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Handbook of drug screening

Seethala, Ramakrishna, (1947-)

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Handbook of drug screening

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Handbook of drug screening/ edited by Ramakrishna Seethala, Litao Zhang.
其他作者:	Seethala, Ramakrishna,
出版者:	New York :Informa Healthcare, : c2009.,
面頁冊數:	xiii, 489 p. :ill.
內容註:	1. Key factors for successful high-throughput screening / John G. Houston -- 2. Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- 3. Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- 4. Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- 5. Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- 6. Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic --
內容註:	7. Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao Zhang -- 8. Emerging novel high-throughput screening technologies for cell-based assays / ILona Kariv ... [et al.] -- 9. In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop -- 10. Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel -- 11. Protein kinases and phosphatases / Pirthipal Singh -- 12. MicroRNA strategies in drug discovery / Wishva B. Herath ... [et al.] -- 13. Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli --
內容註:	14. Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillan -- 15. High-content screening with a special emphasis on cytotoxicity and cell health measurements / Ralph J. Garippa and Ann F. Hoffman -- 16. Effective application of drug metabolism and pharmacokinetics in drug discovery / Sharon Diamond and Swanny Yeleswaram -- 17. Compound management for drug discovery : an overview / Moneesh Chatterjee and Martyn N. Banks -- 18. Practical approach to quantitative high throughput screening / Wei Zheng, Ke Liu, and James Inglese -- 19. Enabling the large-scale analysis of quantitative high-throughput screening data / Noel T. Southall ... [et al.] -- 20. Application of nanobiotechnologies for drug discovery / K.K. Jain.
標題:	Drug development - Handbooks, manuals, etc. -
電子資源:	http://marc.crcnetbase.com/isbn/9781420061697Distributed by publisher. Purchase or institutional license may be required for access.
ISBN:	9781420061697 (ebook : PDF)

Handbook of drug screening
Handbook of drug screening[electronic resource] /edited by Ramakrishna Seethala, Litao Zhang. - 2nd ed. - New York :Informa Healthcare,c2009. - xiii, 489 p. :ill. - Drugs and the pharmaceutical sciences ;196. - Drugs and the pharmaceutical sciences ;v. 183-184.

Includes bibliographical references and index.

1. Key factors for successful high-throughput screening / John G. Houston -- 2. Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- 3. Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- 4. Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- 5. Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- 6. Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic --

Mode of access: World Wide Web.

ISBN: 9781420061697 (ebook : PDF)Subjects--Topical Terms:

1359755
Drug development
--Handbooks, manuals, etc.Index Terms--Genre/Form:

542853
Electronic books.

Handbook of drug screening
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245 0 0 $a Handbook of drug screening $h [electronic resource] / $c edited by Ramakrishna Seethala, Litao Zhang.
250 $a 2nd ed.
260 $a New York : $b Informa Healthcare, $c c2009.
300 $a xiii, 489 p. : $b ill.
490 1 $a Drugs and the pharmaceutical sciences ; $v 196
504 $a Includes bibliographical references and index.
505 0 $a 1. Key factors for successful high-throughput screening / John G. Houston -- 2. Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- 3. Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- 4. Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- 5. Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- 6. Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic --
505 0 $a 7. Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao Zhang -- 8. Emerging novel high-throughput screening technologies for cell-based assays / ILona Kariv ... [et al.] -- 9. In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop -- 10. Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel -- 11. Protein kinases and phosphatases / Pirthipal Singh -- 12. MicroRNA strategies in drug discovery / Wishva B. Herath ... [et al.] -- 13. Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli --
505 0 $a 14. Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillan -- 15. High-content screening with a special emphasis on cytotoxicity and cell health measurements / Ralph J. Garippa and Ann F. Hoffman -- 16. Effective application of drug metabolism and pharmacokinetics in drug discovery / Sharon Diamond and Swanny Yeleswaram -- 17. Compound management for drug discovery : an overview / Moneesh Chatterjee and Martyn N. Banks -- 18. Practical approach to quantitative high throughput screening / Wei Zheng, Ke Liu, and James Inglese -- 19. Enabling the large-scale analysis of quantitative high-throughput screening data / Noel T. Southall ... [et al.] -- 20. Application of nanobiotechnologies for drug discovery / K.K. Jain.
530 $a Also available in print edition.
538 $a Mode of access: World Wide Web.
650 0 $a Drug development $v Handbooks, manuals, etc. $3 1359755
650 0 $a Drugs $x Testing $v Handbooks, manuals, etc. $3 1359756
655 7 $a Electronic books. $2 lcsh $3 542853
700 1 $a Seethala, Ramakrishna, $d 1947- $3 726825
700 1 $a Zhang, Litao. $3 1359754
776 1 $z 9781420061680 (hardcover : alk. paper) $z 1420061682
830 0 $a Drugs and the pharmaceutical sciences ; $v v. 183-184 $3 1359366
856 4 0 $u http://marc.crcnetbase.com/isbn/9781420061697 $q application/PDF $z Distributed by publisher. Purchase or institutional license may be required for access.