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The male role in pregnancy loss and ...

Bronson, Richard.

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The male role in pregnancy loss and embryo implantation failure

Record Type:	Electronic resources : Monograph/item
Title/Author:	The male role in pregnancy loss and embryo implantation failure/ edited by Richard Bronson.
other author:	Bronson, Richard.
Published:	Cham :Springer International Publishing : : 2015.,
Description:	x, 228 p. :ill., digital ;24 cm.
[NT 15003449]:	Preface -- Meiotic Non-disjunction - Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa -- Damage to Sperm DNA Mediated by Reactive Oxygen Species: Its Impact on Human Reproduction and the Health Trajectory of Offspring -- Small RNAs: Their Possible Roles in Reproductive Failure -- The Sperm Epigenome, Male Aging and Potential Effects on the Embryo -- The Role of Uterine NK Cells in Normal Reproduction and Reproductive Disorders -- Seminal fluid Signaling in the Female Reproductive Tract: Implications for Reproductive Success and Offspring Health -- Role of Seminal Plasma in Human Female Reproductive Failure: Immunomodulation, Inflammation and Infections -- Human Leukocyte Antigen-G Within the Male Reproductive System - Implications for Reproduction -- Prostasomes - Their Characterization: Implications for Human Reproduction -- The Paternal Contribution to Fetal Tolerance -- Index.
Contained By:	Springer eBooks
Subject:	Spermatozoa - Motility -
Online resource:	http://dx.doi.org/10.1007/978-3-319-18881-2
ISBN:	9783319188812 (electronic bk.)

The male role in pregnancy loss and embryo implantation failure
The male role in pregnancy loss and embryo implantation failure[electronic resource] /edited by Richard Bronson. - Cham :Springer International Publishing :2015. - x, 228 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.8680065-2598 ;. - Advances in experimental medicine and biology ;946..

Preface -- Meiotic Non-disjunction - Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa -- Damage to Sperm DNA Mediated by Reactive Oxygen Species: Its Impact on Human Reproduction and the Health Trajectory of Offspring -- Small RNAs: Their Possible Roles in Reproductive Failure -- The Sperm Epigenome, Male Aging and Potential Effects on the Embryo -- The Role of Uterine NK Cells in Normal Reproduction and Reproductive Disorders -- Seminal fluid Signaling in the Female Reproductive Tract: Implications for Reproductive Success and Offspring Health -- Role of Seminal Plasma in Human Female Reproductive Failure: Immunomodulation, Inflammation and Infections -- Human Leukocyte Antigen-G Within the Male Reproductive System - Implications for Reproduction -- Prostasomes - Their Characterization: Implications for Human Reproduction -- The Paternal Contribution to Fetal Tolerance -- Index.

Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors.

ISBN: 9783319188812 (electronic bk.)

Standard No.: 10.1007/978-3-319-18881-2doiSubjects--Topical Terms:

2157541
Spermatozoa
--Motility

LC Class. No.: RC889.2

Dewey Class. No.: 612.61

The male role in pregnancy loss and embryo implantation failure
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245 0 4 $a The male role in pregnancy loss and embryo implantation failure $h [electronic resource] / $c edited by Richard Bronson.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2015.
300 $a x, 228 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.868
505 0 $a Preface -- Meiotic Non-disjunction - Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa -- Damage to Sperm DNA Mediated by Reactive Oxygen Species: Its Impact on Human Reproduction and the Health Trajectory of Offspring -- Small RNAs: Their Possible Roles in Reproductive Failure -- The Sperm Epigenome, Male Aging and Potential Effects on the Embryo -- The Role of Uterine NK Cells in Normal Reproduction and Reproductive Disorders -- Seminal fluid Signaling in the Female Reproductive Tract: Implications for Reproductive Success and Offspring Health -- Role of Seminal Plasma in Human Female Reproductive Failure: Immunomodulation, Inflammation and Infections -- Human Leukocyte Antigen-G Within the Male Reproductive System - Implications for Reproduction -- Prostasomes - Their Characterization: Implications for Human Reproduction -- The Paternal Contribution to Fetal Tolerance -- Index.
520 $a Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors.
650 0 $a Spermatozoa $x Motility $x Disorders. $3 2157541
650 0 $a Human embryo $x Transplantation. $3 2077425
650 0 $a Human reproduction $x Immunological aspects. $3 719648
650 1 4 $a Life Sciences. $3 890838
650 2 4 $a Embryology. $3 636588
650 2 4 $a Reproductive Medicine. $3 874352
650 2 4 $a Cytogenetics. $3 664496
700 1 $a Bronson, Richard. $3 681228
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830 0 $a Advances in experimental medicine and biology ; $v 946. $3 1565434
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-18881-2
950 $a Biomedical and Life Sciences (Springer-11642)