東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Resistance to targeted ABC transport...

Efferth, Thomas.

Linked to FindBook

Google Book

Amazon

博客來

Resistance to targeted ABC transporters in cancer

Record Type:	Electronic resources : Monograph/item
Title/Author:	Resistance to targeted ABC transporters in cancer/ edited by Thomas Efferth.
other author:	Efferth, Thomas.
Published:	Cham :Springer International Publishing : : 2015.,
Description:	x, 300 p. :ill. (some col.), digital ;24 cm.
[NT 15003449]:	Role of P-glycoprotein for resistance of tumors to anticancer drugs: From bench to bedside -- Clinical relevance of multidrug-resistance-related proteins (MRPs) for anticancer drug resistance and prognosis -- Role of Breast Cancer Resistance Protein (BCRP, ABCG2) in Cancer Outcomes and Drug Resistance -- A new strategy of ALA-photodynamic cancer therapy: Inhibition of ABC transporter ABCG2 -- ABC transporters in cancer stem-like cells -- Radiopharmaceuticals for the imaging of ABC-transporter-mediated multidrug resistance in cancer -- Modulation of P-glycoprotein-mediated multidrug resistance by synthetic and phytochemical small molecules, monoclonal antibodies and therapeutic nucleic acids -- ABC transporter modulatory drugs from marine sources: A new approach to overcome drug resistance in cancer -- The role of ABC multidrug transporters in resistance to targeted anti-cancer kinase inhibitors -- Nanotechnology to combat multidrug resistance in cancer -- Drugs affecting epigenetic modifications of ABC transporters.
Contained By:	Springer eBooks
Subject:	Drug resistance in cancer cells. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-09801-2
ISBN:	9783319098012 (electronic bk.)

Resistance to targeted ABC transporters in cancer
Resistance to targeted ABC transporters in cancer[electronic resource] /edited by Thomas Efferth. - Cham :Springer International Publishing :2015. - x, 300 p. :ill. (some col.), digital ;24 cm. - Resistance to targeted anti-cancer therapeutics,v.42196-5501 ;. - Resistance to targeted anti-cancer therapeutics ;v.4..

Role of P-glycoprotein for resistance of tumors to anticancer drugs: From bench to bedside -- Clinical relevance of multidrug-resistance-related proteins (MRPs) for anticancer drug resistance and prognosis -- Role of Breast Cancer Resistance Protein (BCRP, ABCG2) in Cancer Outcomes and Drug Resistance -- A new strategy of ALA-photodynamic cancer therapy: Inhibition of ABC transporter ABCG2 -- ABC transporters in cancer stem-like cells -- Radiopharmaceuticals for the imaging of ABC-transporter-mediated multidrug resistance in cancer -- Modulation of P-glycoprotein-mediated multidrug resistance by synthetic and phytochemical small molecules, monoclonal antibodies and therapeutic nucleic acids -- ABC transporter modulatory drugs from marine sources: A new approach to overcome drug resistance in cancer -- The role of ABC multidrug transporters in resistance to targeted anti-cancer kinase inhibitors -- Nanotechnology to combat multidrug resistance in cancer -- Drugs affecting epigenetic modifications of ABC transporters.

This volume covers the most current topics relevant to ABC transporters and resistance to novel and established anticancer drugs, prognosis of patients to compounds to modulate multidrug resistance, compounds used in photodynamic therapy, tyrosine kinase inhibitors and others. Furthermore, the potential of radiopharmaceuticals for diagnosis of multidrug-resistant tumors is also discussed. The development of resistance is a major obstacle in cancer chemotherapy since decades. Drug resistance may develop during repeated treatment cycles after initially successful therapy (acquired or secondary resistance). Alternatively, tumors may be resistant from the beginning (inherent or primary resistance). The failure of chemotherapy is a major reason for the fatal outcome of tumor diseases in many patients. Even worse, tumors frequently develop not only resistance to single drugs, but also to many others at the same time. This phenomenon was termed multidrug resistance and decreases the success rates of therapy regimens with combinations of structurally and functionally different drugs. The uncommonly broad spectrum of anticancer agents that are transported by ABC transporters makes these proteins exquisite targets to search for compounds that inhibit their transport function. A huge amount of compounds from many pharmacologically established drug were observed to inhibit ABC transporters and to reverse multidrug resistance all of these topics and more is explored in this volume.

ISBN: 9783319098012 (electronic bk.)

Standard No.: 10.1007/978-3-319-09801-2doiSubjects--Topical Terms:

658434
Drug resistance in cancer cells.

LC Class. No.: RC271.C5

Dewey Class. No.: 616.994061

Resistance to targeted ABC transporters in cancer
LDR:03560nmm a2200325 a 4500 001 1992972
003 DE-He213
005 20150609145556.0
006 m d
007 cr nn 008maaau
008 151019s2015 gw s 0 eng d
020 $a 9783319098012 (electronic bk.)
020 $a 9783319098005 (paper)
024 7 $a 10.1007/978-3-319-09801-2 $2 doi
035 $a 978-3-319-09801-2
040 $a GP $c GP
041 0 $a eng
050 4 $a RC271.C5
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
082 0 4 $a 616.994061 $2 23
090 $a RC271.C5 $b R433 2015
245 0 0 $a Resistance to targeted ABC transporters in cancer $h [electronic resource] / $c edited by Thomas Efferth.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2015.
300 $a x, 300 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Resistance to targeted anti-cancer therapeutics, $x 2196-5501 ; $v v.4
505 0 $a Role of P-glycoprotein for resistance of tumors to anticancer drugs: From bench to bedside -- Clinical relevance of multidrug-resistance-related proteins (MRPs) for anticancer drug resistance and prognosis -- Role of Breast Cancer Resistance Protein (BCRP, ABCG2) in Cancer Outcomes and Drug Resistance -- A new strategy of ALA-photodynamic cancer therapy: Inhibition of ABC transporter ABCG2 -- ABC transporters in cancer stem-like cells -- Radiopharmaceuticals for the imaging of ABC-transporter-mediated multidrug resistance in cancer -- Modulation of P-glycoprotein-mediated multidrug resistance by synthetic and phytochemical small molecules, monoclonal antibodies and therapeutic nucleic acids -- ABC transporter modulatory drugs from marine sources: A new approach to overcome drug resistance in cancer -- The role of ABC multidrug transporters in resistance to targeted anti-cancer kinase inhibitors -- Nanotechnology to combat multidrug resistance in cancer -- Drugs affecting epigenetic modifications of ABC transporters.
520 $a This volume covers the most current topics relevant to ABC transporters and resistance to novel and established anticancer drugs, prognosis of patients to compounds to modulate multidrug resistance, compounds used in photodynamic therapy, tyrosine kinase inhibitors and others. Furthermore, the potential of radiopharmaceuticals for diagnosis of multidrug-resistant tumors is also discussed. The development of resistance is a major obstacle in cancer chemotherapy since decades. Drug resistance may develop during repeated treatment cycles after initially successful therapy (acquired or secondary resistance). Alternatively, tumors may be resistant from the beginning (inherent or primary resistance). The failure of chemotherapy is a major reason for the fatal outcome of tumor diseases in many patients. Even worse, tumors frequently develop not only resistance to single drugs, but also to many others at the same time. This phenomenon was termed multidrug resistance and decreases the success rates of therapy regimens with combinations of structurally and functionally different drugs. The uncommonly broad spectrum of anticancer agents that are transported by ABC transporters makes these proteins exquisite targets to search for compounds that inhibit their transport function. A huge amount of compounds from many pharmacologically established drug were observed to inhibit ABC transporters and to reverse multidrug resistance all of these topics and more is explored in this volume.
650 0 $a Drug resistance in cancer cells. $3 658434
650 0 $a Cancer $x Chemotherapy. $3 753516
650 1 4 $a Biomedicine. $3 890831
650 2 4 $a Cancer Research. $3 891172
650 2 4 $a Drug Resistance. $3 836316
650 2 4 $a Molecular Medicine. $3 890952
700 1 $a Efferth, Thomas. $3 2130879
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Resistance to targeted anti-cancer therapeutics ; $v v.4. $3 2130880
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-09801-2
950 $a Biomedical and Life Sciences (Springer-11642)