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Predicting Droplet Formation on Cent...
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Moebius, Jacob Alfred.
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Predicting Droplet Formation on Centrifugal Microfluidic Platforms.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Predicting Droplet Formation on Centrifugal Microfluidic Platforms./
作者:
Moebius, Jacob Alfred.
面頁冊數:
57 p.
附註:
Source: Masters Abstracts International, Volume: 54-04.
Contained By:
Masters Abstracts International54-04(E).
標題:
Biomedical engineering. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1585691
ISBN:
9781321646306
Predicting Droplet Formation on Centrifugal Microfluidic Platforms.
Moebius, Jacob Alfred.
Predicting Droplet Formation on Centrifugal Microfluidic Platforms.
- 57 p.
Source: Masters Abstracts International, Volume: 54-04.
Thesis (M.S.)--University of California, Irvine, 2015.
Centrifugal microfluidics is a widely known research tool for biological sample and water quality analysis. Currently, the standard equipment used for such diagnostic applications include slow, bulky machines controlled by multiple operators. These machines can be condensed into a smaller, faster benchtop sample-to-answer system.
ISBN: 9781321646306Subjects--Topical Terms:
535387
Biomedical engineering.
Predicting Droplet Formation on Centrifugal Microfluidic Platforms.
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Adviser: Marc J. Madou.
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Thesis (M.S.)--University of California, Irvine, 2015.
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Centrifugal microfluidics is a widely known research tool for biological sample and water quality analysis. Currently, the standard equipment used for such diagnostic applications include slow, bulky machines controlled by multiple operators. These machines can be condensed into a smaller, faster benchtop sample-to-answer system.
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Sample processing is an important step taken to extract, isolate, and convert biological factors, such as nucleic acids or proteins, from a raw sample to an analyzable solution. Volume definition is one such step. The focus of this thesis is the development of a model predicting monodispersed droplet formation and the application of droplets as a technique for volume definition.
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First, a background of droplet microfluidic platforms is presented, along with current biological analysis technologies and the advantages of integrating such technologies onto microfluidic platforms. Second, background and theories of centrifugal microfluidics is given, followed by theories relevant to droplet emulsions. Third, fabrication techniques for centrifugal microfluidic designs are discussed. Finally, the development of a model for predicting droplet formation on the centrifugal microfluidic platform are presented for the rest of the thesis.
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Predicting droplet formation analytically based on the volumetric flow rates of the continuous and dispersed phases, the ratios of these two flow rates, and the interfacial tension between the continuous and dispersed phases presented many challenges, which will be discussed in this work. Experimental validation was completed using continuous phase solutions of different interfacial tensions. To conclude, prospective applications are discussed with expected challenges.
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