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Comprehensive automated analysis of ...

Donaldson, William Hector.

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Comprehensive automated analysis of three-dimensional brain cell-resolution imaging data.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Comprehensive automated analysis of three-dimensional brain cell-resolution imaging data./
Author:	Donaldson, William Hector.
Description:	70 p.
Notes:	Source: Masters Abstracts International, Volume: 55-01.
Contained By:	Masters Abstracts International55-01(E).
Subject:	Biomedical engineering. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1600382
ISBN:	9781339088525

Comprehensive automated analysis of three-dimensional brain cell-resolution imaging data.
Donaldson, William Hector.

Comprehensive automated analysis of three-dimensional brain cell-resolution imaging data. - 70 p.

Source: Masters Abstracts International, Volume: 55-01.

Thesis (Master's)--University of Washington, 2015.

Neuroimaging techniques provide immensely valuable data for medical professionals and academic researchers alike, but analysis of these data is difficult and often relies on subjective interpretations. This project proposes and implements an automated method for comprehensive analysis of brain cell-resolution images acquired through fluorescent microscopy techniques. The image data are prepared using digital signal processing techniques. Next the images are automatically processed in FARSIGHT, an image processing toolkit, to segment, classify, and finally trace microglia. The robustness and viability of this process is shown in its application to several different research projects. This method improves on current analytical techniques with increases in speed, degree of automation, quantifiability, robustness, and repeatability. Automated FARSIGHT-based analysis such as this technique can enable advance research inquiries in the field of neuroscience that were previously inaccessible due to insufficient analytical capabilities.

ISBN: 9781339088525Subjects--Topical Terms:

535387
Biomedical engineering.

Comprehensive automated analysis of three-dimensional brain cell-resolution imaging data.
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020 $a 9781339088525
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100 1 $a Donaldson, William Hector. $3 3191323
245 1 0 $a Comprehensive automated analysis of three-dimensional brain cell-resolution imaging data.
300 $a 70 p.
500 $a Source: Masters Abstracts International, Volume: 55-01.
500 $a Advisers: Eric H. Chudler; William Shain.
502 $a Thesis (Master's)--University of Washington, 2015.
520 $a Neuroimaging techniques provide immensely valuable data for medical professionals and academic researchers alike, but analysis of these data is difficult and often relies on subjective interpretations. This project proposes and implements an automated method for comprehensive analysis of brain cell-resolution images acquired through fluorescent microscopy techniques. The image data are prepared using digital signal processing techniques. Next the images are automatically processed in FARSIGHT, an image processing toolkit, to segment, classify, and finally trace microglia. The robustness and viability of this process is shown in its application to several different research projects. This method improves on current analytical techniques with increases in speed, degree of automation, quantifiability, robustness, and repeatability. Automated FARSIGHT-based analysis such as this technique can enable advance research inquiries in the field of neuroscience that were previously inaccessible due to insufficient analytical capabilities.
590 $a School code: 0250.
650 4 $a Biomedical engineering. $3 535387
650 4 $a Neurosciences. $3 588700
650 4 $a Medical imaging. $3 3172799
690 $a 0541
690 $a 0317
690 $a 0574
710 2 $a University of Washington. $b Bioengineering. $3 2094898
773 0 $t Masters Abstracts International $g 55-01(E).
790 $a 0250
791 $a Master's
792 $a 2015
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1600382