東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Translating molecular biomarkers int...

Weiner, Russell.

FindBook

Google Book

Amazon

博客來

Translating molecular biomarkers into clinical assays = techniques and applications /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Translating molecular biomarkers into clinical assays/ edited by Russell Weiner, Marian Kelley.
其他題名:	techniques and applications /
其他作者:	Weiner, Russell.
出版者:	Cham :Springer International Publishing : : 2016.,
面頁冊數:	xi, 212 p. :ill., digital ;24 cm.
內容註:	Foreword -- Fit-For-Purpose Validation -- Biomarkers in Drug Discovery and Development: Pre-Analytical and Analytical Considerations -- Biomarker Discovery -- Application of Quantitative Biomeasures in Early Drug Discovery -- Biomarkers in discovery and preclinical phase during drug development -- Incorporating clinical biomarkers into clinical trials -- Perspectives on Tissue Biobanking for Personalized Medicine -- The role of commercial biomarker assay kits in preclinical and clinical trials kits -- Quantification of protein biomarkers using liquid chromatography tandem mass spectrometry -- LC/MS methods for small Molecule biomarkers -- Cell-based Assays -- New Technologies for Cellular Analysis -- Flow cytometry methods for the Clinical Development of Immunomodulatory Biologics -- Key mass spectrometry techniques used in clinical biomarker research -- Clinical Genomic Biomarker Assay Development: Technologies and Issues -- Implementation of Immunohistochemistry assays for clinical trial sample analyses -- Strategic Approach to Outsourcing Clinical Biomarker Assays through CRO Relationships -- In situ hybridization (ISH) in Clinical Biomarker Development.
Contained By:	Springer eBooks
標題:	Biochemical markers. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-40793-7
ISBN:	9783319407937

Translating molecular biomarkers into clinical assays = techniques and applications /
Translating molecular biomarkers into clinical assaystechniques and applications /[electronic resource] :edited by Russell Weiner, Marian Kelley. - Cham :Springer International Publishing :2016. - xi, 212 p. :ill., digital ;24 cm. - AAPS advances in the pharmaceutical sciences series,2210-7371. - AAPS advances in the pharmaceutical sciences series..

Foreword -- Fit-For-Purpose Validation -- Biomarkers in Drug Discovery and Development: Pre-Analytical and Analytical Considerations -- Biomarker Discovery -- Application of Quantitative Biomeasures in Early Drug Discovery -- Biomarkers in discovery and preclinical phase during drug development -- Incorporating clinical biomarkers into clinical trials -- Perspectives on Tissue Biobanking for Personalized Medicine -- The role of commercial biomarker assay kits in preclinical and clinical trials kits -- Quantification of protein biomarkers using liquid chromatography tandem mass spectrometry -- LC/MS methods for small Molecule biomarkers -- Cell-based Assays -- New Technologies for Cellular Analysis -- Flow cytometry methods for the Clinical Development of Immunomodulatory Biologics -- Key mass spectrometry techniques used in clinical biomarker research -- Clinical Genomic Biomarker Assay Development: Technologies and Issues -- Implementation of Immunohistochemistry assays for clinical trial sample analyses -- Strategic Approach to Outsourcing Clinical Biomarker Assays through CRO Relationships -- In situ hybridization (ISH) in Clinical Biomarker Development.

This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.

ISBN: 9783319407937

Standard No.: 10.1007/978-3-319-40793-7doiSubjects--Topical Terms:

587592
Biochemical markers.

LC Class. No.: R853.B54

Dewey Class. No.: 610.72

Translating molecular biomarkers into clinical assays = techniques and applications /
LDR:03254nmm a2200325 a 4500 001 2047645
003 DE-He213
005 20160822160441.0
006 m d
007 cr nn 008maaau
008 170319s2016 gw s 0 eng d
020 $a 9783319407937 $q (electronic bk.)
020 $a 9783319407920 $q (paper)
024 7 $a 10.1007/978-3-319-40793-7 $2 doi
035 $a 978-3-319-40793-7
040 $a GP $c GP
041 0 $a eng
050 4 $a R853.B54
072 7 $a TDCW $2 bicssc
072 7 $a MED072000 $2 bisacsh
082 0 4 $a 610.72 $2 23
090 $a R853.B54 $b T772 2016
245 0 0 $a Translating molecular biomarkers into clinical assays $h [electronic resource] : $b techniques and applications / $c edited by Russell Weiner, Marian Kelley.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a xi, 212 p. : $b ill., digital ; $c 24 cm.
490 1 $a AAPS advances in the pharmaceutical sciences series, $x 2210-7371
505 0 $a Foreword -- Fit-For-Purpose Validation -- Biomarkers in Drug Discovery and Development: Pre-Analytical and Analytical Considerations -- Biomarker Discovery -- Application of Quantitative Biomeasures in Early Drug Discovery -- Biomarkers in discovery and preclinical phase during drug development -- Incorporating clinical biomarkers into clinical trials -- Perspectives on Tissue Biobanking for Personalized Medicine -- The role of commercial biomarker assay kits in preclinical and clinical trials kits -- Quantification of protein biomarkers using liquid chromatography tandem mass spectrometry -- LC/MS methods for small Molecule biomarkers -- Cell-based Assays -- New Technologies for Cellular Analysis -- Flow cytometry methods for the Clinical Development of Immunomodulatory Biologics -- Key mass spectrometry techniques used in clinical biomarker research -- Clinical Genomic Biomarker Assay Development: Technologies and Issues -- Implementation of Immunohistochemistry assays for clinical trial sample analyses -- Strategic Approach to Outsourcing Clinical Biomarker Assays through CRO Relationships -- In situ hybridization (ISH) in Clinical Biomarker Development.
520 $a This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.
650 0 $a Biochemical markers. $3 587592
650 1 4 $a Biomedicine. $3 890831
650 2 4 $a Pharmaceutical Sciences/Technology. $3 1001579
650 2 4 $a Pharmacy. $3 636101
700 1 $a Weiner, Russell. $3 2209757
700 1 $a Kelley, Marian. $3 2209758
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a AAPS advances in the pharmaceutical sciences series. $3 2058009
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-40793-7
950 $a Biomedical and Life Sciences (Springer-11642)