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Epidemiology and chemotherapy of Ech...
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Ming, Rujing.
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Epidemiology and chemotherapy of Echinococcus granulosus and Echinococcus multilocularis.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Epidemiology and chemotherapy of Echinococcus granulosus and Echinococcus multilocularis./
作者:
Ming, Rujing.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 1993,
面頁冊數:
75 p.
附註:
Source: Dissertation Abstracts International, Volume: 54-03, Section: B, page: 1278.
Contained By:
Dissertation Abstracts International54-03B.
標題:
Zoology. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9316420
Epidemiology and chemotherapy of Echinococcus granulosus and Echinococcus multilocularis.
Ming, Rujing.
Epidemiology and chemotherapy of Echinococcus granulosus and Echinococcus multilocularis.
- Ann Arbor : ProQuest Dissertations & Theses, 1993 - 75 p.
Source: Dissertation Abstracts International, Volume: 54-03, Section: B, page: 1278.
Thesis (Ph.D.)--Brigham Young University, 1993.
Age-prevalence and age-intensity data of Echinococcus granulosus were collected in Xinjiang (northwest China). The frequency distributions of the number of tapeworms per dog and larval cysts per sheep were adequately described by the negative binomial model, suggesting that statistical distributions of parasites are invariably overdispersed. Infection pressure in dogs was determined to be 0.46 infections/year with a mean infection duration of 1.5 years; the infection pressure for sheep was 0.42 infections/year and the mean number of cysts increased linearly by 0.97 cysts/year. The prevalence of the parasite is presumed to be in an endemic state and not regulated by acquired immunity. Regular dog-dosing would readily drive the infection towards extinction.Subjects--Topical Terms:
518878
Zoology.
Epidemiology and chemotherapy of Echinococcus granulosus and Echinococcus multilocularis.
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Epidemiology and chemotherapy of Echinococcus granulosus and Echinococcus multilocularis.
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Source: Dissertation Abstracts International, Volume: 54-03, Section: B, page: 1278.
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Chair: Ferron L. Andersen.
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Thesis (Ph.D.)--Brigham Young University, 1993.
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Age-prevalence and age-intensity data of Echinococcus granulosus were collected in Xinjiang (northwest China). The frequency distributions of the number of tapeworms per dog and larval cysts per sheep were adequately described by the negative binomial model, suggesting that statistical distributions of parasites are invariably overdispersed. Infection pressure in dogs was determined to be 0.46 infections/year with a mean infection duration of 1.5 years; the infection pressure for sheep was 0.42 infections/year and the mean number of cysts increased linearly by 0.97 cysts/year. The prevalence of the parasite is presumed to be in an endemic state and not regulated by acquired immunity. Regular dog-dosing would readily drive the infection towards extinction.
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Mean cysts weights in jirds inoculated with cystic material of Echinococcus multilocularis and treated for 5-day treatment regimes between 29-69 days post-inoculation were higher in praziquantel (PZQ)-treated and lower in mitomycin C (MC)-treated jirds than in controls. Although PZQ treatment enhanced cystic growth, ultrastructural studies showed that PZQ consistently damaged the germinal membrane.
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