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The Gastrointestinal Microbiome and ...
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Herbert, Kyle M.
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The Gastrointestinal Microbiome and Diet-Induced Dysbiosis: Influence on Obesity and Chronic Disease Risk.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
The Gastrointestinal Microbiome and Diet-Induced Dysbiosis: Influence on Obesity and Chronic Disease Risk./
作者:
Herbert, Kyle M.
面頁冊數:
45 p.
附註:
Source: Masters Abstracts International, Volume: 54-05.
Contained By:
Masters Abstracts International54-05(E).
標題:
Immunology. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1589314
ISBN:
9781321766882
The Gastrointestinal Microbiome and Diet-Induced Dysbiosis: Influence on Obesity and Chronic Disease Risk.
Herbert, Kyle M.
The Gastrointestinal Microbiome and Diet-Induced Dysbiosis: Influence on Obesity and Chronic Disease Risk.
- 45 p.
Source: Masters Abstracts International, Volume: 54-05.
Thesis (M.S.)--University of South Carolina, 2015.
This review will explore various aspects of the gastrointestinal microbiome and examine the recent scientific literature on the underlying mechanisms surrounding high-fat-diet (HFD)-induced alterations in gut microbiota and the subsequent development of obesity. Excessive consumption of HFDs has undoubtedly contributed to the obesity epidemic. However, the mechanisms responsible for this relationship are likely to be more complex than the simple concept of energy balance. Emerging literature has implicated HFD-induced alterations in gut microbiota in the obesity epidemic, from both an immunological and metabolic standpoint. These alterations have been associated with obesity and subsequent development of inflammatory-mediated chronic diseases such as irritable bowel disease, colorectal cancer, and certain autoimmune disorders. Potential mechanisms for this effect include: 1) changes in energy regulation and an improved capacity for energy harvest, 2) an increase in lipoprotein lipase (LPL) activity, and 3) enhanced gut permeability perpetuating metabolic endotoxemia and subsequent inflammation. This review will highlight the most important recent advances linking the gut microbiota, HFD-induced dysbiosis, and obesity, as well as explore potential mechanisms for this effect and the implications for chronic disease development. A better understanding of the mechanisms linking HFD to alterations in gut microbiota is necessary to allow for the regulation of dysbiosis and subsequent promotion of anti-obesity effects.
ISBN: 9781321766882Subjects--Topical Terms:
611031
Immunology.
The Gastrointestinal Microbiome and Diet-Induced Dysbiosis: Influence on Obesity and Chronic Disease Risk.
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