東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Cellular ageing and replicative sene...

Rattan, Suresh I.S.

FindBook

Google Book

Amazon

博客來

Cellular ageing and replicative senescence

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Cellular ageing and replicative senescence/ edited by Suresh I.S. Rattan, Leonard Hayflick.
其他作者:	Rattan, Suresh I.S.
出版者:	Cham :Springer International Publishing : : 2016.,
面頁冊數:	viii, 364 p. :ill. (some col.), digital ;24 cm.
內容註:	Preface -- Section I History and origins -- Origins of the Hayflick system, the phenomenon and the limit -- Early testing and development of the Hayflick system -- Section II Serial passaging and progressive changes -- Slowing down of the cell cycle -- Ageing of cells in the centenarians and long-lived -- Aging of the stem cells -- Aging and senescence in the immune cells in vitro and in vivo -- Accelerated cellular aging in progeroid syndromes -- Telomere and genomic instability -- Mechanistic explanation for cellular aging in vitro: the commitment theory -- Modelling cellular aging senescence -- Section-III Regulation, and senescence -- Cell cycle checkpoints and regulators of senescence -- Oxidative stress and cellular ageing -- Biomarkers of replicative senescence revisited -- Cellular aging and tumour regulation -- Declining Protein turnover and degradation -- Section IV Modulating the system -- Stress induced premature senescence (SIPS) -- Mild stress-induced hormesis -- Food, hormones and growth factors in cellular aging -- sncRNAs in cellular aging and senescence -- Elimination of senescent cells for rejuvenation -- Section-V RECAPITULATION -- The past, present and the future of cellular aging and replicative senescence -- Index.
Contained By:	Springer eBooks
標題:	Aging - Molecular aspects. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-26239-0
ISBN:	9783319262390

Cellular ageing and replicative senescence
Cellular ageing and replicative senescence[electronic resource] /edited by Suresh I.S. Rattan, Leonard Hayflick. - Cham :Springer International Publishing :2016. - viii, 364 p. :ill. (some col.), digital ;24 cm. - Healthy ageing and longevity,v.42199-9007 ;. - Healthy ageing and longevity ;v.1..

Preface -- Section I History and origins -- Origins of the Hayflick system, the phenomenon and the limit -- Early testing and development of the Hayflick system -- Section II Serial passaging and progressive changes -- Slowing down of the cell cycle -- Ageing of cells in the centenarians and long-lived -- Aging of the stem cells -- Aging and senescence in the immune cells in vitro and in vivo -- Accelerated cellular aging in progeroid syndromes -- Telomere and genomic instability -- Mechanistic explanation for cellular aging in vitro: the commitment theory -- Modelling cellular aging senescence -- Section-III Regulation, and senescence -- Cell cycle checkpoints and regulators of senescence -- Oxidative stress and cellular ageing -- Biomarkers of replicative senescence revisited -- Cellular aging and tumour regulation -- Declining Protein turnover and degradation -- Section IV Modulating the system -- Stress induced premature senescence (SIPS) -- Mild stress-induced hormesis -- Food, hormones and growth factors in cellular aging -- sncRNAs in cellular aging and senescence -- Elimination of senescent cells for rejuvenation -- Section-V RECAPITULATION -- The past, present and the future of cellular aging and replicative senescence -- Index.

This book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer. Cellular Ageing and Replicative Senescence revisits more than fifty-five years of research based on the discovery that cultured normal cells are mortal and the interpretation that this phenomenon is associated with the origins of ageing. The mortality of normal cells and the immortality of cancer cells were also reported to have in vivo counterparts. Thus began the field of cytogerontology. Cellular Ageing and Replicative Senescence is organized into five sections: history and origins; serial passaging and progressive ageing; cell cycle arrest and senescence; system modulation; and recapitulation and future expectations. These issues are discussed by leading thinkers and researchers in biogerontology and cytogerontology. This collection of articles provides state-of-the-art information, and will encourage students, teachers, health care professionals and others interested in the biology of ageing to explore the fascinating and challenging question of why and how our cells age, and what can and cannot be done about it.

ISBN: 9783319262390

Standard No.: 10.1007/978-3-319-26239-0doiSubjects--Topical Terms:

541762
Aging
--Molecular aspects.

LC Class. No.: QP86

Dewey Class. No.: 571.878

Cellular ageing and replicative senescence
LDR:03560nmm a2200337 a 4500 001 2037834
003 DE-He213
005 20161019100234.0
006 m d
007 cr nn 008maaau
008 161209s2016 gw s 0 eng d
020 $a 9783319262390 $q (electronic bk.)
020 $a 9783319262376 $q (paper)
024 7 $a 10.1007/978-3-319-26239-0 $2 doi
035 $a 978-3-319-26239-0
040 $a GP $c GP
041 0 $a eng
050 4 $a QP86
072 7 $a MFN $2 bicssc
072 7 $a MED107000 $2 bisacsh
072 7 $a SCI029000 $2 bisacsh
082 0 4 $a 571.878 $2 23
090 $a QP86 $b .C393 2016
245 0 0 $a Cellular ageing and replicative senescence $h [electronic resource] / $c edited by Suresh I.S. Rattan, Leonard Hayflick.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a viii, 364 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Healthy ageing and longevity, $x 2199-9007 ; $v v.4
505 0 $a Preface -- Section I History and origins -- Origins of the Hayflick system, the phenomenon and the limit -- Early testing and development of the Hayflick system -- Section II Serial passaging and progressive changes -- Slowing down of the cell cycle -- Ageing of cells in the centenarians and long-lived -- Aging of the stem cells -- Aging and senescence in the immune cells in vitro and in vivo -- Accelerated cellular aging in progeroid syndromes -- Telomere and genomic instability -- Mechanistic explanation for cellular aging in vitro: the commitment theory -- Modelling cellular aging senescence -- Section-III Regulation, and senescence -- Cell cycle checkpoints and regulators of senescence -- Oxidative stress and cellular ageing -- Biomarkers of replicative senescence revisited -- Cellular aging and tumour regulation -- Declining Protein turnover and degradation -- Section IV Modulating the system -- Stress induced premature senescence (SIPS) -- Mild stress-induced hormesis -- Food, hormones and growth factors in cellular aging -- sncRNAs in cellular aging and senescence -- Elimination of senescent cells for rejuvenation -- Section-V RECAPITULATION -- The past, present and the future of cellular aging and replicative senescence -- Index.
520 $a This book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer. Cellular Ageing and Replicative Senescence revisits more than fifty-five years of research based on the discovery that cultured normal cells are mortal and the interpretation that this phenomenon is associated with the origins of ageing. The mortality of normal cells and the immortality of cancer cells were also reported to have in vivo counterparts. Thus began the field of cytogerontology. Cellular Ageing and Replicative Senescence is organized into five sections: history and origins; serial passaging and progressive ageing; cell cycle arrest and senescence; system modulation; and recapitulation and future expectations. These issues are discussed by leading thinkers and researchers in biogerontology and cytogerontology. This collection of articles provides state-of-the-art information, and will encourage students, teachers, health care professionals and others interested in the biology of ageing to explore the fascinating and challenging question of why and how our cells age, and what can and cannot be done about it.
650 0 $a Aging $x Molecular aspects. $3 541762
650 1 4 $a Biomedicine. $3 890831
650 2 4 $a Cytogenetics. $3 664496
650 2 4 $a Cell Biology. $3 892383
650 2 4 $a Geriatrics/Gerontology. $3 894395
700 1 $a Rattan, Suresh I.S. $3 1622137
700 1 $a Hayflick, Leonard. $3 2194658
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Healthy ageing and longevity ; $v v.1. $3 2088709
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-26239-0
950 $a Biomedical and Life Sciences (Springer-11642)