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The relation of antioxidant nutrient...

Hu, Guizhou.

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The relation of antioxidant nutrients to lung function and chronic obstructive pulmonary disease.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The relation of antioxidant nutrients to lung function and chronic obstructive pulmonary disease./
作者:	Hu, Guizhou.
面頁冊數:	103 p.
附註:	Source: Dissertation Abstracts International, Volume: 59-06, Section: B, page: 2499.
Contained By:	Dissertation Abstracts International59-06B.
標題:	Animal sciences. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9837890
ISBN:	9780591915389

The relation of antioxidant nutrients to lung function and chronic obstructive pulmonary disease.
Hu, Guizhou.

The relation of antioxidant nutrients to lung function and chronic obstructive pulmonary disease. - 103 p.

Source: Dissertation Abstracts International, Volume: 59-06, Section: B, page: 2499.

Thesis (Ph.D.)--Cornell University, 1998.

A growing understanding of the patho-physiology of the chronic obstructive pulmonary disease (COPD) has raised interest in the relation of nutrition to COPD. The present study investigated the associations of the major antioxidant nutrients, namely, vitamins C and E, $\beta$-carotene and selenium, with lung function and COPD by analysis of data from a study of diet, life style and mortality in China and data from the Third National Health and Nutrition Examination Survey (NHANES III) conducted in the U.S.

ISBN: 9780591915389Subjects--Topical Terms:

3174829
Animal sciences.

The relation of antioxidant nutrients to lung function and chronic obstructive pulmonary disease.
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100 1 $a Hu, Guizhou. $3 3182002
245 1 4 $a The relation of antioxidant nutrients to lung function and chronic obstructive pulmonary disease.
300 $a 103 p.
500 $a Source: Dissertation Abstracts International, Volume: 59-06, Section: B, page: 2499.
500 $a Adviser: T. C. Campbell.
502 $a Thesis (Ph.D.)--Cornell University, 1998.
520 $a A growing understanding of the patho-physiology of the chronic obstructive pulmonary disease (COPD) has raised interest in the relation of nutrition to COPD. The present study investigated the associations of the major antioxidant nutrients, namely, vitamins C and E, $\beta$-carotene and selenium, with lung function and COPD by analysis of data from a study of diet, life style and mortality in China and data from the Third National Health and Nutrition Examination Survey (NHANES III) conducted in the U.S.
520 $a The study in China was conducted in 69 rural counties in 1989, and 120 subjects were selected from each county. An ecological analysis showed that the county-specific plasma vitamins C and E and selenium were protectively associated with county mean lung function and COPD mortality after adjusting for other covariates. A cross-sectional analysis of individuals showed that the dietary intake of vitamin C was significantly and positively related to lung function (forced expiratory volume in the first second (FEV$\sb1$)) in a multiple regression analysis after adjusting for sex, age, height, weight, caloric intake, smoking and education. Finally, in a case-control study of COPD risk, increasing plasma $\beta$-carotene was found to be associated with a decreased risk of disease, although the relation was not statistically significant.
520 $a The NHANES III data comprised a sample representative of the U.S. population in 1988-94 (N = 18, 162, age $\ge$ 17 yrs). In a multiple regression analysis, after adjusting for sex, age, height, body mass index, race, income and cigarette smoking, FEV$\sb1$ was significantly associated with each of the dietary and serum antioxidant nutrients examined. When all of the antioxidant nutrients were considered simultaneously (diet and serum variables were still considered in separate models), an independent association was observed for each antioxidant nutrient. The association of particular antioxidants with FEV$\sb1$ varied according to smoking status, such that the serum $\beta$-carotene was less protectively associated with FEV$\sb1$ among current smokers than nonsmokers, while the serum selenium had a more protective effect among smokers.
520 $a The present study provides strong evidence that antioxidant nutrients may protect lung function and decrease the risk of developing COPD.
590 $a School code: 0058.
650 4 $a Animal sciences. $3 3174829
650 4 $a Animal Physiology. $3 894174
690 $a 0475
690 $a 0433
710 2 $a Cornell University. $3 530586
773 0 $t Dissertation Abstracts International $g 59-06B.
790 $a 0058
791 $a Ph.D.
792 $a 1998
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9837890