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Data-Driven Motion Detection and Cha...

Shaw, John Dennis.

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Data-Driven Motion Detection and Characterization in PET Brain Scans Using List Mode.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Data-Driven Motion Detection and Characterization in PET Brain Scans Using List Mode./
Author:	Shaw, John Dennis.
Description:	78 p.
Notes:	Source: Masters Abstracts International, Volume: 55-04.
Contained By:	Masters Abstracts International55-04(E).
Subject:	Medical imaging. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10109364
ISBN:	9781339726502

Data-Driven Motion Detection and Characterization in PET Brain Scans Using List Mode.
Shaw, John Dennis.

Data-Driven Motion Detection and Characterization in PET Brain Scans Using List Mode. - 78 p.

Source: Masters Abstracts International, Volume: 55-04.

Thesis (M.S.)--Duke University, 2016.

Head motion during a Positron Emission Tomography (PET) brain scan can considerably degrade image quality. External motion-tracking devices have proven successful in minimizing this effect, but the associated time, maintenance, and workflow changes inhibit their widespread clinical use. List-mode PET acquisition allows for the retroactive analysis of coincidence events on any time scale throughout a scan, and therefore potentially offers a data-driven motion detection and characterization technique. An algorithm was developed to parse list-mode data, divide the full acquisition into short scan intervals, and calculate the line-of-response (LOR) midpoint average for each interval. These LOR midpoint averages, known as "radioactivity centroids," were presumed to represent the center of the radioactivity distribution in the scanner, and it was thought that changes in this metric over time would correspond to intra-scan motion.

ISBN: 9781339726502Subjects--Topical Terms:

3172799
Medical imaging.

Data-Driven Motion Detection and Characterization in PET Brain Scans Using List Mode.
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245 1 0 $a Data-Driven Motion Detection and Characterization in PET Brain Scans Using List Mode.
300 $a 78 p.
500 $a Source: Masters Abstracts International, Volume: 55-04.
500 $a Adviser: Timothy G. Turkington.
502 $a Thesis (M.S.)--Duke University, 2016.
520 $a Head motion during a Positron Emission Tomography (PET) brain scan can considerably degrade image quality. External motion-tracking devices have proven successful in minimizing this effect, but the associated time, maintenance, and workflow changes inhibit their widespread clinical use. List-mode PET acquisition allows for the retroactive analysis of coincidence events on any time scale throughout a scan, and therefore potentially offers a data-driven motion detection and characterization technique. An algorithm was developed to parse list-mode data, divide the full acquisition into short scan intervals, and calculate the line-of-response (LOR) midpoint average for each interval. These LOR midpoint averages, known as "radioactivity centroids," were presumed to represent the center of the radioactivity distribution in the scanner, and it was thought that changes in this metric over time would correspond to intra-scan motion.
520 $a Several scans were taken of the 3D Hoffman brain phantom on a GE Discovery IQ PET/CT scanner to test the ability of the radioactivity to indicate intra-scan motion. Each scan incrementally surveyed motion in a different degree of freedom (2 translational and 2 rotational). The radioactivity centroids calculated from these scans correlated linearly to phantom positions/orientations. Centroid measurements over 1-second intervals performed on scans with ~1mCi of activity in the center of the field of view had standard deviations of 0.026 cm in the x- and y-dimensions and 0.020 cm in the z-dimension, which demonstrates high precision and repeatability in this metric. Radioactivity centroids are thus shown to successfully represent discrete motions on the submillimeter scale. It is also shown that while the radioactivity centroid can precisely indicate the amount of motion during an acquisition, it fails to distinguish what type of motion occurred.
590 $a School code: 0066.
650 4 $a Medical imaging. $3 3172799
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710 2 $a Duke University. $b Medical Physics. $3 2101548
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