內容註: |
Machine generated contents note: Part A: Molecular Signaling Mechanisms: from Pathways to Networks -- Chapter 1: Sending of the Wnt signal and its reception at the membrane (an overview) / Xi He, Rik Korswagen -- Chapter 2: Introduction to Wnt Signal transduction in the cytoplasm / Xi He -- Chapter 3: Regulation of gene expression by Wnt signaling in the nucleus (an overview) / Marian Waterman, Ken Cadigan -- Chapter 4: Wnt target genes: Insights from bioinformatics / Ken Cadigan -- Chapter 5: Introduction to [beta]-catenin-independent Wnt signaling pathways / Michael Kuhl, David Strutt -- Chapter 6: Choice and specificity of Wnt signaling pathways / Guido Zaman, Stuart Aaronson -- Chapter 7: The Cell Biology of Wnt signaling / John Wallingford, Kikuchi -- Chapter 8: New insights from proteomic analysis of Wnt signaling / Ben Major -- Chapter 9: New insights about Wnt pathway mechanisms from global siRNA screens / Ram Dasgupta -- Chapter 10: Insights from mathematical modeling on Wnt signaling network / M. Kuhl -- Chapter 11: The evolution of Wnt signaling / Jenifer Croce (David McClay), Thomas Holstein, Linda Holland -- Part B: Selected key molecules in Wnt signaling -- Chapter 12: The Wnt signal / Roel Nusse, Karl Willert -- Chapter 13: Secreted Wnt inhibitors or modulators / Herbert Steinbeisser, Robert Kypta, Masanori Taira, Paola Bovolenta and Javier Lopez-Rios -- Chapter 14: Frizzleds as G-Protein Coupled Receptors / Gunnar Schulte (Craig Malbon and Randall Moon) -- Chapter 15: Dishevelled, at the crossroads of pathways / Mariann Bienz, John Wallinford, Vitezslav Bryja -- Chapter 16: [beta]-catenin, jobs for one protein in signaling and cell adhesion / Jonathan Pettitt, Cara Gottardi, Koni Basler, Bienz -- Chapter 17: Variety of TCF/LEF structure and function in vertebrate Wnt signaling / Mariann Waterman, Hoppler, Bradley Merrill -- Chapter 18: Insights from Structural Analysis of protein-protein interactions by Wnt Pathway Components and functional multi-protein complex formation / Wenqing Xu -- Part C: Wnt Signaling in Embryonic Development and Adult Tissue Homeostasis -- Chapter 19: Wnt signaling in Early embryonic development: From Fertilization To Gastrulation (an introduction) / Stefan Hoppler -- Chapter 20: Wnt signaling in Embryonic Stem Cells: Insights into Early Mammalian Development / Kathy Davidson -- Chapter 21: Wnt signaling specifying Neural Lineages / Corinne Houart, Richard Dorsky -- Chapter 22: Wnt signaling in Heart Organogenesis / Morressey, Hoppler, M. Kuhl -- Chapter 23: Wnt signaling in Kidney organogenesis / Andy McMahon, Seppo Vainio -- Chapter 24: Wnt signaling regulation of tissue architecture (EMT and MET) and morphogenesis / Liz Vincan -- Chapter 25: Wnt Signaling in Tissue Homeostasis in Adults / Elaine Fuchs, Hans Clevers -- Chapter 26: Restoring Tissue Homeostasis: Wnt Signaling in Tissue Regeneration After Acute Injury / Author tbd -- PART D: Wnt Signaling In Chronic Disease -- Chapter 27: Wnt signaling in Disease (an overview) / Randall Moon -- Chapter 28: Wnt signaling in Colorectal Cancer / Paul Polakis or Riccardo Fodde, Owen Sansom -- Chapter 29: Wnt signaling in Melanoma / Andy Chien -- Chapter 30: Wnt signaling in psychiatric disease and dementia / Stephen Haggarty -- Chapter 31: Wnt signaling Therapeutics / Trevor Dale, Randall Moon, et al. |