additional advantages such as improved motion and attenuation correction, which is discussed in chapter 5.
590 $a School code: 1606.
650 4 $a Biomedical engineering. $3 535387
650 4 $a Medical imaging. $3 3172799
690 $a 0541
690 $a 0574
710 2 $a The City College of New York. $b Biomedical Engineering. $3 3284571
773 0 $t Dissertation Abstracts International $g 78-08B(E).
790 $a 1606
791 $a Ph.D.
792 $a 2016
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10252919