東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Spatial genetic characterizations of...

Nguyen-Phuc, Hoa.

Linked to FindBook

Google Book

Amazon

博客來

Spatial genetic characterizations of neutral and adaptive variation of Red Junglefowl (Gallus gallus) in South Central Vietnam.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Spatial genetic characterizations of neutral and adaptive variation of Red Junglefowl (Gallus gallus) in South Central Vietnam./
Author:	Nguyen-Phuc, Hoa.
Description:	161 p.
Notes:	Source: Dissertation Abstracts International, Volume: 76-12(E), Section: B.
Contained By:	Dissertation Abstracts International76-12B(E).
Subject:	Animal sciences. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3719223
ISBN:	9781321995145

Spatial genetic characterizations of neutral and adaptive variation of Red Junglefowl (Gallus gallus) in South Central Vietnam.
Nguyen-Phuc, Hoa.

Spatial genetic characterizations of neutral and adaptive variation of Red Junglefowl (Gallus gallus) in South Central Vietnam. - 161 p.

Source: Dissertation Abstracts International, Volume: 76-12(E), Section: B.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2015.

Genetic diversity is inherently a spatial process of stochastic and directional evolutionary forces, as well as the interactions between such forces with the underlying environment. These factors may operate simultaneously and are challenging to understand, particularly in highly-mobile species or species who are dependent to human activities. In this dissertation, I employed molecular technologies and spatial analyses to examine genetic diversity in Red Junglefowl (Gallus gallus), an important agricultural species. My aim was to understand how spatial processes affect genetic diversity and how landscape patterns may influence population structure at microgeographic scales. I screened 212 wild Red Junglefowl sampled across diverse habitats in South Central Vietnam with two genomic tools. First, analyses of 289 amplified fragment length polymorphisms (AFLPs) identified high degree of interspecific-population differentiation (overall FST = 0.1028) with no evidence of contemporary long-distance genetic exchanges especially across the major barrier Annamite Mountain Range. Fine-scale spatial landscape models detected substantial intraspecific genetic subdivision to distances as low as 5 km. The magnitude of spatial neutral variation of the ground-dwelling pheasants, however, showed no causative relationship between landscape features of landcover and topography. Second, I interrogated an 84-SNP panel sites spanning the entire 242 Kb major histocompatibility complex (MHC) B-locus and identified 310 unique MHC haplotypes (77.89% of the total 398 chromosomes). Comparison to 17 lines of domestic chickens indicated that wild Red Junglefowl have extraordinarily high haplotypic diversity. The majority of variation in MHC haplotypes (94.51%) occurred within individuals while genetic differentiation between populations was negligible (overall FST = 0.0083). Likely augmented by recombination, the B-locus also exhibited a few areas of strong linkage suggesting perhaps concerted evolution against a common pathogen. Overall, the results suggest the spatial pattern of MHC is adaptive and under the influence of balancing selection while neutral AFLPs reflect demographic processes and movements of the birds. I conclude that wild populations of Red Junglefowl in Vietnam represent one of the richest resources of natural genomic variation. Both neutral and adaptive genetic diversity should be equally considered in a spatial research framework for future management of animal genetic diversity, including application to agricultural stock improvement.

ISBN: 9781321995145Subjects--Topical Terms:

3174829
Animal sciences.

Spatial genetic characterizations of neutral and adaptive variation of Red Junglefowl (Gallus gallus) in South Central Vietnam.
LDR:03541nmm a2200289 4500 001 2074453
005 20161004114935.5
008 170521s2015 ||||||||||||||||| ||eng d
020 $a 9781321995145
035 $a (MiAaPQ)AAI3719223
035 $a AAI3719223
040 $a MiAaPQ $c MiAaPQ
100 1 $a Nguyen-Phuc, Hoa. $3 3189772
245 1 0 $a Spatial genetic characterizations of neutral and adaptive variation of Red Junglefowl (Gallus gallus) in South Central Vietnam.
300 $a 161 p.
500 $a Source: Dissertation Abstracts International, Volume: 76-12(E), Section: B.
500 $a Adviser: Mark E. Berres.
502 $a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2015.
520 $a Genetic diversity is inherently a spatial process of stochastic and directional evolutionary forces, as well as the interactions between such forces with the underlying environment. These factors may operate simultaneously and are challenging to understand, particularly in highly-mobile species or species who are dependent to human activities. In this dissertation, I employed molecular technologies and spatial analyses to examine genetic diversity in Red Junglefowl (Gallus gallus), an important agricultural species. My aim was to understand how spatial processes affect genetic diversity and how landscape patterns may influence population structure at microgeographic scales. I screened 212 wild Red Junglefowl sampled across diverse habitats in South Central Vietnam with two genomic tools. First, analyses of 289 amplified fragment length polymorphisms (AFLPs) identified high degree of interspecific-population differentiation (overall FST = 0.1028) with no evidence of contemporary long-distance genetic exchanges especially across the major barrier Annamite Mountain Range. Fine-scale spatial landscape models detected substantial intraspecific genetic subdivision to distances as low as 5 km. The magnitude of spatial neutral variation of the ground-dwelling pheasants, however, showed no causative relationship between landscape features of landcover and topography. Second, I interrogated an 84-SNP panel sites spanning the entire 242 Kb major histocompatibility complex (MHC) B-locus and identified 310 unique MHC haplotypes (77.89% of the total 398 chromosomes). Comparison to 17 lines of domestic chickens indicated that wild Red Junglefowl have extraordinarily high haplotypic diversity. The majority of variation in MHC haplotypes (94.51%) occurred within individuals while genetic differentiation between populations was negligible (overall FST = 0.0083). Likely augmented by recombination, the B-locus also exhibited a few areas of strong linkage suggesting perhaps concerted evolution against a common pathogen. Overall, the results suggest the spatial pattern of MHC is adaptive and under the influence of balancing selection while neutral AFLPs reflect demographic processes and movements of the birds. I conclude that wild populations of Red Junglefowl in Vietnam represent one of the richest resources of natural genomic variation. Both neutral and adaptive genetic diversity should be equally considered in a spatial research framework for future management of animal genetic diversity, including application to agricultural stock improvement.
590 $a School code: 0262.
650 4 $a Animal sciences. $3 3174829
650 4 $a Ecology. $3 516476
650 4 $a Natural resource management. $3 589570
690 $a 0475
690 $a 0329
690 $a 0528
710 2 $a The University of Wisconsin - Madison. $b Animal Sciences. $3 2096734
773 0 $t Dissertation Abstracts International $g 76-12B(E).
790 $a 0262
791 $a Ph.D.
792 $a 2015
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3719223