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The etiology of thumb carpometacarpa...
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Zheng, Qi.
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The etiology of thumb carpometacarpal osteoarthritis: Early indications from in vivo joint contact mechanics.
Record Type:
Electronic resources : Monograph/item
Title/Author:
The etiology of thumb carpometacarpal osteoarthritis: Early indications from in vivo joint contact mechanics./
Author:
Zheng, Qi.
Description:
104 p.
Notes:
Source: Masters Abstracts International, Volume: 53-02.
Contained By:
Masters Abstracts International53-02(E).
Subject:
Biomechanics. -
Online resource:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1559000
ISBN:
9781303996979
The etiology of thumb carpometacarpal osteoarthritis: Early indications from in vivo joint contact mechanics.
Zheng, Qi.
The etiology of thumb carpometacarpal osteoarthritis: Early indications from in vivo joint contact mechanics.
- 104 p.
Source: Masters Abstracts International, Volume: 53-02.
Thesis (M.S.)--University of Kansas, 2014.
This item must not be sold to any third party vendors.
The thumb carpometacarpal (CMC) joint is frequently affected by osteoarthritis (OA). The prevalence of thumb CMC OA greatly increases with age and has disproportional predominance in postmenopausal women. However, so far the etiology of thumb CMC OA remains unclear, and no conclusion has been achieved regarding the selection of the optimal surgical procedure. Joint contact mechanics can be an important aspect in understanding the mechanism of thumb CMC OA development. The contact pressure distribution on the articular surface directly affects the cartilage condition. This study quantitatively compared the in vivo thumb CMC joint contact mechanics between 4 males and 4 females using finite element modeling (FEM), and also evaluated the accuracy of a time-efficient surface-based contact modeling (SCM) procedure for possible clinical application. Although a sufficient statistical power cannot be achieved with the small number of subjects, the contact patterns were substantially different between male and female groups. Contact area, force and peak contact pressure showed a trend of increase in the older female subjects. Compared with FEM, the contact parameter values from SCM may be somewhat less accurate, but SCM produced contact distribution patterns similar to FEM. In addition, SCM was able to distinguish the different contact patterns between normal and osteoarthritic thumb CMC joints with much less data processing. Therefore, SCM has clear potential for future clinical diagnosis and the evaluation of treatment efficacy for thumb CMC OA.
ISBN: 9781303996979Subjects--Topical Terms:
548685
Biomechanics.
The etiology of thumb carpometacarpal osteoarthritis: Early indications from in vivo joint contact mechanics.
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104 p.
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Source: Masters Abstracts International, Volume: 53-02.
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Adviser: Kenneth J. Fischer.
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Thesis (M.S.)--University of Kansas, 2014.
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The thumb carpometacarpal (CMC) joint is frequently affected by osteoarthritis (OA). The prevalence of thumb CMC OA greatly increases with age and has disproportional predominance in postmenopausal women. However, so far the etiology of thumb CMC OA remains unclear, and no conclusion has been achieved regarding the selection of the optimal surgical procedure. Joint contact mechanics can be an important aspect in understanding the mechanism of thumb CMC OA development. The contact pressure distribution on the articular surface directly affects the cartilage condition. This study quantitatively compared the in vivo thumb CMC joint contact mechanics between 4 males and 4 females using finite element modeling (FEM), and also evaluated the accuracy of a time-efficient surface-based contact modeling (SCM) procedure for possible clinical application. Although a sufficient statistical power cannot be achieved with the small number of subjects, the contact patterns were substantially different between male and female groups. Contact area, force and peak contact pressure showed a trend of increase in the older female subjects. Compared with FEM, the contact parameter values from SCM may be somewhat less accurate, but SCM produced contact distribution patterns similar to FEM. In addition, SCM was able to distinguish the different contact patterns between normal and osteoarthritic thumb CMC joints with much less data processing. Therefore, SCM has clear potential for future clinical diagnosis and the evaluation of treatment efficacy for thumb CMC OA.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1559000
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