東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Synthesis and supramolecular assembl...

Marciel, Amanda Brittany.

Linked to FindBook

Google Book

Amazon

博客來

Synthesis and supramolecular assembly of biomimetic polymers.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Synthesis and supramolecular assembly of biomimetic polymers./
Author:	Marciel, Amanda Brittany.
Description:	151 p.
Notes:	Source: Dissertation Abstracts International, Volume: 77-05(E), Section: B.
Contained By:	Dissertation Abstracts International77-05B(E).
Subject:	Chemical engineering. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3740504
ISBN:	9781339326214

Synthesis and supramolecular assembly of biomimetic polymers.
Marciel, Amanda Brittany.

Synthesis and supramolecular assembly of biomimetic polymers. - 151 p.

Source: Dissertation Abstracts International, Volume: 77-05(E), Section: B.

Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2015.

A grand challenge in materials chemistry is the synthesis of macromolecules and polymers with precise shapes and architectures. Polymer microstructure and architecture strongly affect the resulting functionality of advanced materials, yet understanding the static and dynamic properties of these complex macromolecules in bulk has been difficult due to their inherit polydispersity. Single molecule studies have provided a wealth of information on linear flexible and semi-flexible polymers in dilute solutions. However, few investigations have focused on industrially relevant complex topologies (e.g., star, comb, hyperbranched polymers) in industrially relevant solution conditions (e.g., semi-dilute, concentrated). Therefore, from this perspective there is a strong need to synthesize precision complex architectures for bulk studies as well as complex architectures compatible with current single molecule techniques to study static and dynamic polymer properties.

ISBN: 9781339326214Subjects--Topical Terms:

560457
Chemical engineering.

Synthesis and supramolecular assembly of biomimetic polymers.
LDR:03357nmm a2200313 4500 001 2067531
005 20160411144745.5
008 170521s2015 ||||||||||||||||| ||eng d
020 $a 9781339326214
035 $a (MiAaPQ)AAI3740504
035 $a AAI3740504
040 $a MiAaPQ $c MiAaPQ
100 1 $a Marciel, Amanda Brittany. $3 3182384
245 1 0 $a Synthesis and supramolecular assembly of biomimetic polymers.
300 $a 151 p.
500 $a Source: Dissertation Abstracts International, Volume: 77-05(E), Section: B.
500 $a Adviser: Charles M. Schroeder.
502 $a Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2015.
520 $a A grand challenge in materials chemistry is the synthesis of macromolecules and polymers with precise shapes and architectures. Polymer microstructure and architecture strongly affect the resulting functionality of advanced materials, yet understanding the static and dynamic properties of these complex macromolecules in bulk has been difficult due to their inherit polydispersity. Single molecule studies have provided a wealth of information on linear flexible and semi-flexible polymers in dilute solutions. However, few investigations have focused on industrially relevant complex topologies (e.g., star, comb, hyperbranched polymers) in industrially relevant solution conditions (e.g., semi-dilute, concentrated). Therefore, from this perspective there is a strong need to synthesize precision complex architectures for bulk studies as well as complex architectures compatible with current single molecule techniques to study static and dynamic polymer properties.
520 $a In this way, we developed a hybrid synthetic strategy to produce branched polymer architectures based on chemically modified DNA. Overall, this approach enables control of backbone length and flexibility, as well as branch grafting density and chemical identity. We utilized a two-step scheme based on enzymatic incorporation of non-natural nucleotides containing bioorthogonal dibenzocyclooctyne (DBCO) functional groups along the main polymer backbone, followed by copper-free "click" chemistry to graft synthetic polymer branches or oligonucleotide branches to the DNA backbone, thereby allowing for the synthesis of a variety of polymer architectures, including three-arm stars, H-polymers, graft block copolymers, and comb polymers for materials assembly and single molecule studies.
520 $a Bulk materials properties are also affected by industrial processing conditions that alter polymer morphology. Therefore, in an alternative strategy we developed a microfluidic-based approach to assemble highly aligned synthetic oligopeptides nanostructures using microscale extensional flows. This strategy enabled reproducible, reliable fabrication of aligned hierarchical constructs that do not form spontaneously in solution. In this way, fluidic-directed assembly of supramolecular structures allows for unprecedented manipulation at the nano- and mesoscale, which has the potential to provide rapid and efficient control of functional materials properties.
590 $a School code: 0090.
650 4 $a Chemical engineering. $3 560457
650 4 $a Materials science. $3 543314
650 4 $a Polymer chemistry. $3 3173488
690 $a 0542
690 $a 0794
690 $a 0495
710 2 $a University of Illinois at Urbana-Champaign. $b School of Molecular and Cell Biology. $3 3182385
773 0 $t Dissertation Abstracts International $g 77-05B(E).
790 $a 0090
791 $a Ph.D.
792 $a 2015
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3740504