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Affinity and efficacy = the componen...

Ehlert, Frederick J.

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Affinity and efficacy = the components of drug-receptor interactions /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Affinity and efficacy/ Frederick J. Ehlert.
其他題名:	the components of drug-receptor interactions /
其他題名:	Components of drug-receptor interactions
作者:	Ehlert, Frederick J.
出版者:	New Jersey :World Scientific, : 2014.,
面頁冊數:	1 online resource.
內容註:	Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.
標題:	Drug receptors. -
電子資源:	http://www.worldscientific.com/worldscibooks/10.1142/7888#t=toc
ISBN:	9789814324229

Affinity and efficacy = the components of drug-receptor interactions /
Ehlert, Frederick J.

Affinity and efficacythe components of drug-receptor interactions /[electronic resource] :Components of drug-receptor interactionsFrederick J. Ehlert. - New Jersey :World Scientific,2014. - 1 online resource.

Includes bibliographical references.

Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.

ISBN: 9789814324229Subjects--Topical Terms:

690365
Drug receptors.

LC Class. No.: RM302.4

Dewey Class. No.: 615.7/0452

National Library of Medicine Call No.: QV 36

Affinity and efficacy = the components of drug-receptor interactions /
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