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Theoretical and experimental neutron...

Perez-Andujar, Angelica A.

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Theoretical and experimental neutron dose determination for proton therapy delivery techniques.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Theoretical and experimental neutron dose determination for proton therapy delivery techniques./
Author:	Perez-Andujar, Angelica A.
Description:	118 p.
Notes:	Source: Dissertation Abstracts International, Volume: 70-11, Section: B, page: 6966.
Contained By:	Dissertation Abstracts International70-11B.
Subject:	Nuclear physics and radiation. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3384447
ISBN:	9781109476996

Theoretical and experimental neutron dose determination for proton therapy delivery techniques.
Perez-Andujar, Angelica A.

Theoretical and experimental neutron dose determination for proton therapy delivery techniques. - 118 p.

Source: Dissertation Abstracts International, Volume: 70-11, Section: B, page: 6966.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2009.

In recent years the use of high energy protons in radiotherapy has increased dramatically. The clinical advantages are apparent, but there is some controversy regarding the secondary neutrons produced during treatment. This work presents a study of neutron production in proton therapy. We examined the neutron production due to materials typically present in a treatment nozzle. In addition, the neutron field characteristics, fluence, energy spectra and absorbed dose were investigated for a contemporary passive system. Microdosimetric measurements were performed to quantify the neutron field characteristics for a passive beam delivery system.

ISBN: 9781109476996Subjects--Topical Terms:

3173793
Nuclear physics and radiation.

Theoretical and experimental neutron dose determination for proton therapy delivery techniques.
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020 $a 9781109476996
035 $a (MiAaPQ)AAI3384447
035 $a AAI3384447
040 $a MiAaPQ $c MiAaPQ
100 1 $a Perez-Andujar, Angelica A. $3 3178598
245 1 0 $a Theoretical and experimental neutron dose determination for proton therapy delivery techniques.
300 $a 118 p.
500 $a Source: Dissertation Abstracts International, Volume: 70-11, Section: B, page: 6966.
500 $a Adviser: Paul M. DeLuca, Jr.
502 $a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2009.
520 $a In recent years the use of high energy protons in radiotherapy has increased dramatically. The clinical advantages are apparent, but there is some controversy regarding the secondary neutrons produced during treatment. This work presents a study of neutron production in proton therapy. We examined the neutron production due to materials typically present in a treatment nozzle. In addition, the neutron field characteristics, fluence, energy spectra and absorbed dose were investigated for a contemporary passive system. Microdosimetric measurements were performed to quantify the neutron field characteristics for a passive beam delivery system.
520 $a The neutron absorbed dose is dependent on the type of material with which the primary proton beam interacts. Lower atomic number materials produce fewer neutrons, although they are forward directed and have energies close to the primary proton beam. Higher atomic number materials produce a larger number of evaporation neutrons emitted nearly isotropically, although there is some forward directed production. This behavior was confirmed by microdosimetric measurements for thick targets. In addition, from our studies and measurements, we determined that the treatment snout is in fact the maximum neutron dose contributor to the dose that a patient will receive during proton therapy. Other beam shaping devices, such as the range modulation wheel (RMW), produce a greater neutron fluence within the nozzle but do not dominate the neutron dose receive by the patient.
590 $a School code: 0262.
650 4 $a Nuclear physics and radiation. $3 3173793
650 4 $a Biophysics. $3 518360
690 $a 0756
690 $a 0760
710 2 $a The University of Wisconsin - Madison. $3 626640
773 0 $t Dissertation Abstracts International $g 70-11B.
790 $a 0262
791 $a Ph.D.
792 $a 2009
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3384447