東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Novel Approaches in Assessing Abuse ...

Zhang, Yang Maria.

FindBook

Google Book

Amazon

博客來

Novel Approaches in Assessing Abuse Potential of Psychotropic Medications - Pregabalin as a Test Case.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Novel Approaches in Assessing Abuse Potential of Psychotropic Medications - Pregabalin as a Test Case./
作者:	Zhang, Yang Maria.
面頁冊數:	149 p.
附註:	Source: Masters Abstracts International, Volume: 55-04.
Contained By:	Masters Abstracts International55-04(E).
標題:	Pharmaceutical sciences. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10044015
ISBN:	9781339554686

Novel Approaches in Assessing Abuse Potential of Psychotropic Medications - Pregabalin as a Test Case.
Zhang, Yang Maria.

Novel Approaches in Assessing Abuse Potential of Psychotropic Medications - Pregabalin as a Test Case. - 149 p.

Source: Masters Abstracts International, Volume: 55-04.

Thesis (M.Sc.)--University of Toronto (Canada), 2016.

Abuse of psychotropic medications causes significant morbidity and mortality in North America. Results from traditional assessments of abuse liability may not be generalizable to individuals with mental illnesses or for drugs with ill-defined mechanisms of action. Pregabalin is an anticonvulsant medication used off-label to manage benzodiazepine withdrawal symptoms. Simultaneously, reports of its abuse have emerged. Two novel approaches were used to assess pregabalin's abuse potential. On the macro-level, adverse drug reaction data from Canada's national database were evaluated in Study 1. Results indicated that cases found in this spontaneous reporting system can provide early indicators of prescription drug abuse. On the micro-level, Study 2 aimed to assess the acute effects of pregabalin in inpatients withdrawing from benzodiazepines and produced valuable information concerning study design, which can be used to inform future research. Overall, these novel macro-and micro-level approaches in assessing abuse potential of psychotropic drugs are complementary and synergistic with traditional methods.

ISBN: 9781339554686Subjects--Topical Terms:

3173021
Pharmaceutical sciences.

Novel Approaches in Assessing Abuse Potential of Psychotropic Medications - Pregabalin as a Test Case.
LDR:02000nmm a2200277 4500 001 2075192
005 20161024150917.5
008 170521s2016 ||||||||||||||||| ||eng d
020 $a 9781339554686
035 $a (MiAaPQ)AAI10044015
035 $a AAI10044015
040 $a MiAaPQ $c MiAaPQ
100 1 $a Zhang, Yang Maria. $3 3190569
245 1 0 $a Novel Approaches in Assessing Abuse Potential of Psychotropic Medications - Pregabalin as a Test Case.
300 $a 149 p.
500 $a Source: Masters Abstracts International, Volume: 55-04.
500 $a Adviser: Beth A. Sproule.
502 $a Thesis (M.Sc.)--University of Toronto (Canada), 2016.
520 $a Abuse of psychotropic medications causes significant morbidity and mortality in North America. Results from traditional assessments of abuse liability may not be generalizable to individuals with mental illnesses or for drugs with ill-defined mechanisms of action. Pregabalin is an anticonvulsant medication used off-label to manage benzodiazepine withdrawal symptoms. Simultaneously, reports of its abuse have emerged. Two novel approaches were used to assess pregabalin's abuse potential. On the macro-level, adverse drug reaction data from Canada's national database were evaluated in Study 1. Results indicated that cases found in this spontaneous reporting system can provide early indicators of prescription drug abuse. On the micro-level, Study 2 aimed to assess the acute effects of pregabalin in inpatients withdrawing from benzodiazepines and produced valuable information concerning study design, which can be used to inform future research. Overall, these novel macro-and micro-level approaches in assessing abuse potential of psychotropic drugs are complementary and synergistic with traditional methods.
590 $a School code: 0779.
650 4 $a Pharmaceutical sciences. $3 3173021
650 4 $a Mental health. $3 534751
690 $a 0572
690 $a 0347
710 2 $a University of Toronto (Canada). $b Pharmaceutical Sciences. $3 3170825
773 0 $t Masters Abstracts International $g 55-04(E).
790 $a 0779
791 $a M.Sc.
792 $a 2016
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10044015