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Attitudes toward Whole Genome Sequen...

Rashkin, Misha Dmitry Shepard.

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Attitudes toward Whole Genome Sequencing among Parents of Children with Autism Spectrum Disorder: A Qualitative Interview Study.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Attitudes toward Whole Genome Sequencing among Parents of Children with Autism Spectrum Disorder: A Qualitative Interview Study./
作者:	Rashkin, Misha Dmitry Shepard.
面頁冊數:	54 p.
附註:	Source: Masters Abstracts International, Volume: 51-06.
Contained By:	Masters Abstracts International51-06(E).
標題:	Biology, Genetics. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1537181
ISBN:	9781303073489

Attitudes toward Whole Genome Sequencing among Parents of Children with Autism Spectrum Disorder: A Qualitative Interview Study.
Rashkin, Misha Dmitry Shepard.

Attitudes toward Whole Genome Sequencing among Parents of Children with Autism Spectrum Disorder: A Qualitative Interview Study. - 54 p.

Source: Masters Abstracts International, Volume: 51-06.

Thesis (M.S.)--Icahn School of Medicine at Mount Sinai, 2013.

Background: Whole genome sequencing (WGS) is increasingly used for research and clinical purposes. This study explored attitudes of parents of children with a suspected autism spectrum disorder (ASD) toward WGS. Methods: A topic guide informed by the Theory of Planned Behavior was developed covering perceived benefits, concerns, barriers, and facilitators regarding WGS. Participants also summarized likely major factors in their decision. Interviews were audio-recorded, transcribed and analyzed for themes using framework analysis. Results: Participants (n=10) were generally in favor of WGS. The most recurring themes were: helping their affected child; concerns that secondary findings could be emotionally overwhelming; facilitators relating to access, e.g. living near a major medical center. When summarizing, money/insurance issues were most raised; this was also the most recurring barrier. Conclusion: Parents of children with ASD were enthusiastic but also expressed concerns about WGS. These findings will be useful to future research with this and other populations.

ISBN: 9781303073489Subjects--Topical Terms:

1017730
Biology, Genetics.

Attitudes toward Whole Genome Sequencing among Parents of Children with Autism Spectrum Disorder: A Qualitative Interview Study.
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520 $a Background: Whole genome sequencing (WGS) is increasingly used for research and clinical purposes. This study explored attitudes of parents of children with a suspected autism spectrum disorder (ASD) toward WGS. Methods: A topic guide informed by the Theory of Planned Behavior was developed covering perceived benefits, concerns, barriers, and facilitators regarding WGS. Participants also summarized likely major factors in their decision. Interviews were audio-recorded, transcribed and analyzed for themes using framework analysis. Results: Participants (n=10) were generally in favor of WGS. The most recurring themes were: helping their affected child; concerns that secondary findings could be emotionally overwhelming; facilitators relating to access, e.g. living near a major medical center. When summarizing, money/insurance issues were most raised; this was also the most recurring barrier. Conclusion: Parents of children with ASD were enthusiastic but also expressed concerns about WGS. These findings will be useful to future research with this and other populations.
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