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Photoacoustic lifetime imaging and i...

Shao, Qi.

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Photoacoustic lifetime imaging and its biomedical applications.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Photoacoustic lifetime imaging and its biomedical applications./
Author:	Shao, Qi.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2016,
Description:	102 p.
Notes:	Source: Dissertation Abstracts International, Volume: 77-08(E), Section: B.
Contained By:	Dissertation Abstracts International77-08B(E).
Subject:	Biomedical engineering. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10076317
ISBN:	9781339586182

Photoacoustic lifetime imaging and its biomedical applications.
Shao, Qi.

Photoacoustic lifetime imaging and its biomedical applications. - Ann Arbor : ProQuest Dissertations & Theses, 2016 - 102 p.

Source: Dissertation Abstracts International, Volume: 77-08(E), Section: B.

Thesis (Ph.D.)--University of Minnesota, 2016.

Even though oxygen plays a crucial role in body function and cancer biology, methods of measuring oxygen level in tissue are all limited. The current gold standard relies on an invasive electrode for only single-point reading at a time. The photoacoustic lifetime imaging (PALI) approach overcomes these major limitations by applying photoacoustic probing to oxygen-sensitive optical transient absorption. The capability of assessing oxygen distribution is demonstrated by imaging tumor hypoxia in a small animal model, and monitoring changes of tissue oxygen induced by external modulations. Proposed applications of this imaging technique includes imaging-guided photodynamic therapy (PDT) and activatable probes for molecular imaging.

ISBN: 9781339586182Subjects--Topical Terms:

535387
Biomedical engineering.

Photoacoustic lifetime imaging and its biomedical applications.
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100 1 $a Shao, Qi. $3 3284345
245 1 0 $a Photoacoustic lifetime imaging and its biomedical applications.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2016
300 $a 102 p.
500 $a Source: Dissertation Abstracts International, Volume: 77-08(E), Section: B.
500 $a Adviser: Shai Ashkenazi.
502 $a Thesis (Ph.D.)--University of Minnesota, 2016.
520 $a Even though oxygen plays a crucial role in body function and cancer biology, methods of measuring oxygen level in tissue are all limited. The current gold standard relies on an invasive electrode for only single-point reading at a time. The photoacoustic lifetime imaging (PALI) approach overcomes these major limitations by applying photoacoustic probing to oxygen-sensitive optical transient absorption. The capability of assessing oxygen distribution is demonstrated by imaging tumor hypoxia in a small animal model, and monitoring changes of tissue oxygen induced by external modulations. Proposed applications of this imaging technique includes imaging-guided photodynamic therapy (PDT) and activatable probes for molecular imaging.
590 $a School code: 0130.
650 4 $a Biomedical engineering. $3 535387
650 4 $a Optics. $3 517925
650 4 $a Medical imaging. $3 3172799
690 $a 0541
690 $a 0752
690 $a 0574
710 2 $a University of Minnesota. $b Biomedical Engineering. $3 1669049
773 0 $t Dissertation Abstracts International $g 77-08B(E).
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791 $a Ph.D.
792 $a 2016
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10076317